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Franco Folli

Franco Folli

D-Index & Metrics

Medicine

D-Index
79
Citations
23277
World Ranking
17545
National Ranking
711

Overview

Franco Folli is affiliated with the University of Milan in Italy and has contributed extensively to the field of Medicine, with a focus on Endocrinology, Diabetes and Metabolism, Pharmacology, Molecular Biology, Cellular and Molecular Neuroscience, and Surgery. Their research spans over 128 publications, with emphasis on diabetes and metabolic disorders.

The scientist's primary research topics cover multiple areas including:

  • Treatment of Major Depression
  • Diabetes Treatment and Management
  • Pancreatic function and diabetes
  • Metabolism, Diabetes, and Cancer
  • Diabetes and associated disorders
  • Diabetes Management and Research
  • Neuroscience and Neuropharmacology Research

Frequent co-authors in their collaborations include:

  • Paolo L. Manfredi (29 publications)
  • Sara De Martin (27 publications)
  • M. Pappagallo (25 publications)
  • Andrea Mattarei (25 publications)
  • Paolo Fiorina (21 publications)

Folli has published research in multiple specialized venues, regularly appearing in:

  • Pharmacological Research (7 publications)
  • American Journal of Physiology-Endocrinology and Metabolism (4 publications)
  • The Journal of Clinical Psychiatry (4 publications)
  • Acta Diabetologica (4 publications)
  • Diabetes (3 publications)

Selected recent papers demonstrate the range of their research impact and interests:

  • "Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule," 2024, Cell Metabolism
  • "Metformin acts in the gut and induces gut-liver crosstalk," 2023, Proceedings of the National Academy of Sciences
  • "Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection," 2021, Nature Metabolism
  • "REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial," 2021, American Journal of Psychiatry
  • "Sitagliptin Treatment at the Time of Hospitalization Was Associated With Reduced Mortality in Patients With Type 2 Diabetes and COVID-19: A Multicenter, Case-Control, Retrospective, Observational Study," 2020, Diabetes Care

Folli's work addresses multiple aspects of diabetes treatment and metabolic regulation, including the interplay between immune response mechanisms and diabetes, as well as neuropharmacological approaches in psychiatric disorders. The scientist's cross-disciplinary research approach also includes molecular and cellular investigations as well as clinical observations and case studies.

Best Publications

  • Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.

    Steinunn Baekkeskov;Henk-Jan Aanstoot;Stephan Christgai;Annette Reetz

  • Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases

    Teresa Vanessa Fiorentino;Annamaria Prioletta;Pengou Zuo;Franco Folli

  • Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome.

    Michele Solimena;Franco Folli;Roxanne Aparisi;Guido Pozza

  • Autoantibodies to Glutamic Acid Decarboxylase in a Patient with Stiff-Man Syndrome, Epilepsy, and Type I Diabetes Mellitus

    M. Solimena;F. Folli;S. Denis-Donini;G. C. Comi

  • Erratum: Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase (Nature (1990) 347 (151-156))

    Steinunn Baekkeskov;Henk Jan Aanstoot;Stephan Christgau;Annette Reetz

  • Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.

    F Folli;C R Kahn;H Hansen;J L Bouchie

  • Cross-talk between the insulin and angiotensin signaling systems.

    L. A. Velloso;F. Folli;X. J. Sun;M. F. White

  • GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion.

    A Reetz;M Solimena;M Matteoli;F Folli

  • High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program

    Massimo Federici;Marta Hribal;Lucia Perego;Marco Ranalli

  • Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance

    Alberto O. Chavez;Marjorie Molina-Carrion;Muhammad A. Abdul-Ghani;Franco Folli

  • The role of oxidative stress in the pathogenesis of type 2 diabetes mellitus micro- and macrovascular complications: avenues for a mechanistic-based therapeutic approach.

    Franco Folli;Domenico Corradi;Paolo Fanti;Alberto Davalli

  • Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats.

    M. J. A. Saad;F. Folli;J. A. Kahn;C. R. Kahn

  • Insulin and insulin-like growth factor-1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: differential effects on signal transduction pathways.

    G. Svegliati-Baroni;F. Ridolfi;A. Di Sario;A. Casini

  • Acute and long-term disruption of glycometabolic control after SARS-CoV-2 infection.

    Laura Montefusco;Moufida Ben Nasr;Moufida Ben Nasr;Francesca D'Addio;Cristian Loretelli

  • The synaptic vesicle-associated protein amphiphysin is the 128-kD autoantigen of Stiff-Man syndrome with breast cancer.

    P. De Camilli;A. Thomas;R. Cofiell;F. Folli

  • Autoantibodies to a 128-kd Synaptic Protein in Three Women with the Stiff-Man Syndrome and Breast Cancer

    F Folli;M Solimena;R Cofiell;M Austoni

  • Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies

    A B Goldfine;D C Simonson;F Folli;M E Patti

  • Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat.

    F. Folli;M. J. A. Saad;J. M. Backer;C. R. Kahn

  • The inflammatory status score including IL-6, TNF-α, osteopontin, fractalkine, MCP-1 and adiponectin underlies whole-body insulin resistance and hyperglycemia in type 2 diabetes mellitus

    G. Daniele;R. Guardado Mendoza;R. Guardado Mendoza;D. Winnier;T. V. Fiorentino;T. V. Fiorentino

  • Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus.

    F. Folli;M. J. A. Saad;J. M. Backer;C. R. Kahn

Frequent Co-Authors

Amalia Gastaldelli
Amalia Gastaldelli National Research Council (CNR)
Ralph A. DeFronzo
Ralph A. DeFronzo The University of Texas Health Science Center at San Antonio
Giorgio Sesti
Giorgio Sesti Sapienza University of Rome
Carlo Capella
Carlo Capella University of Insubria
Lício A. Velloso
Lício A. Velloso State University of Campinas
Mario J.A. Saad
Mario J.A. Saad State University of Campinas
Anthony G. Comuzzie
Anthony G. Comuzzie Obesity Society
Massimo Federici
Massimo Federici University of Rome Tor Vergata
Steinunn Baekkeskov
Steinunn Baekkeskov University of California, San Francisco

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