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Biology and Biochemistry

D-Index
59
Citations
18506
World Ranking
12300
National Ranking
5262

Overview

Danyelle M. Townsend is affiliated with the Medical University of South Carolina in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on Molecular Biology, Biomedical Engineering, Biomaterials, Cell Biology, and Pharmacology.

The scientist's work covers multiple key topics including Genomics, phytochemicals, and oxidative stress; Glutathione Transferases and Polymorphisms; Nanoparticle-Based Drug Delivery; Bioactive Compounds and Antitumor Agents; Cancer therapeutics and mechanisms; Nanoplatforms for cancer theranostics; and Mitochondrial Function and Pathology.

Recent selected publications by Danyelle M. Townsend include:

  • The Multifaceted Role of Glutathione S-Transferases in Health and Disease, 2023, Biomolecules
  • Cisplatin chemotherapy and renal function, 2021, Advances in cancer research
  • Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model, 2020, Biomedicine & Pharmacotherapy
  • Recent advances in point of care testing for COVID-19 detection, 2022, Biomedicine & Pharmacotherapy
  • pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment, 2021, Biomedicine & Pharmacotherapy

Frequent collaborators in Townsend's research include Zhiwei Ye, Jie Zhang, Kenneth D. Tew, André Luís Branco de Barros, and Leilei Zhang.

Key publication venues for Townsend's work include Biomedicine & Pharmacotherapy, Advances in cancer research, Journal of Pharmacology and Experimental Therapeutics, Pharmaceutics, and Frontiers in Physiology.

Best Publications

  • The importance of glutathione in human disease.

    Danyelle M. Townsend;Kenneth D. Tew;Haim Tapiero

  • The role of glutathione-S-transferase in anti-cancer drug resistance

    Danyelle M Townsend;Kenneth D Tew

  • Trace elements in human physiology and pathology. Copper.

    H. Tapiero;D.M. Townsend;K.D. Tew

  • The antioxidant role of selenium and seleno-compounds

    H Tapiero;D M Townsend;K D Tew

  • The role of carotenoids in the prevention of human pathologies.

    H Tapiero;D M Townsend;K D Tew

  • Glutathione S-transferase polymorphisms: cancer incidence and therapy

    C C McIlwain;D M Townsend;K D Tew

  • Metabolism of Cisplatin to a Nephrotoxin in Proximal Tubule Cells

    Danyelle M. Townsend;Mei Deng;Lei Zhang;Maia G. Lapus

  • S-glutathionylation: from molecular mechanisms to health outcomes.

    Ying Xiong;Joachim D. Uys;Kenneth D. Tew;Danyelle M. Townsend

  • Novel Role for Glutathione S-Transferase π: REGULATOR OF PROTEIN S-GLUTATHIONYLATION FOLLOWING OXIDATIVE AND NITROSATIVE STRESS*

    Danyelle M. Townsend;Yefim Manevich;Lin He;Steven Hutchens

  • Causes and Consequences of Cysteine S-Glutathionylation *

    Christina L. Grek;Jie Zhang;Yefim Manevich;Danyelle M. Townsend

  • Alpha-tocopherol: roles in prevention and therapy of human disease.

    J.M. Tucker;D.M. Townsend

  • S-Glutathionylation: Indicator of Cell Stress and Regulator of the Unfolded Protein Response

    Danyelle M. Townsend

  • Oxidative stress, redox regulation and diseases of cellular differentiation.

    Zhi-Wei Ye;Jie Zhang;Danyelle M. Townsend;Kenneth D. Tew

  • Voltage-dependent Anion Channels Modulate Mitochondrial Metabolism in Cancer Cells REGULATION BY FREE TUBULIN AND ERASTIN

    Eduardo N. Maldonado;Kely L. Sheldon;Kely L. Sheldon;David N. DeHart;Jyoti Patnaik

  • The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer

    Kenneth D. Tew;Yefim Manevich;Christina Grek;Ying Xiong

  • Glutathione-S-Transferases As Determinants of Cell Survival and Death

    Kenneth D. Tew;Danyelle M. Townsend

  • Sulfur containing amino acids and human disease.

    Danyelle M Townsend;Kenneth D Tew;Haim Tapiero

  • A novel role for human sulfiredoxin in the reversal of glutathionylation.

    Victoria J. Findlay;Danyelle M. Townsend;Taylor E. Morris;Jacob P. Fraser

  • γ-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo

    Marie H. Hanigan;Betty C. Gallagher;Danyelle M. Townsend;Veronica Gabarra

  • Cancer Drugs, Genetic Variation and the Glutathione- S -Transferase Gene Family

    Danyelle M. Townsend;Kenneth D. Tew

Frequent Co-Authors

Kenneth D. Tew
Kenneth D. Tew Medical University of South Carolina
Yefim Manevich
Yefim Manevich Medical University of South Carolina
Domenico Rubello
Domenico Rubello University of Padua
John J. Lemasters
John J. Lemasters Medical University of South Carolina
Yvonne M. W. Janssen-Heininger
Yvonne M. W. Janssen-Heininger University of Vermont
Xinhua Ji
Xinhua Ji National Institutes of Health
Lina M. Obeid
Lina M. Obeid Stony Brook University
Carlos G. Dotti
Carlos G. Dotti Spanish National Research Council
Peter W. Kalivas
Peter W. Kalivas Medical University of South Carolina
Ralf Morgenstern
Ralf Morgenstern Karolinska Institute

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