World's Best Scientists 2026 revealed!
Francis Ali-Osman

Francis Ali-Osman

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
11056
World Ranking
12686
National Ranking
5407

Francis Ali-Osman publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Francis Ali-Osman sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 191 publications — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Francis Ali-Osman D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Francis Ali-Osman sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 59 D-Index — 38th percentile

38% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Francis Ali-Osman is affiliated with Duke University in the United States. Their research spans multiple areas within medicine, with a particular emphasis on surgery and genetics, as well as cancer research and hematology. The scientist's work intersects with emergency medicine and involves detailed studies in trauma management and diagnosis, spinal fractures and fixation techniques, and glioma diagnosis and treatment.

Francis Ali-Osman has authored several papers published in notable venues, including:

  • Outcome after surgical stabilization of rib fractures versus nonoperative treatment in patients with multiple rib fractures and moderate to severe traumatic brain injury (2020), published in The Journal of Trauma: Injury, Infection, and Critical Care
  • European genetic ancestry associated with risk of childhood ependymoma (2020), published in Neuro-Oncology
  • Surgical stabilization versus nonoperative treatment for flail and non-flail rib fracture patterns in patients with traumatic brain injury (2022), published in European Journal of Trauma and Emergency Surgery
  • A Phase II Trial of Imatinib Mesylate as Maintenance Therapy for Patients With Newly Diagnosed C-kit-positive Acute Myeloid Leukemia (2020), published in Clinical Lymphoma Myeloma & Leukemia
  • Proteomic profiling of patient-derived glioblastoma xenografts identifies a subset with activated EGFR: implications for drug development (2020), published in UNC Libraries

The scientist frequently collaborates with peers such as Jonne T.H. Prins, Esther M.M. Van Lieshout, Zachary M. Bauman, Eva-Corina Caragounis, and Jeff Choi. These co-authorships reflect an active engagement in multidisciplinary research teams.

Francis Ali-Osman's primary fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

The subfields of their research cover:

  • Surgery
  • Genetics
  • Cancer Research
  • Hematology
  • Emergency Medicine

The main topics that characterize Francis Ali-Osman's work are:

  • Trauma Management and Diagnosis
  • Spinal Fractures and Fixation Techniques
  • Glioma Diagnosis and Treatment
  • Trauma and Emergency Care Studies
  • Genetics and Neurodevelopmental Disorders
  • MicroRNA in disease regulation
  • Traumatic Ocular and Foreign Body Injuries

Best Publications

  • Molecular Cloning, Characterization, and Expression in Escherichia coli of Full-length cDNAs of Three Human Glutathione S-Transferase Pi Gene Variants EVIDENCE FOR DIFFERENTIAL CATALYTIC ACTIVITY OF THE ENCODED PROTEINS

    Francis Ali-Osman;Olanike Akande;Gamil Antoun;Jia-Xi Mao

  • Glutathione-associated cis-diamminedichloroplatinum(II) metabolism and ATP-dependent efflux from leukemia cells : molecular characterization of glutathione-platinum complex and its biological significance

    T Ishikawa;F Ali-Osman

  • Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.

    Tongxin Xie;Daoyan Wei;Mingguang Liu;Allen C. Gao

  • Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

    Beatrice S Melin;Jill S Barnholtz-Sloan;Margaret R Wrensch;Christoffer Johansen

  • Ubiquitination-Dependent Proteolysis of O6-Methylguanine-DNA Methyltransferase in Human and Murine Tumor Cells following Inactivation with O6-Benzylguanine or 1,3-Bis(2-chloroethyl)-1-nitrosourea†

    Kalkunte S. Srivenugopal;Xiao-Hua Yuan;Henry S. Friedman;Francis Ali-Osman

  • Genetic polymorphism and function of glutathione S-transferases in tumor drug resistance

    Hui-Wen Lo;Francis Ali-Osman

  • Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators.

    Hui-Wen Lo;Xinyu Cao;Hu Zhu;Francis Ali-Osman

  • Cyclooxygenase-2 Is a Novel Transcriptional Target of the Nuclear EGFR-STAT3 and EGFRvIII-STAT3 Signaling Axes

    Hui-Wen Lo;Xinyu Cao;Hu Zhu;Francis Ali-Osman

  • Germline mutations in shelterin complex genes are associated with familial glioma.

    Matthew N. Bainbridge;Georgina N. Armstrong;M. Monica Gramatges;Alison A. Bertuch

  • Selective Suppression of Matrix Metalloproteinase-9 in Human Glioblastoma Cells by Antisense Gene Transfer Impairs Glioblastoma Cell Invasion

    Sudha Kondraganti;Sanjeeva Mohanam;Shravan K. Chintala;Yoshiaki Kin

  • Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA.

    Jiang Shou;Francis Ali-Osman;Asha S Multani;Sen Pathak

  • Modulation of in Vitro Invasion of Human Glioblastoma Cells by Urokinase-type Plasminogen Activator Receptor Antibody

    Sanjeeva Mohanam;Raymond E Sawaya;Ian E McCutcheon;Francis Ali-Osman

  • A Novel Splice Variant of GLI1 That Promotes Glioblastoma Cell Migration and Invasion

    Hui-Wen Lo;Hu Zhu;Xinyu Cao;Amy Aldrich

  • Methylator Resistance Mediated by Mismatch Repair Deficiency in a Glioblastoma Multiforme Xenograft

    Henry S. Friedman;Stewart P. Johnson;Qing Dong;S. Clifford Schold

  • Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair–deficient malignant glioma xenograft

    C. Lynn Cheng;Stewart P. Johnson;Stephen T. Keir;Jennifer A. Quinn

  • Prognostic significance of glutathione S-transferase pi expression and subcellular localization in human gliomas.

    Francis Ali-Osman;Janet M. Brunner;Tetzer M. Kutluk;Kenneth Hess

  • Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage

    Ameya Paranjpe;Ruiwen Zhang;Francis Ali-Osman;George C. Bobustuc

  • Glutathione Content and Glutathione-S-transferase Expression in 1,3-Bis(2-chloroethyl)-1-nitrosourea-resistant Human Malignant Astrocytoma Cell Lines

    Francis Ali-Osman;Donna E. Stein;Alexander Renwick

  • Genomic and Molecular Profiling Predicts Response to Temozolomide in Melanoma

    Christina K. Augustine;Jin Soo Yoo;Anil Potti;Yasunori Yoshimoto

  • Approaching a Scientific Consensus on the Association between Allergies and Glioma Risk: A Report from the Glioma International Case-Control Study.

    E. Susan Amirian;Renke Zhou;Margaret R. Wrensch;Sara H. Olson

Frequent Co-Authors

Henry S. Friedman
Henry S. Friedman Duke University
Darell D. Bigner
Darell D. Bigner Duke University
Margaret R. Wrensch
Margaret R. Wrensch University of California, San Francisco
Melissa L. Bondy
Melissa L. Bondy Stanford University
Jill S. Barnholtz-Sloan
Jill S. Barnholtz-Sloan Case Western Reserve University
Raymond Sawaya
Raymond Sawaya The University of Texas MD Anderson Cancer Center
Joellen M. Schildkraut
Joellen M. Schildkraut University of Virginia
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Richard S. Houlston
Richard S. Houlston Institute of Cancer Research

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