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Medicine

D-Index
121
Citations
49539
World Ranking
3629
National Ranking
2003

Overview

Lewis C. Becker is affiliated with the Johns Hopkins University School of Medicine in the United States. Their research spans across the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with specific focus on Genetics, Molecular Biology, Cardiology and Cardiovascular Medicine, Hematology, and Physiology.

The scientist's recent publications include work on large-scale genome sequencing and genetic epidemiology. Notable papers are:

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program (2021, Nature)
  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes (2020, Nature)
  • Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data (2022, Nature Genetics)
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale (2020, Nature Genetics)
  • Clonal haematopoiesis and risk of chronic liver disease (2023, Nature)

Their work addresses topics including Genetic Associations and Epidemiology, Genomics and Rare Diseases, Platelet Disorders and Treatments, Myeloproliferative Neoplasms: Diagnosis and Treatment, Acute Myeloid Leukemia Research, Telomeres, Telomerase, and Senescence, as well as Epigenetics and DNA Methylation.

Frequent co-authors in their research include Lisa R. Yanek, Eric Boerwinkle, Laura M. Raffield, Jennifer A. Brody, and Stephen S. Rich. These collaborations have contributed to a diverse range of studies within their areas of expertise.

Publication venues frequently featuring their work include UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Stroke, Nature Communications, and Nature. Their contributions have appeared extensively in these outlets, reflecting a broad engagement with both preprint and peer-reviewed scientific literature.

In addition to research articles, Lewis C. Becker has contributed to academic literature through book publications, including "Hamiltonian Systems," published by Cambridge University Press in 2024.

Best Publications

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

    Heribert Schunkert;Inke R. König;Sekar Kathiresan;Muredach P. Reilly

  • Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

    Gudmar Thorleifsson;G Bragi Walters;Daniel F Gudbjartsson;Valgerdur Steinthorsdottir

  • A Polymorphism of a Platelet Glycoprotein Receptor as an Inherited Risk Factor for Coronary Thrombosis

    Ethan J. Weiss;Paul F. Bray;Matthew Tayback;Steven P. Schulman

  • Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate.

    R J Rodeheffer;G Gerstenblith;L C Becker;J L Fleg

  • Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction.

    Barry A. Borlaug;Vojtech Melenovsky;Stuart D. Russell;Kristy Kessler

  • Many sequence variants affecting diversity of adult human height

    Daniel F Gudbjartsson;G Bragi Walters;Gudmar Thorleifsson;Hreinn Stefansson

  • Nitric oxide synthase in cardiac sarcoplasmic reticulum

    Kai Y. Xu;David L. Huso;Ted M. Dawson;David S. Bredt

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

    Alexander G Bick;Joshua S Weinstock;Satish K Nandakumar;Satish K Nandakumar;Charles P Fulco;Charles P Fulco

  • Two-dimensional echocardiography and infarct size: relationship of regional wall motion and thickening to the extent of myocardial infarction in the dog.

    A N Lieberman;J L Weiss;B I Jugdutt;L C Becker

  • Progressive impairment of regional myocardial perfusion after initial restoration of postischemic blood flow.

    Giuseppe Ambrosio;Harlan F. Weisman;John A. Mannisi;Lewis C. Becker

  • Magnitude and Time Course of Microvascular Obstruction and Tissue Injury After Acute Myocardial Infarction

    Carlos E. Rochitte;João A. C. Lima;David A. Bluemke;Scott B. Reeder

  • Physiological Basis of Myocardial Contrast Enhancement in Fast Magnetic Resonance Images of 2-Day-Old Reperfused Canine Infarcts

    Robert M. Judd;Carlos H. Lugo-Olivieri;Masazumi Arai;Takeshi Kondo

  • Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

    Daniel Taliun;Daniel N. Harris;Michael D. Kessler;Jedidiah Carlson;Jedidiah Carlson

  • Animal models for protecting ischemic myocardium: results of the NHLBI cooperative study. Comparison of unconscious and conscious dog models

    K. A. Reimer;R. B. Jennings;F. R. Cobb;R. H. Murdock

  • L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial.

    Steven P. Schulman;Lewis C. Becker;David A. Kass;Hunter C. Champion

  • Effect of Ischemia and Antianginal Drugs on the Distribution of Radioactive Microspheres in the Canine Left Ventricle

    Lewis C. Becker;Nicholas J. Fortuin;Bertram Pitt

  • Reduction in experimental infarct size by recombinant human superoxide dismutase: insights into the pathophysiology of reperfusion injury.

    G Ambrosio;L C Becker;G M Hutchins;H F Weisman

  • Quantification and time course of microvascular obstruction by contrast-enhanced echocardiography and magnetic resonance imaging following acute myocardial infarction and reperfusion

    Katherine C Wu;Raymond J Kim;David A Bluemke;Carlos E Rochitte

  • Myocardial Reperfusion Injury.

    Lewis C. Becker

Frequent Co-Authors

Diane M. Becker
Diane M. Becker Johns Hopkins University School of Medicine
Lisa R. Yanek
Lisa R. Yanek Johns Hopkins University School of Medicine
Dhananjay Vaidya
Dhananjay Vaidya Johns Hopkins University School of Medicine
Rasika A. Mathias
Rasika A. Mathias Johns Hopkins University
Gary Gerstenblith
Gary Gerstenblith Johns Hopkins University
Bernadine H. Bulkley
Bernadine H. Bulkley Johns Hopkins University
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Edward G. Lakatta
Edward G. Lakatta National Institutes of Health
Bruce M. Psaty
Bruce M. Psaty University of Washington
Alexander P. Reiner
Alexander P. Reiner University of Washington

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