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83
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29339
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3456
National Ranking
1741

Overview

Vladimir A. Tyurin is affiliated with the University of Pittsburgh in the United States and has a significant research output focusing mainly on biochemistry, genetics, molecular biology, and medicine. Their work spans several specialized subfields, including molecular biology, pulmonary and respiratory medicine, immunology, cancer research, and oncology.

The scientist's research prominently addresses various biochemical and molecular mechanisms underlying disease processes, with a particular emphasis on ferroptosis, cancer prognosis, and immune cell function within cancer contexts. Other topics covered in their work include RNA modifications in cancer, lipid metabolism in relation to cancer, mitochondrial function and pathology, ATP synthase and ATPases research, as well as epigenetics and DNA methylation.

The frequent publication venues where Vladimir A. Tyurin's studies appear include:

  • Redox Biology
  • JCI Insight
  • Proceedings of the National Academy of Sciences
  • SSRN Electronic Journal
  • Nature Chemical Biology

Recent publications illustrating the scope of their research include:

  • "Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death" (2020, Nature Chemical Biology)
  • "Ferroptosis of tumour neutrophils causes immune suppression in cancer" (2022, Nature)
  • "Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal" (2021, Nature Chemical Biology)
  • "Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1" (2021, Nature Communications)
  • "Reactivation of dormant tumor cells by modified lipids derived from stress-activated neutrophils" (2020, Science Translational Medicine)

Collaboration is a notable aspect of their career, with frequent co-authors including Valerian E. Kagan, Yulia Y. Tyurina, Hülya Bayır, Alexandr A. Kapralov, and Svetlana N. Samovich, reflecting ongoing partnerships with researchers who share interests in ferroptosis, lipid metabolism, and cancer biology.

Best Publications

  • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

    Jose Pedro Friedmann Angeli;Manuela Schneider;Bettina Proneth;Yulia Y. Tyurina

  • Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

    Valerian E Kagan;Gaowei Mao;Feng Qu;Jose Pedro Friedmann Angeli

  • Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

    Valerian E Kagan;Vladimir A Tyurin;Jianfei Jiang;Yulia Y Tyurina

  • Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

    Charleen T. Chu;Jing Ji;Ruben K. Dagda;Jian Fei Jiang

  • PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals

    Sally E. Wenzel;Yulia Y. Tyurina;Jinming Zhao;Claudette M. St. Croix

  • Lipid accumulation and dendritic cell dysfunction in cancer

    Donna L. Herber;Wei Cao;Yulia Nefedova;Sergey V. Novitskiy

  • Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: role of iron.

    V.E. Kagan;Y.Y. Tyurina;V.A. Tyurin;N.V. Konduru

  • Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death.

    Alexandr A Kapralov;Qin Yang;Haider H Dar;Yulia Y Tyurina

  • Fatty acid transport protein 2 reprograms neutrophils in cancer

    Filippo Veglia;Vladimir A. Tyurin;Maria Blasi;Alessandra De Leo

  • Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

    Valerian E. Kagan;Hülya A. Bayır;Natalia A. Belikova;Olexandr Kapralov

  • Peroxidase activity and structural transitions of cytochrome c bound to cardiolipin-containing membranes.

    Natalia A. Belikova;Yury A. Vladimirov;Anatoly N. Osipov;Alexandr A. Kapralov

  • Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine.

    Valerian E. Kagan;Grigory G. Borisenko;Yulia Y. Tyurina;Yulia Y. Tyurina;Vladimir A. Tyurin;Vladimir A. Tyurin

  • A role for oxidative stress in apoptosis: oxidation and externalization of phosphatidylserine is required for macrophage clearance of cells undergoing Fas-mediated apoptosis.

    Valerian E. Kagan;Bettina Gleiss;Yulia Y. Tyurina;Vladimir A. Tyurin

  • Oxidative stress following traumatic brain injury in rats: quantitation of biomarkers and detection of free radical intermediates.

    Vladimir A. Tyurin;Yulia Y. Tyurina;Grigory G. Borisenko;Tatiana V. Sokolova

  • Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury

    Jing Ji;Anthony E Kline;Andrew Amoscato;Alejandro K Samhan-Arias

  • Assessment of Antioxidant Reserves and Oxidative Stress in Cerebrospinal Fluid after Severe Traumatic Brain Injury in Infants and Children

    Hülya Bayir;Hülya Bayir;Valerian E Kagan;Yulia Y Tyurina;Vladimir Tyurin

  • Iron catalysis of lipid peroxidation in ferroptosis: Regulated enzymatic or random free radical reaction?

    D.A. Stoyanovsky;Y.Y. Tyurina;I. Shrivastava;I. Bahar

  • Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

    Filippo Veglia;Vladimir A. Tyurin;Dariush Mohammadyani;Dariush Mohammadyani;Maria Blasi

  • Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis.

    Valerian E. Kagan;James P. Fabisiak;Anna A. Shvedova;Yulia Y. Tyurina

  • Phospholipase iPLA2β Averts Ferroptosis By Eliminating A Redox Lipid Death Signal

    Wan-Yang Sun;Vladimir A Tyurin;Karolina Mikulska-Ruminska;Indira H Shrivastava

Frequent Co-Authors

Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Yulia Y. Tyurina
Yulia Y. Tyurina University of Pittsburgh
Hülya Bayır
Hülya Bayır University of Pittsburgh
Andrew A. Amoscato
Andrew A. Amoscato University of Pittsburgh
Anna A. Shvedova
Anna A. Shvedova National Institute for Occupational Safety and Health
Joel S. Greenberger
Joel S. Greenberger University of Pittsburgh
Bruce R. Pitt
Bruce R. Pitt University of Pittsburgh
Patrick M. Kochanek
Patrick M. Kochanek University of Pittsburgh
Simon C. Watkins
Simon C. Watkins University of Pittsburgh
Judith Klein-Seetharaman
Judith Klein-Seetharaman Arizona State University

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