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Medicine

D-Index
91
Citations
34874
World Ranking
11648
National Ranking
5973

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Ira D. Goldfine is affiliated with the University of California, San Francisco in the United States and conducts research primarily in the field of medicine. Their work spans multiple subfields including cardiology and cardiovascular medicine, molecular biology, endocrinology, diabetes and metabolism, epidemiology, and physiology.

Their research addresses several interconnected topics related to metabolic and cardiovascular health. Key areas of focus include sphingolipid metabolism and signaling, lipid metabolism and disorders, diabetes, cardiovascular risks and lipoproteins, adipokines, inflammation and metabolic diseases, adipose tissue and metabolism, and cardiovascular disease and adiposity.

Goldfine's recent scholarly contributions include two notable papers. The first, published in 2021 in Current Opinion in Pharmacology, is titled "Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus." The second, from 2020 in EBioMedicine, is "Obesity-related hypoxia via miR-128 decreases insulin-receptor expression in human and mouse adipose tissue promoting systemic insulin resistance."

The frequent coauthors who have collaborated with Goldfine include:

  • John P. Kane
  • Clive R. Pullinger
  • Mary J. Malloy
  • Biagio Arcidiacono
  • Eusebio Chiefari

Goldfine's work has been published repeatedly in venues such as:

  • Current Opinion in Pharmacology
  • EBioMedicine

Among professional recognitions, Goldfine is a member of the Association of American Physicians.

Best Publications

  • Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes

    Joseph L. Evans;Ira D. Goldfine;Betty A. Maddux;Gerold M. Grodsky

  • Are Oxidative Stress−Activated Signaling Pathways Mediators of Insulin Resistance and β-Cell Dysfunction?

    Joseph L. Evans;Ira D. Goldfine;Betty A. Maddux;Gerold M. Grodsky

  • The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

    Yousuke Ebina;Leland Ellis;Kurt Jarnagin;Marc Edery

  • Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

    F. Frasca;G. Pandini;P. Scalia;L. Sciacca

  • Cholecystokinin bioactivity in human plasma. Molecular forms, responses to feeding, and relationship to gallbladder contraction.

    R A Liddle;I D Goldfine;M S Rosen;R A Taplitz

  • The molecular basis for oxidative stress-induced insulin resistance.

    Joseph L. Evans;Betty A. Maddux;Ira D. Goldfine

  • Bioassay of plasma cholecystokinin in rats: Effects of food, trypsin inhibitor, and alcohol

    Rodger A. Liddle;I.D. Goldfine;J.A. Williams

  • Protection Against Oxidative Stress—Induced Insulin Resistance in Rat L6 Muscle Cells by Micromolar Concentrations of α-Lipoic Acid

    Betty A. Maddux;Wendy See;John C. Lawrence;Amy L. Goldfine

  • Cholecystokinin receptors in the brain: characterization and distribution.

    Atsushi Saito;Hariharan Sankaran;Ira D. Goldfine;John A. Williams

  • Elevated insulin receptor content in human breast cancer

    V Papa;V Pezzino;A Costantino;A Belfiore

  • Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes

    David Meyre;David Meyre;Nabila Bouatia-Naji;Agnès Tounian;Chantal Samson

  • Mechanism of glucocorticoid receptor down-regulation by glucocorticoids.

    S Rosewicz;A R McDonald;B A Maddux;I D Goldfine

  • Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling.

    Giuseppe Pandini;Riccardo Vigneri;Angela Costantino;Francesco Frasca

  • The Insulin Receptor: Molecular Biology and Transmembrane Signaling

    Ira D. Goldfine

  • Binding of cholecystokinin to high affinity receptors on isolated rat pancreatic acini.

    H Sankaran;I D Goldfine;C W Deveney;K Y Wong

  • Insulin-like Growth Factor-I Receptors Are Overexpressed and Predict a Low Risk in Human Breast Cancer

    Vincenzo Papa;Biancamaria Gliozzo;Gary M. Clark;William L. McGuire

  • Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism.

    Laura Sciacca;Angela Costantino;Giuseppe Pandini;Rossana Mineo

  • Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes.

    Joseph L. Evans;Ira D. Goldfine

  • The Insulin-Pancreatic Acinar Axis

    John A Williams;Ira D Goldfine

  • PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification.

    Frank Rutsch;Sucheta Vaingankar;Kristen Johnson;Ira Goldfine

Frequent Co-Authors

John A. Williams
John A. Williams University of Michigan–Ann Arbor
Riccardo Vigneri
Riccardo Vigneri University of Catania
Clive R. Pullinger
Clive R. Pullinger University of California, San Francisco
Craig D. Logsdon
Craig D. Logsdon The University of Texas MD Anderson Cancer Center
Richard A. Roth
Richard A. Roth Stanford University
Gerald M. Reaven
Gerald M. Reaven Stanford University
John P. Kane
John P. Kane University of California, San Francisco
John Forsayeth
John Forsayeth University of California, San Francisco
Joseph A. Houmard
Joseph A. Houmard East Carolina University
Eric J. Brown
Eric J. Brown University of Pennsylvania

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