D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 101 Citations 38,596 466 World Ranking 640 National Ranking 412

Research.com Recognitions

Awards & Achievements

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Internal medicine

Valerian E. Kagan mainly focuses on Biochemistry, Cell biology, Oxidative stress, Lipid peroxidation and Antioxidant. His study looks at the intersection of Biochemistry and topics like Pharmacology with Ischemia. His study in Cell biology is interdisciplinary in nature, drawing from both Apoptosis, Programmed cell death and Phosphatidylserine.

Valerian E. Kagan combines subjects such as Inflammation, Glutathione and Nitric oxide with his study of Oxidative stress. His studies deal with areas such as Anesthesia and Radical as well as Antioxidant. His Mitochondrion research incorporates themes from Autophagy, Cytochrome, Reactive oxygen species and Cardiolipin.

His most cited work include:

  • Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease (1069 citations)
  • Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice (1059 citations)
  • Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors (913 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Biochemistry, Lipid peroxidation, Cell biology, Antioxidant and Oxidative stress. His study in Cardiolipin, Mitochondrion, Membrane, Oxidative phosphorylation and Radical falls under the purview of Biochemistry. In his study, Peroxidase and Cytochrome is strongly linked to Cytochrome c, which falls under the umbrella field of Cardiolipin.

His Lipid peroxidation study combines topics in areas such as Endoplasmic reticulum, Phospholipid and Pharmacology. His Cell biology research is multidisciplinary, incorporating elements of Apoptosis, Programmed cell death and Macrophage. His Oxidative stress study integrates concerns from other disciplines, such as Glutathione and Nitric oxide.

He most often published in these fields:

  • Biochemistry (40.49%)
  • Lipid peroxidation (27.89%)
  • Cell biology (21.85%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cell biology (21.85%)
  • Cardiolipin (14.27%)
  • Biochemistry (40.49%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Cardiolipin, Biochemistry, Mitochondrion and Programmed cell death. His Cell biology study combines topics from a wide range of disciplines, such as GPX4, Apoptosis and Phospholipid. Valerian E. Kagan interconnects Reactive oxygen species, Biophysics, Cytochrome c and Inner mitochondrial membrane in the investigation of issues within Cardiolipin.

His Biochemistry study frequently draws parallels with other fields, such as Redox. The Programmed cell death study combines topics in areas such as Cancer cell, Inflammation, Cell and Phosphatidylethanolamine. Lipid peroxidation is a subfield of Oxidative stress that Valerian E. Kagan investigates.

Between 2012 and 2021, his most popular works were:

  • Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease (1069 citations)
  • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice (748 citations)
  • ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition (530 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Internal medicine

Valerian E. Kagan focuses on Cell biology, Biochemistry, Cardiolipin, Mitochondrion and Programmed cell death. His research in Cell biology intersects with topics in Apoptosis, Phospholipid and Immunology. His Cardiolipin research incorporates elements of Translocase of the inner membrane, Lung injury, Inner mitochondrial membrane and Fatty acid.

His Mitochondrion research is multidisciplinary, incorporating perspectives in Lipid signaling, Kidney metabolism, Cardiolipins, Cytochrome and Mitophagy. His Cytochrome research is multidisciplinary, relying on both Peroxidase, Cytochrome c and Stereochemistry. Within one scientific family, Valerian E. Kagan focuses on topics pertaining to GPX4 under Programmed cell death, and may sometimes address concerns connected to Lipid peroxidation, Coenzyme Q10, Lipoxygenase and Kidney.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice

Anna A. Shvedova;Elena R. Kisin;Robert Mercer;Ashley R. Murray.
American Journal of Physiology-lung Cellular and Molecular Physiology (2005)

1517 Citations

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Brent R. Stockwell;José Pedro Friedmann Angeli;Hülya Bayir;Ashley I. Bush.
Cell (2017)

1294 Citations

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

Valerian E Kagan;Vladimir A Tyurin;Jianfei Jiang;Yulia Y Tyurina.
Nature Chemical Biology (2005)

1250 Citations

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

Jose Pedro Friedmann Angeli;Manuela Schneider;Bettina Proneth;Yulia Y. Tyurina.
Nature Cell Biology (2014)

911 Citations

The role of lipid peroxidation in pathogenesis of ischemic damage and the antioxidant protection of the heart.

F. Z. Meerson;F. Z. Meerson;V. E. Kagan;V. E. Kagan;Yu. P. Kozlov;Yu. P. Kozlov;L. M. Belkina;L. M. Belkina.
Basic Research in Cardiology (1982)

743 Citations

Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol.

Elena Serbinova;Valerian Kagan;Derick Han;Lester Packer.
Free Radical Biology and Medicine (1991)

735 Citations

Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation

Valerian E. Kagan;Nagarjun V. Konduru;Weihong Feng;Brett L. Allen.
Nature Nanotechnology (2010)

715 Citations

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

Anna A. Shvedova;Elena R. Kisin;Ashley R. Murray;Victor J Johnson.
American Journal of Physiology-lung Cellular and Molecular Physiology (2008)

682 Citations

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

Charleen T. Chu;Jing Ji;Ruben K. Dagda;Jian Fei Jiang.
Nature Cell Biology (2013)

665 Citations

Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: role of iron.

V.E. Kagan;Y.Y. Tyurina;V.A. Tyurin;N.V. Konduru.
Toxicology Letters (2006)

650 Citations

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