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Chemistry

D-Index
47
Citations
7362
World Ranking
15707
National Ranking
3943

Overview

S. Bruce King is affiliated with Wake Forest University in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Their work spans subfields including Molecular Biology, Physiology, Biochemistry, Plant Science, and Cancer Research.

Their recent published papers cover a range of topics related to redox biology, sulfur compounds, and nitric oxide effects, reflecting a focus on biochemical signaling and physiological processes. Notable publications include:

  • "Nitroaromatic Antibiotics as Nitrogen Oxide Sources" (2021) in Biomolecules
  • "Introduction to approaches and tools for the evaluation of protein cysteine oxidation" (2020) in Essays in Biochemistry
  • "Discovery of endogenous nitroxyl as a new redox player in Arabidopsis thaliana" (2022) in Nature Plants
  • "[18F]Fluoro-DCP, a first generation PET radiotracer for monitoring protein sulfenylation in vivo" (2021) in Redox Biology
  • "Para-Substituted O-Benzyl Sulfohydroxamic Acid Derivatives as Redox-Triggered Nitroxyl (HNO) Sources" (2022) in Molecules

Their research has been published across several specialized venues, including Redox Biology, Biomolecules, Essays in Biochemistry, Nature Plants, and ACS Chemical Biology. S. Bruce King's collaboration network includes frequent co-authors such as Leslie B. Poole, Cristina M. Furdui, Allison M. Rice, Yueming Long, and Patricia C. Dos Santos.

The main topics of their research output consist of:

  • Nitric Oxide and Endothelin Effects
  • Sulfur Compounds in Biology
  • Cancer, Hypoxia, and Metabolism
  • Nanoplatforms for cancer theranostics
  • Bioactive Compounds and Antitumor Agents
  • Parasites and Host Interactions
  • Redox biology and oxidative stress

This body of work indicates an interdisciplinary approach connecting biochemical mechanisms with medical and biological applications, particularly in redox signaling and cancer-related pathways.

Best Publications

  • Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl

    Miriam M. Cortese-Krott;Gunter G. C. Kuhnle;Alex Dyson;Bernadette O. Fernandez

  • Acute effect of a high nitrate diet on brain perfusion in older adults

    Tennille D. Presley;Ashley R. Morgan;Erika Bechtold;William Clodfelter

  • Catalytic generation of N2O3 by the concerted nitrite reductase and anhydrase activity of hemoglobin.

    Swati Basu;Rozalina Grubina;Rozalina Grubina;Jinming Huang;Jeanet Conradie;Jeanet Conradie

  • Nitrite Reductase Activity of Cytochrome c

    Swati Basu;Natalia A. Azarova;Michael D. Font;S. Bruce King

  • Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins

    Leslie B. Poole;Chananat Klomsiri;Sarah A. Knaggs;Cristina M. Furdui

  • Hydrolysis of acyloxy nitroso compounds yields nitroxyl (HNO).

    Xin Sha;T. Scott Isbell;Rakesh P. Patel;Cynthia S. Day

  • Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species

    Revati Wani;Jiang Qian;Leimiao Yin;Erika Bechtold

  • Horseradish peroxidase catalyzed nitric oxide formation from hydroxyurea.

    Jinming Huang;Erin M Sommers;Daniel B Kim-Shapiro;S Bruce King

  • Nitric oxide production from hydroxyurea

    S.Bruce King

  • Use of dimedone-based chemical probes for sulfenic acid detection evaluation of conditions affecting probe incorporation into redox-sensitive proteins.

    Chananat Klomsiri;Kimberly J. Nelson;Erika Bechtold;Laura Soito

  • Synthesis of chemical probes to map sulfenic acid modifications on proteins.

    Leslie B. Poole;Bu-Bing Zeng;Sarah A. Knaggs;Mamudu Yakubu

  • Rapid and selective nitroxyl (HNO) trapping by phosphines: kinetics and new aqueous ligations for HNO detection and quantitation

    Julie A. Reisz;Charles N. Zink;S. Bruce King

  • Discriminating formation of HNO from other reactive nitrogen oxide species.

    Sonia Donzelli;Michael Graham Espey;Douglas D. Thomas;Daniele Mancardi

  • The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.

    Ryan D. Michalek;Kimberly J. Nelson;Beth C. Holbrook;John S. Yi

  • New Ligands and Improved Enantioselectivities for the Asymmetric Dihydroxylation of Olefins

    Heinrich Becker;S. Bruce King;Masahiko Taniguchi;Koenraad P. M. Vanhessche

  • Thiol-blocking electrophiles interfere with labeling and detection of protein sulfenic acids.

    Julie A. Reisz;Erika Bechtold;S. Bruce King;Leslie B. Poole

  • Potential biological chemistry of hydrogen sulfide (H2S) with the nitrogen oxides.

    S. Bruce King

  • Strained cycloalkynes as new protein sulfenic acid traps.

    Thomas H. Poole;Julie A. Reisz;Weiling Zhao;Leslie B. Poole

  • Reductive Phosphine-Mediated Ligation of Nitroxyl (HNO)

    Julie A Reisz;Erika B Klorig;Marcus W Wright;S Bruce King

  • Plasma nitrate and nitrite are increased by a high-nitrate supplement but not by high-nitrate foods in older adults.

    Gary D. Miller;Anthony P. Marsh;Robin W. Dove;Daniel Beavers

Frequent Co-Authors

Leslie B. Poole
Leslie B. Poole Wake Forest University
Mark T. Gladwin
Mark T. Gladwin University of Pittsburgh
Neil Hogg
Neil Hogg Medical College of Wisconsin
David A. Wink
David A. Wink National Institutes of Health
Ming Xian
Ming Xian Brown University
Katrina M. Miranda
Katrina M. Miranda University of Arizona
Jennifer E. Van Eyk
Jennifer E. Van Eyk Cedars-Sinai Medical Center
Giuseppe Lazzarino
Giuseppe Lazzarino University of Catania
Dennis J. Stuehr
Dennis J. Stuehr Cleveland Clinic Lerner College of Medicine
Viacheslav O. Nikolaev
Viacheslav O. Nikolaev Universität Hamburg

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