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Medicine

D-Index
87
Citations
26327
World Ranking
13704
National Ranking
522

Overview

Giorgio Sesti is affiliated with Sapienza University of Rome in Italy and has contributed extensively to the field of medicine, with a particular focus on cardiology, endocrinology, and metabolism. Their research portfolio includes 438 publications primarily within these disciplines, emphasizing both clinical and molecular approaches.

The scientist's most frequent publication venues include:

  • Diabetes Research and Clinical Practice
  • Internal and Emergency Medicine
  • Cardiovascular Diabetology
  • European Journal of Clinical Investigation
  • SN Comprehensive Clinical Medicine

Sesti's research encompasses several primary fields of study such as Medicine, with notable contributions in the subfields of:

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Surgery
  • Epidemiology

Main topics covered in their work include:

  • Cardiovascular Function and Risk Factors
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Liver Disease Diagnosis and Treatment
  • Cardiovascular Health and Disease Prevention
  • Diabetes Management and Research

Selected recent papers authored by or involving Giorgio Sesti are:

  • International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes, 2024, Diabetes Research and Clinical Practice
  • Review of methods for detecting glycemic disorders, 2020, Diabetes Research and Clinical Practice
  • Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity, 2020, International Journal of Molecular Sciences
  • Major cardiovascular events, heart failure, and atrial fibrillation in patients treated with glucagon-like peptide-1 receptor agonists: An updated meta-analysis of randomized controlled trials, 2020, Nutrition Metabolism and Cardiovascular Diseases
  • Impact of Mediterranean Diet on Disease Activity and Gut Microbiota Composition of Rheumatoid Arthritis Patients, 2020, Microorganisms

Frequent co-authors collaborating with Sesti include:

  • Angela Sciacqua
  • Francesco Andreozzi
  • Teresa Vanessa Fiorentino
  • Elena Succurro
  • Maria Perticone

Best Publications

  • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6).

    John B Buse;Julio Rosenstock;Giorgio Sesti;Wolfgang E Schmidt

  • Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

    Adrian F Hernandez;Jennifer B Green;Salim Janmohamed;Ralph B D'Agostino

  • Defects of the insulin receptor substrate (IRS) system in human metabolic disorders

    Giorgio Sesti;Massimo Federici;Marta L. Hribal;Davide Lauro

  • High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program

    Massimo Federici;Marta Hribal;Lucia Perego;Marco Ranalli

  • Insulin-Dependent Activation of Endothelial Nitric Oxide Synthase Is Impaired by O-Linked Glycosylation Modification of Signaling Proteins in Human Coronary Endothelial Cells

    Massimo Federici;Rossella Menghini;Alessandro Mauriello;Marta Letizia Hribal

  • Pathophysiology of insulin resistance

    Giorgio Sesti

  • Uric Acid and Endothelial Dysfunction in Essential Hypertension

    Carmine Zoccali;Raffaele Maio;Francesca Mallamaci;Giorgio Sesti

  • Asymmetric dimethylarginine, L-arginine, and endothelial dysfunction in essential hypertension.

    Francesco Perticone;Angela Sciacqua;Raffaele Maio;Maria Perticone

  • Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial

    Olga Vaccaro;Maria Masulli;Antonio Nicolucci;Enzo Bonora

  • Angiotensin II Impairs the Insulin Signaling Pathway Promoting Production of Nitric Oxide by Inducing Phosphorylation of Insulin Receptor Substrate-1 on Ser312 and Ser616 in Human Umbilical Vein Endothelial Cells

    Francesco Andreozzi;Emanuela Laratta;Angela Sciacqua;Francesco Perticone

  • Pulse pressure and endothelial dysfunction in never-treated hypertensive patients

    Roberto Ceravolo;Raffaele Maio;Arturo Pujia;Angela Sciacqua

  • A Phase 2, Randomized, Dose-Finding Study of the Novel Once-Weekly Human GLP-1 Analog, Semaglutide, Compared With Placebo and Open-Label Liraglutide in Patients With Type 2 Diabetes

    Michael A. Nauck;John R. Petrie;Giorgio Sesti;Edoardo Mannucci

  • Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

    Barbara Giovannone;Maria Lucia Scaldaferri;Massimo Federici;Ottavia Porzio

  • The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells.

    Ottavia Porzio;Massimo Federici;Marta Letizia Hribal;Davide Lauro

  • Switching to once-daily liraglutide from twice-daily exenatide further improves glycemic control in patients with type 2 diabetes using oral agents.

    John B. Buse;Giorgio Sesti;Wolfgang E. Schmidt;Eduard Montanya

  • Plasma Concentration of IGF-I Is Independently Associated With Insulin Sensitivity in Subjects With Different Degrees of Glucose Tolerance

    Giorgio Sesti;Angela Sciacqua;Marina Cardellini;Maria Adelaide Marini

  • Safety issues with glucagon-like peptide-1 receptor agonists (pancreatitis, pancreatic cancer and cholelithiasis): Data from randomized controlled trials.

    Matteo Monami;Besmir Nreu;Alessia Scatena;Barbara Cresci

  • Insulin Secretion in Metabolically Obese, but Normal Weight, and in Metabolically Healthy but Obese Individuals

    Elena Succurro;Maria A. Marini;Simona Frontoni;Marta L. Hribal

  • Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells.

    M J Quon;A J Butte;M J Zarnowski;G Sesti

  • Timp3 deficiency in insulin receptor–haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-α

    Massimo Federici;Marta L. Hribal;Rossella Menghini;Hiroko Kanno

Frequent Co-Authors

Massimo Federici
Massimo Federici University of Rome Tor Vergata
Stefano Del Prato
Stefano Del Prato University of Pisa
Franco Folli
Franco Folli University of Milan
Giovanni Tripepi
Giovanni Tripepi National Research Council (CNR)
Enzo Bonora
Enzo Bonora University of Verona
Angelo Avogaro
Angelo Avogaro University of Padua
Oluf Pedersen
Oluf Pedersen University of Copenhagen
Edoardo Mannucci
Edoardo Mannucci University of Florence
Giuseppe Paolisso
Giuseppe Paolisso University of Campania "Luigi Vanvitelli"
Francesco Violi
Francesco Violi Sapienza University of Rome

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