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Molecular Biology

D-Index
61
Citations
27583
World Ranking
1876
National Ranking
933

Overview

Richard W. Carthew is affiliated with Northwestern University in the United States. Their research primarily encompasses the field of Biochemistry, Genetics and Molecular Biology, with a concentration on molecular and cellular mechanisms.

Their work extends into several subfields, including:

  • Molecular Biology
  • Cell Biology
  • Cellular and Molecular Neuroscience
  • Geometry and Topology
  • Biophysics

Key topics explored in their research consist of:

  • Gene Regulatory Network Analysis
  • CRISPR and Genetic Engineering
  • Single-cell and spatial transcriptomics
  • Neurobiology and Insect Physiology Research
  • Hippo pathway signaling and YAP/TAZ
  • Advanced biosensing and bioanalysis techniques
  • Morphological variations and asymmetry

Recent publications authored or co-authored by Richard W. Carthew include:

  • "MicroRNA-mediated regulation of glucose and lipid metabolism," 2021, Nature Reviews Molecular Cell Biology
  • "Gene Regulation and Cellular Metabolism: An Essential Partnership," 2020, Trends in Genetics
  • "The effector mechanism of siRNA spherical nucleic acids," 2020, Proceedings of the National Academy of Sciences
  • "Global constraints within the developmental program of the Drosophila wing," 2021, eLife
  • "Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila," 2022, Cell Reports

The scientist maintains frequent collaborations with several researchers, including:

  • Madhav Mani
  • Vasyl Alba
  • James E. Carthew
  • Kevin G. Nyberg
  • Joseph Q. Nguyen

Publication venues where their work frequently appears include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Development
  • arXiv (Cornell University)
  • Nature Reviews Molecular Cell Biology

Best Publications

  • Origins and Mechanisms of miRNAs and siRNAs

    Richard W. Carthew;Erik J. Sontheimer

  • Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway

    Jason R Kennerdell;Richard W Carthew

  • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways.

    Young Sik Lee;Kenji Nakahara;John W Pham;Kevin Kim

  • An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

    Richard W. Carthew;Lewis A. Chodosh;Lewis A. Chodosh;Phillip A. Sharp

  • Human CCAAT-binding proteins have heterologous subunits

    Lewis A. Chodosh;Lewis A. Chodosh;Albert S. Baldwin;Richard W. Carthew;Phillip A. Sharp

  • RNA interference directs innate immunity against viruses in adult Drosophila.

    Xiao Hong Wang;Roghiyh Aliyari;Wan Xiang Li;Hong Wei Li

  • Stem cell division is regulated by the microRNA pathway.

    S. D. Hatfield;H. R. Shcherbata;K. A. Fischer;K. Nakahara

  • Heritable gene silencing in Drosophila using double-stranded RNA.

    Jason R. Kennerdell;Richard W. Carthew

  • A MicroRNA Imparts Robustness against Environmental Fluctuation during Development

    Xin Li;Justin J. Cassidy;Catherine A. Reinke;Stephen Fischboeck

  • Gene regulation by microRNAs.

    Richard W Carthew

  • A Dicer-2-Dependent 80S Complex Cleaves Targeted mRNAs during RNAi in Drosophila

    John W Pham;Janice L Pellino;Young Sik Lee;Richard W Carthew

  • A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor.

    L A Chodosh;R W Carthew;P A Sharp

  • Making a better RNAi vector for Drosophila: use of intron spacers.

    Young Sik Lee;Richard W. Carthew

  • Gene silencing by double-stranded RNA.

    Richard W Carthew

  • A microRNA Mediates EGF Receptor Signaling and Promotes Photoreceptor Differentiation in the Drosophila Eye

    Xin Li;Richard W. Carthew

  • Surface mechanics mediate pattern formation in the developing retina

    Takashi Hayashi;Takashi Hayashi;Richard W. Carthew

  • seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye.

    Richard W. Carthew;Gerald M. Rubin

  • Genome-wide survey of protein kinases required for cell cycle progression.

    M. Bettencourt-Dias;R. Giet;R. Giet;R. Sinka;A. Mazumdar

  • Silencing by small RNAs is linked to endosomal trafficking

    Young Sik Lee;Sigal Pressman;Arlise P. Andress;Kevin Kim

  • Silence from within: Endogenous siRNAs and miRNAs

    Erik J. Sontheimer;Richard W. Carthew

Frequent Co-Authors

Sascha Hilgenfeldt
Sascha Hilgenfeldt University of Illinois at Urbana-Champaign
Chung-I Wu
Chung-I Wu Sun Yat-sen University
Erik J. Sontheimer
Erik J. Sontheimer University of Massachusetts Chan Medical School
Gerald M. Rubin
Gerald M. Rubin Howard Hughes Medical Institute
Kevin P. White
Kevin P. White National University of Singapore
Aggelos K. Katsaggelos
Aggelos K. Katsaggelos Northwestern University
Johan A. Hellebust
Johan A. Hellebust University of Toronto
Hugo J. Bellen
Hugo J. Bellen Baylor College of Medicine
Chad A. Mirkin
Chad A. Mirkin Northwestern University

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