World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
53
Citations
9401
World Ranking
13141
National Ranking
3463

Biology and Biochemistry

D-Index
56
Citations
9771
World Ranking
14572
National Ranking
6112

Overview

Xinhua Ji is affiliated with the National Institutes of Health in the United States and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans several subfields including Molecular Biology, Infectious Diseases, Surgery, Epidemiology, and Obstetrics and Gynecology.

Their research focuses on topics such as RNA and protein synthesis mechanisms, Helicobacter pylori-related gastroenterology studies, RNA research and splicing, HIV/AIDS drug development and treatment, biochemical and molecular research, veterinary medicine and infectious diseases, and RNA modifications and cancer.

Xinhua Ji has published articles in various scientific journals. Notable recent papers include:

  • Synergistic Inhibition of Drug-Resistant Colon Cancer Growth with PI3K/mTOR Dual Inhibitor BEZ235 and Nano-Emulsioned Paclitaxel via Reducing Multidrug Resistance and Promoting Apoptosis, 2021, International Journal of Nanomedicine
  • IFITM1, CD10, SMA, and h-caldesmon as a helpful combination in differential diagnosis between endometrial stromal tumor and cellular leiomyoma, 2021, BMC Cancer
  • Minimum inhibitory concentrations of commonly used antibiotics against Helicobacter Pylori: A multicenter study in South China, 2021, PLoS ONE
  • A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation, 2021, PLoS Biology
  • Dual-Target Inhibitors of the Folate Pathway Inhibit Intrinsically Trimethoprim-Resistant DfrB Dihydrofolate Reductases, 2020, ACS Medicinal Chemistry Letters

Frequent coauthors in Xinhua Ji's research include:

  • Genbin Shi
  • G. Shaw
  • Lixin Fan
  • Weilin Zhao
  • Lijuan Pang

Common publication venues for Xinhua Ji's work are:

  • Acta Crystallographica Section A Foundations and Advances
  • International Journal of Nanomedicine
  • BMC Cancer
  • PLoS ONE
  • PLoS Biology

Best Publications

  • Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.

    I. Sinning;G. J. Kleywegt;S. W. Cowan;P. Reinemer

  • The three-dimensional structure of a glutathione S-transferase from the mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-A resolution.

    Xinhua Ji;Pinghui Zhang;Richard N. Armstrong;Gary L. Gilliland

  • Crystallographic and Modeling Studies of RNase III Suggest a Mechanism for Double-Stranded RNA Cleavage

    Jaroslaw Blaszczyk;Joseph E. Tropea;Mikhail Bubunenko;Karen M. Routzahn

  • Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

    J. R. Stagno;Y. Liu;Y. R. Bhandari;C. E. Conrad

  • Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III

    Jianhua Gan;Joseph E. Tropea;Brian P. Austin;Donald L. Court

  • Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods.

    Xinhua Ji;E. C. Van Rosenvinge;W. W. Johnson;S. I. Tomarev

  • Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody.

    Ponraj Prabakaran;Jianhua Gan;Yang Feng;Zhongyu Zhu

  • Contribution of tyrosine 6 to the catalytic mechanism of isoenzyme 3-3 of glutathione S-transferase.

    Suxing Liu;Pinghui Zhang;Xinhua Ji;W. W. Johnson

  • JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.

    Paul J. Shami;Joseph E. Saavedra;Lai Y. Wang;Challice L. Bonifant

  • Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons.

    Xun Hu;Hong Xia;Sanjay K. Srivastava;Christian Herzog

  • Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIV

    Kap Lim;Joseph X. Ho;Kim Keeling;Gary L. Gilliland

  • Allosteric Activation of E2-RING Finger Mediated Ubiquitylation by a Structurally-Defined Specific E2 Binding Region of gp78

    Ranabir Das;Jennifer Mariano;Yien Che Tsai;Ravi C. Kalathur

  • Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA

    Jaroslaw Blaszczyk;Jianhua Gan;Joseph E Tropea;Donald L Court

  • RNase III: Genetics and Function; Structure and Mechanism.

    Donald L. Court;Jianhua Gan;Yu-He Liang;Gary X. Shaw

  • A stepwise model for double-stranded RNA processing by ribonuclease III.

    Jianhua Gan;Gary Shaw;Joseph E. Tropea;David S. Waugh

  • Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

    Paul J. Shami;Joseph E. Saavedra;Challice L. Bonifant;Jingxi Chu

  • Tyrosine 115 participates both in chemical and physical steps of the catalytic mechanism of a glutathione S-transferase.

    W. W. Johnson;Suxing Liu;Xinhua Ji;G. L. Gilliland

  • Tumor Cell Responses to a Novel Glutathione S-Transferase–Activated Nitric Oxide-Releasing Prodrug

    Victoria J. Findlay;Danyelle M. Townsend;Joseph E. Saavedra;Gregory S. Buzard

  • Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.

    Yijun Gu;Ludmila Reshetnikova;Yue Li;Yan Wu

  • Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.

    Xinhua Ji;William W. Johnson;Muctarr A. Sesay;Laura Dickert

  • Crystal structure of ERA: A GTPase-dependent cell cycle regulator containing an RNA binding motif

    Xin Chen;Donald L. Court;Xinhua Ji

Frequent Co-Authors

Gary L. Gilliland
Gary L. Gilliland National Institute of Standards and Technology
Shivendra V. Singh
Shivendra V. Singh University of Pittsburgh
David S. Waugh
David S. Waugh National Institutes of Health
Joseph E. Saavedra
Joseph E. Saavedra National Institutes of Health
Larry K. Keefer
Larry K. Keefer Science Applications International Corporation (United States)
Piotr Zimniak
Piotr Zimniak University of Arkansas for Medical Sciences
Richard N. Armstrong
Richard N. Armstrong Vanderbilt University
Christian Bogdan
Christian Bogdan University of Erlangen-Nuremberg
Donald L. Court
Donald L. Court National Institutes of Health
Petra Fromme
Petra Fromme Arizona State University

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