World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
27260
World Ranking
3657
National Ranking
1822

Overview

Sruti Shiva is affiliated with the University of Pittsburgh in the United States and has contributed significantly to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields including Molecular Biology, Genetics, Cardiology and Cardiovascular Medicine, Pulmonary and Respiratory Medicine, and Physiology.

Their work focuses on topics such as Mitochondrial Function and Pathology, Hemoglobinopathies and Related Disorders, Adipose Tissue and Metabolism, Heme Oxygenase-1 and Carbon Monoxide, Cardiovascular Function and Risk Factors, Pulmonary Hypertension Research and Treatments, and Cardiovascular Effects of Exercise.

Among their recent papers are:

  • Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement (2020) published in Redox Biology
  • Metabolic Syndrome Mediates ROS-miR-193b-NFYA-Dependent Downregulation of Soluble Guanylate Cyclase and Contributes to Exercise-Induced Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction (2021) published in Circulation
  • Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease (2022) published in Cell Stem Cell
  • Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic fitness (2020) published in The FASEB Journal
  • A blood-based marker of mitochondrial DNA damage in Parkinson's disease (2023) published in Science Translational Medicine

Sruti Shiva's frequent co-authors include:

  • Gowtham K. Annarapu
  • Michael Reynolds
  • Krithika Rao
  • Adam C. Straub
  • Deirdre Nolfi-Donegan

They have published extensively in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Free Radical Biology and Medicine
  • Blood
  • Research Square (Research Square)
  • Redox Biology

Best Publications

  • Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

    Donald G. Phinney;Michelangelo Di Giuseppe;Joel Njah;Ernest Sala

  • Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement.

    Deirdre Nolfi-Donegan;Andrea Braganza;Sruti Shiva

  • Nitrate and nitrite in biology, nutrition and therapeutics

    Jon O Lundberg;Mark T Gladwin;Amrita Ahluwalia;Nigel Benjamin

  • The emerging biology of the nitrite anion

    Mark T Gladwin;Alan N Schechter;Daniel B Kim-Shapiro;Rakesh P Patel

  • Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy

    Jason J. Rose;Ling Wang;Qinzi Xu;Charles F. McTiernan

  • Deoxymyoglobin is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration

    Sruti Shiva;Zhi Huang;Rozalina Grubina;Junhui Sun

  • Mitochondrial Reactive Oxygen Species Induces NLRP3-Dependent Lysosomal Damage and Inflammasome Activation

    Michelle E. Heid;Peter A. Keyel;Christelle Kamga;Sruti Shiva

  • Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer

    Sruti Shiva;Michael N. Sack;James J. Greer;Mark Duranski

  • PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

    Marta Bueno;Yen-Chun Lai;Yair Romero;Judith Brands

  • Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control.

    Zhi Huang;Sruti Shiva;Daniel B. Kim-Shapiro;Rakesh P. Patel

  • Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation

    Jack H. Crawford;T. Scott Isbell;T. Scott Isbell;T. Scott Isbell;Zhi Huang;Zhi Huang;Zhi Huang;Sruti Shiva;Sruti Shiva;Sruti Shiva

  • Nitrite as regulator of hypoxic signaling in mammalian physiology

    Ernst E. van Faassen;Soheyl Bahrami;Martin Feelisch;Neil Hogg

  • Nitrite reductase activity of myoglobin regulates respiration and cellular viability in myocardial ischemia-reperfusion injury.

    Ulrike B. Hendgen-Cotta;Marc W. Merx;Sruti Shiva;Joel Schmitz

  • Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

    Jesús Tejero;Sruti Shiva;Mark T. Gladwin

  • Ceruloplasmin is a NO oxidase and nitrite synthase that determines endocrine NO homeostasis

    Sruti Shiva;Xunde Wang;Lorna A Ringwood;Xueying Xu

  • Erythrocytes are the major intravascular storage sites of nitrite in human blood.

    Andre Dejam;Christian J Hunter;Mildred M Pelletier;Lewis L Hsu

  • Lipotoxicity Causes Multisystem Organ Failure and Exacerbates Acute Pancreatitis in Obesity

    Sarah Navina;Chathur Acharya;James P. DeLany;Lidiya S. Orlichenko

  • Platelet activation in patients with sickle disease, hemolysis-associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin

    José Villagra;Sruti Shiva;Lori A. Hunter;Roberto F. Machado

  • Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation

    Mark T. Gladwin;Nicolaas J. H. Raat;Sruti Shiva;Cameron Dezfulian

  • Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species.

    Paul S. Brookes;Anna-Liisa Levonen;Sruti Shiva;Paolo Sarti

Frequent Co-Authors

Mark T. Gladwin
Mark T. Gladwin University of Pittsburgh
Claudette M. St. Croix
Claudette M. St. Croix University of Pittsburgh
Neil Hogg
Neil Hogg Medical College of Wisconsin
Mauricio Rojas
Mauricio Rojas University of Pittsburgh
Victor M. Darley-Usmar
Victor M. Darley-Usmar University of Alabama at Birmingham
Shivendra V. Singh
Shivendra V. Singh University of Pittsburgh
Bruce A. Freeman
Bruce A. Freeman University of Pittsburgh
Malte Kelm
Malte Kelm Heinrich Heine University Düsseldorf
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Michael N. Sack
Michael N. Sack National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Sruti Shiva

Trending Scientists

Recently Published Articles