World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
83
Citations
33575
World Ranking
15411
National Ranking
7773

Overview

Jorge Plutzky is affiliated with Brigham and Women's Hospital in the United States and has made significant contributions to the field of medicine, focusing primarily on endocrinology, diabetes, metabolism, and cardiovascular medicine. With a publication record spanning multiple significant journals and topics, Plutzky's research addresses various aspects of cardiovascular health and diabetes treatment.

The scientist's recent papers include notable works such as:

  • "Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes" (2023), published in the New England Journal of Medicine
  • "Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients" (2023), New England Journal of Medicine
  • "Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity (SELECT) rationale and design" (2020), American Heart Journal
  • "Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial" (2024), Nature Medicine
  • "Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials" (2024), The Lancet

Plutzky's work prominently focuses on several main topics including:

  • Lipoproteins and Cardiovascular Health
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Pharmacology and Obesity Treatment
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Systemic Lupus Erythematosus Research
  • Cardiovascular Function and Risk Factors

Their research spans multiple subfields of study such as:

  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Molecular Biology
  • Rheumatology

Jorge Plutzky frequently publishes in several well-regarded journals and publication venues, including:

  • Journal of the American College of Cardiology
  • Circulation
  • Journal of the American Heart Association
  • American Heart Journal
  • JAMA Cardiology

The scientist collaborates with various frequent co-authors, which include:

  • Christopher P. Cannon
  • A. Michael Lincoff
  • Benjamin M. Scirica
  • Marcelo F. Di Carli
  • Ildiko Lingvay

Best Publications

  • Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus A scientific statement from the American Heart Association and the American Diabetes Association

    John B. Buse;Henry N. Ginsberg;George L. Bakris;Nathaniel G. Clark

  • Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

    U. Laufs;V. La Fata;J. Plutzky;J. K. Liao

  • International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

    Liliane Michalik;Johan Auwerx;Joel P. Berger;V. Krishna Chatterjee

  • Peroxisome Proliferator-Activated Receptor Gamma Activators Inhibit Gene Expression and Migration in Human Vascular Smooth Muscle Cells

    Nikolaus Marx;Uwe Schönbeck;Mitchell A. Lazar;Peter Libby

  • PPARα Activators Inhibit Cytokine-Induced Vascular Cell Adhesion Molecule-1 Expression in Human Endothelial Cells

    Nikolaus Marx;Galina K. Sukhova;Tucker Collins;Peter Libby

  • Macrophages in Human Atheroma Contain PPARγ: Differentiation-Dependent Peroxisomal Proliferator-Activated Receptor γ (PPARγ) Expression and Reduction of MMP-9 Activity through PPARγ Activation in Mononuclear Phagocytes in Vitro

    Nikolaus Marx;Galina Sukhova;Curran Murphy;Peter Libby

  • Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies.

    Theodore Mazzone;Alan Chait;Jorge Plutzky

  • Discontinuation of statins in routine care settings: a cohort study.

    Huabing Zhang;Jorge Plutzky;Stephen Skentzos;Fritha Morrison

  • NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

    Jonathan D. Brown;Charles Y. Lin;Qiong Duan;Qiong Duan;Gabriel Griffin

  • The Pathologic Continuum of Diabetic Vascular Disease

    Gabriela Orasanu;Jorge Plutzky

  • The Residual Risk Reduction Initiative: a call to action to reduce residual vascular risk in patients with dyslipidemia.

    Jean-Charles Fruchart;Frank Sacks;Michel P Hermans;Gerd Assmann

  • PPARγ Activation in Human Endothelial Cells Increases Plasminogen Activator Inhibitor Type-1 Expression PPARγ as a Potential Mediator in Vascular Disease

    Nikolaus Marx;Todd Bourcier;Galina K. Sukhova;Peter Libby

  • The Cardiovascular Disease Continuum Validated: Clinical Evidence of Improved Patient Outcomes Part I: Pathophysiology and Clinical Trial Evidence (Risk Factors Through Stable Coronary Artery Disease)

    Victor J. Dzau;Elliott M. Antman;Henry R. Black;David L. Hayes

  • PPAR Activators as Antiinflammatory Mediators in Human T Lymphocytes Implications for Atherosclerosis and Transplantation-Associated Arteriosclerosis

    Nikolaus Marx;Bettina Kehrle;Klaus Kohlhammer;Miriam Grüb

  • Peroxisome Proliferator–Activated Receptors as Transcriptional Nodal Points and Therapeutic Targets

    Jonathan D. Brown;Jorge Plutzky

  • Retinaldehyde represses adipogenesis and diet-induced obesity.

    Ouliana Ziouzenkova;Gabriela Orasanu;Molly Sharlach;Taro E Akiyama

  • Peroxisome Proliferator-Activated Receptor-γ Activators Inhibit IFN-γ-Induced Expression of the T Cell-Active CXC Chemokines IP-10, Mig, and I-TAC in Human Endothelial Cells

    Nikolaus Marx;François Mach;Alain Sauty;Josephine H. Leung

  • BET Bromodomains Mediate Transcriptional Pause Release in Heart Failure

    Priti Anand;Jonathan D. Brown;Charles Y. Lin;Jun Qi

  • Inflammatory pathways in atherosclerosis and acute coronary syndromes.

    Jorge Plutzky

  • Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: Evidence for an antiinflammatory role for lipoprotein lipase

    Ouliana Ziouzenkova;Stephane Perrey;Liana Asatryan;Juliana Hwang

Frequent Co-Authors

Christopher P. Cannon
Christopher P. Cannon Brigham and Women's Hospital
Peter Libby
Peter Libby Brigham and Women's Hospital
Marcelo F. Di Carli
Marcelo F. Di Carli Brigham and Women's Hospital
Ron Blankstein
Ron Blankstein Brigham and Women's Hospital
Henry N. Ginsberg
Henry N. Ginsberg Columbia University
Deepak L. Bhatt
Deepak L. Bhatt Mount Sinai Hospital
Khurram Nasir
Khurram Nasir Houston Methodist
Takashi Kadowaki
Takashi Kadowaki Toranomon Hospital
Calum A. MacRae
Calum A. MacRae Brigham and Women's Hospital
James E. Bradner
James E. Bradner Amgen (United States)

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