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Biology and Biochemistry

D-Index
51
Citations
8677
World Ranking
17237
National Ranking
7093

Overview

Yefim Manevich is affiliated with the Medical University of South Carolina in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology as evident in their publication record.

The main research topics covered in their work include:

  • Redox biology and oxidative stress
  • DNA Repair Mechanisms
  • Glutathione Transferases and Polymorphisms
  • Genetic and Kidney Cyst Diseases
  • Mitochondrial Function and Pathology
  • Sulfur Compounds in Biology

Their recent publications demonstrate involvement in studying redox regulation and metabolic imbalances related to kidney disease and cellular oxidative processes. The most recent papers are:

  • "Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1," published in 2022 in Redox Biology
  • "Imbalances in mitochondrial metabolism and uncoupling protein 2 in policystic kidney disease cells," published in 2023 in Biophysical Journal

The venues where their research has frequently appeared include:

  • Redox Biology
  • Biophysical Journal

Yefim Manevich has collaborated with various researchers over the course of their studies. Frequent co-authors include:

  • John Skoko
  • Juxiang Cao
  • David Gaboriau
  • Myriam A. Attar
  • Alparslan Asan

Best Publications

  • Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism.

    Yefim Manevich;Aron B. Fisher

  • Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with πGST

    Y. Manevich;S. I. Feinstein;A. B. Fisher

  • Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity

    Juxiang Cao;Jennifer Schulte;Alexander Knight;Nicholas R Leslie

  • Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase.

    Aron B. Fisher;Chandra Dodia;Yefim Manevich;Jin-Wen Chen

  • Novel Role for Glutathione S-Transferase π: REGULATOR OF PROTEIN S-GLUTATHIONYLATION FOLLOWING OXIDATIVE AND NITROSATIVE STRESS*

    Danyelle M. Townsend;Yefim Manevich;Lin He;Steven Hutchens

  • Causes and Consequences of Cysteine S-Glutathionylation *

    Christina L. Grek;Jie Zhang;Yefim Manevich;Danyelle M. Townsend

  • Voltage-dependent Anion Channels Modulate Mitochondrial Metabolism in Cancer Cells REGULATION BY FREE TUBULIN AND ERASTIN

    Eduardo N. Maldonado;Kely L. Sheldon;Kely L. Sheldon;David N. DeHart;Jyoti Patnaik

  • The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer

    Kenneth D. Tew;Yefim Manevich;Christina Grek;Ying Xiong

  • Peroxiredoxin 1 and its role in cell signaling.

    Carola A. Neumann;Juxiang Cao;Yefim Manevich

  • 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage.

    Yefim Manevich;Tom Sweitzer;Jhang Ho Pak;Sheldon I. Feinstein

  • Direct evidence for the formation of a complex between 1-cysteine peroxiredoxin and glutathione S-transferase pi with activity changes in both enzymes.

    Luis A. Ralat;Yefim Manevich;and Aron B. Fisher;Roberta F. Colman

  • Coumarin-3-carboxylic acid as a detector for hydroxyl radicals generated chemically and by gamma radiation.

    Yefim Manevich;Kathryn D. Held;John E. Biaglow

  • Nitrosative stress-induced s-glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response

    Danyelle M. Townsend;Yefim Manevich;Lin He;Ying Xiong

  • Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network

    Can E. Senkal;Suriyan Ponnusamy;Yefim Manevich;Marisa Meyers-Needham

  • An Antisense Oligonucleotide to 1-cys Peroxiredoxin Causes Lipid Peroxidation and Apoptosis in Lung Epithelial Cells

    Jhang Ho Pak;Yefim Manevich;Han Suk Kim;Sheldon I. Feinstein

  • Lung injury and mortality with hyperoxia are increased in peroxiredoxin 6 gene-targeted mice.

    Yan Wang;Sheldon I. Feinstein;Yefim Manevich;Ye-Shih Ho

  • Transgenic Mice Overexpressing Peroxiredoxin 6 Show Increased Resistance to Lung Injury in Hyperoxia

    Yan Wang;Shelley A. Phelan;Yefim Manevich;Sheldon I. Feinstein

  • Peroxiredoxin 6 gene-targeted mice show increased lung injury with paraquat-induced oxidative stress.

    Yan Wang;Sheldon I. Feinstein;Yefim Manevich;Ye-Shih Ho

  • Nitration of the mitochondrial complex I subunit NDUFB8 elicits RIP1- and RIP3-mediated necrosis.

    Christiana W. Davis;Brian J. Hawkins;Subbiah Ramasamy;Krishna M. Irrinki;Krishna M. Irrinki

  • Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot permit commercial exploitation or the creation of derivative works without specific permission.

    Juxiang Cao;Jennifer Schulte;Alexander Knight;Nicholas R Leslie

Frequent Co-Authors

Aron B. Fisher
Aron B. Fisher University of Pennsylvania
Danyelle M. Townsend
Danyelle M. Townsend Medical University of South Carolina
Kenneth D. Tew
Kenneth D. Tew Medical University of South Carolina
Ye-Shih Ho
Ye-Shih Ho Wayne State University
John J. Lemasters
John J. Lemasters Medical University of South Carolina
Muniswamy Madesh
Muniswamy Madesh The University of Texas at Austin
Fatih M. Uckun
Fatih M. Uckun University of Southern California
Besim Ogretmen
Besim Ogretmen Medical University of South Carolina
Craig C. Beeson
Craig C. Beeson Medical University of South Carolina
Nick R. Leslie
Nick R. Leslie Heriot-Watt University

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