World's Best Scientists 2026 revealed!
Christine C. Winterbourn

Christine C. Winterbourn

Award Badge
Best Female Scientists
2025
Award Badge
Biology and Biochemistry
New Zealand
2026

D-Index & Metrics

Best Female Scientists

D-Index
112
Citations
46786
World Ranking
815
National Ranking
1

Chemistry

D-Index
105
Citations
42440
World Ranking
997
National Ranking
3

Biology and Biochemistry

D-Index
106
Citations
45558
World Ranking
1144
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in New Zealand Leader Award
  • 2026 - Research.com Chemistry in New Zealand Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Biology and Biochemistry in New Zealand Leader Award
  • 2025 - Research.com Chemistry in New Zealand Leader Award
  • 2023 - Research.com Biology and Biochemistry in New Zealand Leader Award
  • 2022 - Research.com Biology and Biochemistry in New Zealand Leader Award
  • 2022 - Research.com Chemistry in New Zealand Leader Award
  • 1988 - Fellow of the Royal Society of New Zealand

Overview

Christine C. Winterbourn is affiliated with the University of Otago in New Zealand and has a substantial publication record in the field of biochemistry, genetics, and molecular biology. Their work spans a range of subfields including molecular biology, immunology, biochemistry, nutrition and dietetics, and physiology.

Their research focuses primarily on redox biology and oxidative stress, with particular attention to neutrophil, myeloperoxidase, and oxidative mechanisms. Other significant research topics include sulfur compounds in biology, heat shock proteins, nitric oxide and endothelin effects, cell adhesion molecules, and glutathione transferases and polymorphisms.

Frequent venues for Winterbourn's publications include:

  • Free Radical Biology and Medicine
  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Redox Biology
  • Antioxidants

Winterbourn has collaborated extensively with several coauthors, notably:

  • Alexander V. Peskin
  • Paul Pace
  • Flávia Carla Meotti
  • Mark B. Hampton
  • Nicholas J. Magon

Selected recent papers include:

  • Hydrogen peroxide reactivity and specificity in thiol-based cell signalling, 2020, Biochemical Society Transactions
  • Biological chemistry of superoxide radicals, 2020, ChemTexts
  • Evaluating the bactericidal action of hypochlorous acid in culture media, 2020, Free Radical Biology and Medicine
  • Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology, 2022, Nature Reviews Molecular Cell Biology
  • Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo, 2022, Nature Metabolism

Christine C. Winterbourn was recognized as a Fellow of the Royal Society of New Zealand in 1988.

Best Publications

  • Reconciling the chemistry and biology of reactive oxygen species

    Christine C Winterbourn

  • Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

    Mark B. Hampton;Anthony J. Kettle;Christine C. Winterbourn

  • Toxicity of iron and hydrogen peroxide: the Fenton reaction.

    Unknown

  • Thiol chemistry and specificity in redox signaling.

    Christine C. Winterbourn;Mark B. Hampton

  • Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo

    Unknown

  • Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.

    Christine C. Winterbourn;Diana Metodiewa

  • Unraveling the biological roles of reactive oxygen species.

    Michael P. Murphy;Arne Holmgren;Nils Göran Larsson;Barry Halliwell

  • Reactive Oxygen Species and Neutrophil Function

    Christine C Winterbourn;Anthony J Kettle;Mark B Hampton

  • Myeloperoxidase: a key regulator of neutrophil oxidant production.

    A J Kettle;C C Winterbourn

  • Myeloperoxidase: a front-line defender against phagocytosed microorganisms

    Seymour J. Klebanoff;Anthony J. Kettle;Henry Rosen;Christine C. Winterbourn

  • Protein carbonyl measurement by a sensitive ELISA method.

    Unknown

  • Modeling the Reactions of Superoxide and Myeloperoxidase in the Neutrophil Phagosome: IMPLICATIONS FOR MICROBIAL KILLING*

    Christine C. Winterbourn;Mark B. Hampton;John H Livesey;Anthony J. Kettle

  • A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1)

    Alexander V Peskin;Christine C Winterbourn

  • Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling.

    Andrew G. Cox;Christine C. Winterbourn;Mark B. Hampton

  • The biological chemistry of hydrogen peroxide.

    Christine C Winterbourn

  • Redox reactions and microbial killing in the neutrophil phagosome.

    Christine C Winterbourn;Anthony J Kettle

  • The challenges of using fluorescent probes to detect and quantify specific reactive oxygen species in living cells.

    Christine C. Winterbourn

  • Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

    Heather Parker;Mike Dragunow;Mark B. Hampton;Anthony J. Kettle

  • Biomarkers of myeloperoxidase-derived hypochlorous acid.

    Christine C Winterbourn;Anthony J Kettle

  • Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite.

    Unknown

  • The High Reactivity of Peroxiredoxin 2 with H2O2 Is Not Reflected in Its Reaction with Other Oxidants and Thiol Reagents

    Alexander V. Peskin;Felicia M. Low;Louise N. Paton;Ghassan J. Maghzal

  • Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.

    Tessa J. Mocatta;Anna P. Pilbrow;Vicky A. Cameron;Revathy Senthilmohan

  • Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate.

    Alexander V Peskin;Christine C Winterbourn

  • Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils

    Neil M. Domigan;Timothy S. Charlton;Mark W. Duncan;Christine C. Winterbourn

Frequent Co-Authors

Anthony J. Kettle
Anthony J. Kettle University of Otago
Mark B. Hampton
Mark B. Hampton University of Otago
Terrie E. Inder
Terrie E. Inder Brigham and Women's Hospital
A. Mark Richards
A. Mark Richards National University of Singapore
Elias S.J. Arnér
Elias S.J. Arnér Karolinska Institute
Michael J. Davies
Michael J. Davies University of Copenhagen
John A. Windsor
John A. Windsor University of Auckland
Roland Stocker
Roland Stocker The Heart Research Institute
Michael P. Murphy
Michael P. Murphy University of Cambridge

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