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Claudette M. St. Croix

Claudette M. St. Croix

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
15170
World Ranking
13011
National Ranking
5546

Overview

Claudette M. St. Croix is affiliated with the University of Pittsburgh in the United States and has concentrated their research efforts primarily within the fields of Medicine, and Biochemistry, Genetics and Molecular Biology. Their work also extensively covers subfields such as Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Immunology, and Physiology.

The scientist's research spans a variety of interconnected topics. Notable among these are ferroptosis and cancer prognosis, RNA modifications and cancer, mitochondrial function and pathology, cancer, lipids, and metabolism, pulmonary hypertension research and treatments, epigenetics and DNA methylation, and neonatal respiratory health research.

Several main publication venues have documented their research contributions. These include bioRxiv (Cold Spring Harbor Laboratory), Redox Biology, JCI Insight, Proceedings of the National Academy of Sciences, and The FASEB Journal, indicating a broad presence in both preprint and peer-reviewed journals.

Frequent collaborators in Claudette M. St. Croix's research network include:

  • Simon C. Watkins
  • Valerian E. Kagan
  • Yulia Y. Tyurina
  • Hülya Bayır
  • Alexandr A. Kapralov

The scientist's recent publications showcase a focus on cellular death mechanisms and disease processes. Selected papers include:

  • "Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death," 2020, Nature Chemical Biology
  • "Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes," 2021, Redox Biology
  • "PLA2G6 guards placental trophoblasts against ferroptotic injury," 2020, Proceedings of the National Academy of Sciences
  • "Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD," 2022, Autophagy
  • "Severe Acute Respiratory Syndrome Coronavirus 2 Viremia Is Associated With Coronavirus Disease 2019 Severity and Predicts Clinical Outcomes," 2021, Clinical Infectious Diseases

Best Publications

  • Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

    Valerian E Kagan;Gaowei Mao;Feng Qu;Jose Pedro Friedmann Angeli

  • Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs

    Donald G. Phinney;Michelangelo Di Giuseppe;Joel Njah;Ernest Sala

  • PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals

    Sally E. Wenzel;Yulia Y. Tyurina;Jinming Zhao;Claudette M. St. Croix

  • PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis

    Marta Bueno;Yen-Chun Lai;Yair Romero;Judith Brands

  • Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death.

    Alexandr A Kapralov;Qin Yang;Haider H Dar;Yulia Y Tyurina

  • NF-κB inhibition delays DNA damage–induced senescence and aging in mice

    Jeremy S. Tilstra;Andria R. Robinson;Jin Wang;Siobhán Q. Gregg

  • Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein

    Claudette M. St. Croix;K. J. Wasserloos;K. E. Dineley;I. J. Reynolds

  • Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium

    Haider H. Dar;Yulia Y. Tyurina;Karolina Mikulska-Ruminska;Karolina Mikulska-Ruminska;Indira Shrivastava

  • Impaired clearance and enhanced pulmonary inflammatory/fibrotic response to carbon nanotubes in myeloperoxidase-deficient mice.

    Anna A. Shvedova;Alexandr A. Kapralov;Wei Hong Feng;Elena R. Kisin

  • NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

    V. E. Kagan;J. Jiang;Z. Huang;Y. Y. Tyurina

  • A genetically targetable near-infrared photosensitizer

    Jianjun He;Yi Wang;Maria A Missinato;Ezenwa Onuoha

  • Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration.

    Luigi A. Nasto;Andria R. Robinson;Kevin Ngo;Cheryl L. Clauson

  • 15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells

    Jinming Zhao;Valerie Bridget O'Donnell;Silvana Balzar;Claudette M. St. Croix

  • Conjugated Linoleic Acid Is a Preferential Substrate for Fatty Acid Nitration

    Gustavo Bonacci;Paul R.S. Baker;Sonia R. Salvatore;Darla Shores

  • Lung macrophages "digest" carbon nanotubes using a superoxide/peroxynitrite oxidative pathway.

    Valerian E. Kagan;Alexandr A. Kapralov;Claudette M. St. Croix;Simon C. Watkins

  • Rapid Host Defense against Aspergillus fumigatus Involves Alveolar Macrophages with a Predominance of Alternatively Activated Phenotype

    Shikha Bhatia;Mingjian Fei;Manohar Yarlagadda;Zengbiao Qi

  • Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes.

    Sehwan Jang;Xavier R. Chapa-Dubocq;Yulia Y. Tyurina;Claudette M. St Croix

  • Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration

    A. Sahu;H. Mamiya;S. N. Shinde;A. Cheikhi

  • PLA2G6 guards placental trophoblasts against ferroptotic injury.

    Ofer Beharier;Vladimir A Tyurin;Julie P Goff;Jennifer Guerrero-Santoro

  • Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.

    Andria R. Robinson;Matthew J. Yousefzadeh;Tania A. Rozgaja;Jin Wang

Frequent Co-Authors

Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Bruce R. Pitt
Bruce R. Pitt University of Pittsburgh
Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Sruti Shiva
Sruti Shiva University of Pittsburgh
Yulia Y. Tyurina
Yulia Y. Tyurina University of Pittsburgh
Vladimir A. Tyurin
Vladimir A. Tyurin University of Pittsburgh
Hülya Bayır
Hülya Bayır University of Pittsburgh
Janet S. Lee
Janet S. Lee University of Pittsburgh
Donna B. Stolz
Donna B. Stolz University of Pittsburgh
Rama K. Mallampalli
Rama K. Mallampalli The Ohio State University

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