D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 54 Citations 13,005 101 World Ranking 7085 National Ranking 2132
Biology and Biochemistry D-index 62 Citations 18,442 117 World Ranking 4815 National Ranking 2351

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Amino acid

His primary areas of investigation include Biochemistry, Cysteine, Peroxiredoxin, Sulfenic acid and Signal transduction. His Redox research extends to the thematically linked field of Biochemistry. His Cysteine research integrates issues from Thiol, Peroxidase, Catalytic cycle, Peptide sequence and Stereochemistry.

Leslie B. Poole has researched Peroxiredoxin in several fields, including Thioredoxin reductase, Oxidoreductase, Enzyme kinetics and Active site. His studies examine the connections between Signal transduction and genetics, as well as such issues in Cysteine metabolism, with regards to Kinase, Intracellular, Second messenger system and Dephosphorylation. In his study, which falls under the umbrella issue of Peroxiredoxin III, Sulfiredoxin is strongly linked to Peroxiredoxin-4.

His most cited work include:

  • Structure, mechanism and regulation of peroxiredoxins (2054 citations)
  • Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling (1087 citations)
  • Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes. (665 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Cysteine, Peroxiredoxin, Sulfenic acid and Peroxidase. His research on Biochemistry often connects related topics like Redox. The various areas that Leslie B. Poole examines in his Cysteine study include Oxidative damage, Thiol, Catalytic cycle, Stereochemistry and Protein structure.

Leslie B. Poole interconnects Active site, Peptide sequence, Cell biology, Thioredoxin and Peroxide in the investigation of issues within Peroxiredoxin. The Sulfenic acid study combines topics in areas such as Combinatorial chemistry, Reagent, Salt and Dimedone. Leslie B. Poole focuses mostly in the field of Peroxidase, narrowing it down to topics relating to Mutant and, in certain cases, Streptococcus mutans.

He most often published in these fields:

  • Biochemistry (54.79%)
  • Cysteine (42.02%)
  • Peroxiredoxin (29.79%)

What were the highlights of his more recent work (between 2014-2021)?

  • Biochemistry (54.79%)
  • Cell biology (15.96%)
  • Peroxiredoxin (29.79%)

In recent papers he was focusing on the following fields of study:

His main research concerns Biochemistry, Cell biology, Peroxiredoxin, Cysteine and Redox. In his research, Dithiol is intimately related to Stereochemistry, which falls under the overarching field of Biochemistry. Leslie B. Poole has included themes like Oxidative stress and Chondrocyte in his Cell biology study.

His Peroxiredoxin study combines topics in areas such as Mitogen-activated protein kinase and Xanthomonas campestris. His research in Cysteine is mostly focused on Sulfenic acid. His Peroxide research includes themes of Catalytic cycle and Hydrogen peroxide.

Between 2014 and 2021, his most popular works were:

  • The basics of thiols and cysteines in redox biology and chemistry (386 citations)
  • Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling. (264 citations)
  • Oxidative Stress Promotes Peroxiredoxin Hyperoxidation and Attenuates Pro-survival Signaling in Aging Chondrocytes (47 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Amino acid

Leslie B. Poole mostly deals with Biochemistry, Peroxiredoxin, Cysteine, Active site and Redox. His Peroxiredoxin research integrates issues from Oxidative stress, Cell signaling, Phylogenetic tree and Reactive oxygen species, Cell biology. His work carried out in the field of Cell biology brings together such families of science as Mutagenesis and Sulfiredoxin.

His work in Cysteine addresses issues such as Peroxide, which are connected to fields such as Hydrogen peroxide, Catalytic cycle and Sulfenic acid. His research integrates issues of Peroxidase, Stereochemistry and Oxidoreductase in his study of Active site. His studies in Redox integrate themes in fields like Biophysics and Thiol.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Structure, mechanism and regulation of peroxiredoxins

Zachary A Wood;Ewald Schröder;J Robin Harris;Leslie B Poole.
Trends in Biochemical Sciences (2003)

2673 Citations

Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling

Zachary A. Wood;Leslie B. Poole;P. Andrew Karplus.
Science (2003)

1409 Citations

Cloning and sequencing of thiol-specific antioxidant from mammalian brain: alkyl hydroperoxide reductase and thiol-specific antioxidant define a large family of antioxidant enzymes.

Ho Zoon Chae;Keith Robison;Leslie B. Poole;George Church.
Proceedings of the National Academy of Sciences of the United States of America (1994)

856 Citations

Protein Sulfenic Acids in Redox Signaling

Leslie B. Poole;P. Andrew Karplus;Al Claiborne.
Annual Review of Pharmacology and Toxicology (2004)

662 Citations

The basics of thiols and cysteines in redox biology and chemistry

Leslie B. Poole.
Free Radical Biology and Medicine (2015)

595 Citations

Typical 2-Cys Peroxiredoxins: Structures, mechanisms and functions

Andrea Hall;P. A. Karplus;Leslie B. Poole.
FEBS Journal (2009)

463 Citations

Discovering mechanisms of signaling-mediated cysteine oxidation

Leslie B Poole;Kimberly J Nelson.
Current Opinion in Chemical Biology (2008)

435 Citations

Dimers to doughnuts: redox-sensitive oligomerization of 2-cysteine peroxiredoxins.

Zachary A. Wood;Leslie B. Poole;Roy R. Hantgan;P. Andrew Karplus.
Biochemistry (2002)

382 Citations

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling.

Arden Perkins;Kimberly J. Nelson;Derek Parsonage;Leslie B. Poole.
Trends in Biochemical Sciences (2015)

347 Citations

Cysteine-based redox switches in enzymes.

Chananat Klomsiri;P. Andrew Karplus;Leslie B. Poole.
Antioxidants & Redox Signaling (2011)

329 Citations

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