Andrew G. Bowie

Research.com Recognitions

• 2014 - Member of the Royal Irish Academy

Overview

Best Publications

• The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

  Luke A. J. O'Neill;Andrew G. Bowie

  3397
  Citations

• The History of Toll-like Receptors - Redefining Innate Immunity

  Luke A. J. O'Neill;Douglas Golenbock;Andrew G. Bowie

  2137
  Citations

• IFI16 is an innate immune sensor for intracellular DNA.

  Leonie Unterholzner;Sinead E. Keating;Marcin Baran;Kristy A. Horan

  1916
  Citations

• Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

  Katherine A. Fitzgerald;Eva M. Palsson-McDermott;Andrew G. Bowie;Andrew G. Bowie;Caroline A. Jefferies

  1679
  Citations

• Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

  Andrew Bowie;Luke A.J O’Neill

  1142
  Citations

• Viral evasion and subversion of pattern-recognition receptor signalling

  Andrew G. Bowie;Leonie Unterholzner

  887
  Citations

• Immune sensing of DNA

  Søren R. Paludan;Andrew G. Bowie

  859
  Citations

• The interleukin‐1 receptor/Toll‐like receptor superfamily: signal generators for pro‐inflammatory interleukins and microbial products

  Andrew Bowie;Luke A. J. O'Neill

  746
  Citations

• The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling

  Michael Carty;Rory Goodbody;Martina Schröder;Julianne Stack

  671
  Citations

• The Toll-IL-1 receptor adaptor family grows to five members

  Luke A.J. O'Neill;Katherine A Fitzgerald;Andrew G. Bowie

  638
  Citations

• A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling

  Andrew Bowie;Endre Kiss-Toth;Julian A. Symons;Geoffrey L. Smith

  621
  Citations

• The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

  Elizabeth C. Carroll;Lei Jin;Andres Mori;Natalia Muñoz-Wolf

  597
  Citations

• Structures of the HIN Domain:DNA Complexes Reveal Ligand Binding and Activation Mechanisms of the AIM2 Inflammasome and IFI16 Receptor.

  Tengchuan Jin;Andrew Perry;Jiansheng Jiang;Patrick Smith

  568
  Citations

• The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense.

  Mary T. Harte;Ismar R. Haga;Geraldine Maloney;Pearl Gray

  491
  Citations

• Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.

  Gillian Dunphy;Sinéad M Flannery;Jessica F Almine;Dympna J Connolly

  488
  Citations

• Vaccinia virus protein A46R targets multiple Toll-like–interleukin-1 receptor adaptors and contributes to virulence

  Julianne Stack;Ismar R. Haga;Martina Schröder;Nathan W. Bartlett

  468
  Citations

• Recognition of herpesviruses by the innate immune system

  Søren R. Paludan;Andrew G. Bowie;Kristy A. Horan;Katherine A. Fitzgerald

  446
  Citations

• Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKe-mediated IRF activation

  Martina Schröder;Marcin Baran;Andrew G Bowie

  443
  Citations

• Vitamin C inhibits NF-kappa B activation by TNF via the activation of p38 mitogen-activated protein kinase.

  Andrew Bowie;Luke Anthony John O'neill

  398
  Citations

• The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling.

  Sinead Flannery;Andrew G. Bowie

  379
  Citations