World's Best Scientists 2026 revealed!

Overview

Ching C. Lau is a researcher affiliated with Baylor College of Medicine in the United States with a focus on medicine and biochemistry, genetics, and molecular biology. Their body of work includes a strong emphasis on molecular biology, genetics, oncology, cancer research, and immunology.

The scientist has contributed extensively to cancer-related research, particularly in areas such as glioma diagnosis and treatment, epigenetics and DNA methylation, RNA modifications in cancer, and immunotherapy and immune responses. Their expertise also extends into CAR-T cell therapy research, neuroblastoma research and treatments, as well as cancer genomics and diagnostics.

Frequent publication venues for their work include Neuro-Oncology, where they have published the most, as well as Acta Neuropathologica, Cancer Letters, Evolution, and the International Journal of Molecular Sciences.

  • Xiao-Nan Li
  • Aaron Taylor
  • Joanna J. Gell
  • Nathaniel Jillette
  • Wan-Yee Teo

Among their recent papers are:

  • "Comparative Molecular Life History of Spontaneous Canine and Human Gliomas," 2020, Cancer Cell
  • "Immuno-transcriptomic profiling of extracranial pediatric solid malignancies," 2021, Cell Reports
  • "C11orf95-RELA reprograms 3D epigenome in supratentorial ependymoma," 2020, Acta Neuropathologica
  • "Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers," 2022, Stem Cell Reports
  • "Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression," 2024, Nature Communications

Best Publications

  • Prediction of central nervous system embryonal tumour outcome based on gene expression

    Scott L. Pomeroy;Pablo Tamayo;Michelle Gaasenbeek;Lisa M. Sturla

  • Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.

    Michele Ceccarelli;Floris P Barthel;Tathiane M Malta;Thais S Sabedot

  • Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer

    Matthew D. Burstein;Anna Tsimelzon;Graham M. Poage;Kyle R. Covington

  • Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial

    Amar Gajjar;Murali Chintagumpala;David Ashley;Stewart Kellie

  • Novel mutations target distinct subgroups of medulloblastoma

    Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu

  • Genome-wide association study identifies five susceptibility loci for glioma

    Sanjay Shete;Fay J. Hosking;Lindsay B. Robertson;Sara E. Dobbins

  • Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

    Xiaotu Ma;Yu Liu;Yanling Liu;Ludmil B. Alexandrov

  • Genomics Identifies Medulloblastoma Subgroups That Are Enriched for Specific Genetic Alterations

    Margaret C. Thompson;Christine Fuller;Twala L. Hogg;James Dalton

  • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.

    Yoon Jae Cho;Aviad Tsherniak;Pablo Tamayo;Sandro Santagata

  • Development of fuzzy algorithms for servo systems

    Y.F. Li;C.C. Lau

  • Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial

    Neyssa M Marina;Sigbjørn Smeland;Stefan S Bielack;Mark Bernstein

  • Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

    Sigbjørn Smeland;Stefan S. Bielack;Jeremy Whelan;Mark Bernstein

  • Mechanism by which caffeine potentiates lethality of nitrogen mustard

    Ching C. Lau;Arthur B. Pardee

  • Feeding Strategies for Premature Infants: Randomized Trial of Gastrointestinal Priming and Tube-feeding Method

    R J Schanler;R J Shulman;R J Shulman;C Lau;E O Smith

  • Clinical, Histopathologic, and Molecular Markers of Prognosis: Toward a New Disease Risk Stratification System for Medulloblastoma

    Amar Gajjar;Roberto Hernan;Mehmet Kocak;Christine Fuller

  • EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment

    J. S. Whelan;S. S. Bielack;N. Marina;S. Smeland

  • Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

    Beatrice S Melin;Jill S Barnholtz-Sloan;Margaret R Wrensch;Christoffer Johansen

  • Genome-wide association study of glioma and meta-analysis.

    Preetha Rajaraman;Beatrice S. Melin;Zhaoming Wang;Zhaoming Wang;Roberta McKean-Cowdin

  • Frequent Amplification of a chr19q13.41 MicroRNA Polycistron in Aggressive Primitive Neuroectodermal Brain Tumors

    Meihua Li;Kyle F. Lee;Yuntao Lu;Ian Clarke

  • Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC

    Xiao Nan Li;Qin Shu;Jack Men Feng Su;Laszlo Perlaky

Frequent Co-Authors

Richard S. Houlston
Richard S. Houlston Institute of Cancer Research
Paul S. Meltzer
Paul S. Meltzer National Institutes of Health
Francis Ali-Osman
Francis Ali-Osman Duke University
Richard A. Gibbs
Richard A. Gibbs Baylor College of Medicine
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Sharon E. Plon
Sharon E. Plon Baylor College of Medicine
David A. Wheeler
David A. Wheeler Baylor College of Medicine
Meredith Yeager
Meredith Yeager Hood College
Mark Lathrop
Mark Lathrop McGill University
Jeffrey C. Murray
Jeffrey C. Murray University of Iowa

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