What is he best known for?
The fields of study he is best known for:
Scot A. Wolfe spends much of his time researching Genetics, Computational biology, Cell biology, Gene and Zebrafish.
His works in Regulation of gene expression, Binding site, Genome, Drosophila melanogaster and Induced pluripotent stem cell are all subjects of inquiry into Genetics.
His research in Computational biology intersects with topics in Subgenomic mRNA, Zinc finger, Cas9 and DNA sequencing.
His biological study deals with issues like Embryonic stem cell, which deal with fields such as Zinc finger nuclease, Cell fate determination, Gene regulatory network and Model organism.
His research investigates the connection with Gene and areas like Function which intersect with concerns in Animal development, Vertebrate, Zoology and Gene expression.
The various areas that Scot A. Wolfe examines in his Zebrafish study include Chemokine, Chemokine receptor and Signal transduction, Notch signaling pathway.
His most cited work include:
- DNA recognition by Cys2His2 zinc finger proteins. (756 citations)
- Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases (684 citations)
- A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity (658 citations)
What are the main themes of his work throughout his whole career to date?
Scot A. Wolfe focuses on Computational biology, Genetics, Cell biology, Genome editing and Genome.
His Computational biology research integrates issues from Proteome, Guide RNA and DNA, DNA sequencing.
His study in Genetics concentrates on Zinc finger, Gene, Binding site, Zebrafish and Gene targeting.
His Cell biology study integrates concerns from other disciplines, such as Chromatin, Gene silencing, Enhancer and CHD4.
The Genome editing study which covers Cas9 that intersects with Nuclease, RNA and Subgenomic mRNA.
His Genome study combines topics from a wide range of disciplines, such as Drosophila Protein and Somatic cell.
He most often published in these fields:
- Computational biology (30.66%)
- Genetics (29.93%)
- Cell biology (20.44%)
What were the highlights of his more recent work (between 2016-2021)?
- Cell biology (20.44%)
- Genome editing (19.71%)
- Computational biology (30.66%)
In recent papers he was focusing on the following fields of study:
Scot A. Wolfe mainly focuses on Cell biology, Genome editing, Computational biology, Cas9 and Genome.
Scot A. Wolfe has researched Cell biology in several fields, including Chromatin, Transcription factor, CHD4 and Globin.
His Computational biology study combines topics in areas such as Proteome, Peak calling, DNA and Guide RNA.
His Cas9 research includes elements of RNA, Subgenomic mRNA, Nuclear localization sequence and Nuclease.
His Nuclease research entails a greater understanding of Genetics.
His biological study spans a wide range of topics, including Polymerase, Transcription and Somatic cell.
Between 2016 and 2021, his most popular works were:
- Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing (177 citations)
- Highly efficient therapeutic gene editing of human hematopoietic stem cells. (142 citations)
- Partial DNA-guided Cas9 enables genome editing with reduced off-target activity. (106 citations)
In his most recent research, the most cited papers focused on:
Scot A. Wolfe mostly deals with Cell biology, Genome editing, Computational biology, Cas9 and Nuclease.
His studies deal with areas such as Enhancer and Regulation of gene expression as well as Cell biology.
His studies in Computational biology integrate themes in fields like Biotinylation, Genome, Bioconductor and CRISPR.
In the subject of general Genome, his work in Genomics is often linked to Identification, thereby combining diverse domains of study.
His study on CRISPR is covered under Genetics.
Synthetic biology and In vivo is closely connected to RNA in his research, which is encompassed under the umbrella topic of Cas9.
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