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Biology and Biochemistry

D-Index
77
Citations
19660
World Ranking
4820
National Ranking
2325

Overview

Michael S. German is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, with substantial work also in Medicine. Subfields that characterize their work include Genetics, Surgery, Endocrinology, Diabetes and Metabolism, Immunology, and Molecular Biology.

The scientist's publications cover several main topics in biomedical research. These include Diabetes and associated disorders, Pancreatic function and diabetes, Adrenal Hormones and Disorders, T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, Diet, Metabolism, and Disease, and Cancer Genomics and Diagnostics.

Frequent publication venues for Michael S. German are Diabetes, eLife, Science Translational Medicine, Journal of Diabetes Science and Technology, and Diabetes Care.

Recent papers by Michael S. German illustrate a strong focus on autoimmune and diabetes-related research:

  • Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by proteome-wide PhIP-Seq (2020, eLife)
  • Lactation improves pancreatic β cell mass and function through serotonin production (2020, Science Translational Medicine)
  • The Need for Precision Medicine to be Applied to Diabetes (2020, Journal of Diabetes Science and Technology)
  • Diabetes With Multiple Autoimmune and Inflammatory Conditions Linked to an Activating SKAP2 Mutation (2021, Diabetes Care)
  • A genomic data archive from the Network for Pancreatic Organ donors with Diabetes (2023, Scientific Data)

The scientist frequently collaborates with other researchers, with noted co-authors including Mark S. Anderson, Chester E. Chamberlain, David Scheel, Louis H. Philipson, and Sara E. Vazquez. These collaborations involve multiple joint publications.

Best Publications

  • Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.

    Valérie M. Schwitzgebel;David W. Scheel;Jennifer R. Conners;Julie Kalamaras

  • Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells

    L. Sussel;J. Kalamaras;D. J. Hartigan-O'connor;J. J. Meneses

  • Serotonin regulates pancreatic beta cell mass during pregnancy.

    Hail Kim;Yukiko Toyofuku;Francis C. Lynn;Francis C. Lynn;Eric W Chak

  • Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development.

    M Sander;A Neubüser;J Kalamaras;H C Ee

  • Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

    M. Sander;L. Sussel;J. Conners;D. Scheel

  • The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription.

    Giulia Catignani Kennedy;Michael S. German;William J. Rutter

  • Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex.

    Michael S. German;Juehu Wang;Robert B. Chadwick;William J. Rutter

  • Gene expression cascades in pancreatic development.

    Maria E. Wilson;David Scheel;Michael S. German

  • Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

    Rajarshi Ghosh;Likun Wang;Eric S. Wang;B. Gayani K. Perera

  • The beta cell transcription factors and development of the pancreas.

    M. Sander;Michael S. German

  • MicroRNA Expression Is Required for Pancreatic Islet Cell Genesis in the Mouse

    Francis C. Lynn;Peter Skewes-Cox;Yasuhiro Kosaka;Michael T. McManus

  • Rfx6 directs islet formation and insulin production in mice and humans

    Stuart B. Smith;Hui Qi Qu;Nadine Taleb;Nina Y. Kishimoto

  • Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates

    Maike Sander;Sussan Paydar;Johan Ericson;James Briscoe

  • Regulation of the Pancreatic Pro-Endocrine Gene Neurogenin3

    Jane C. Lee;Stewart B. Smith;Hirotaka Watada;Joseph Lin

  • Glucose sensing in pancreatic islet beta cells: the key role of glucokinase and the glycolytic intermediates.

    Michael S. German

  • Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

    Jacob Hald;J.Peter Hjorth;Michael S German;Ole D Madsen

  • Sox9 coordinates a transcriptional network in pancreatic progenitor cells

    F. C. Lynn;S. B. Smith;M. E. Wilson;K. Y. Yang

  • The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.

    Kinuko Ohneda;Raghavendra G. Mirmira;Juehu Wang;Jeffrey D. Johnson

  • The Insulin Gene Promoter: A Simplified Nomenclature

    German M;Ashcroft S;Docherty K;Edlund H

  • Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development.

    Stuart B. Smith;Hooi C. Ee;Jennifer R. Conners;Michael S. German

Frequent Co-Authors

Hirotaka Watada
Hirotaka Watada Juntendo University
Ira D. Goldfine
Ira D. Goldfine University of California, San Francisco
Stuart Smith
Stuart Smith UCSF Benioff Children's Hospital
Lori Sussel
Lori Sussel University of Colorado Denver
Maike Sander
Maike Sander Max Delbrück Center for Molecular Medicine
Harry Heimberg
Harry Heimberg Vrije Universiteit Brussel
William J. Rutter
William J. Rutter University of California, San Francisco
Ying Liu
Ying Liu The University of Texas Health Science Center at Houston
Michael T. McManus
Michael T. McManus University of California, San Francisco
Luc Bouwens
Luc Bouwens Vrije Universiteit Brussel

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