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Martin J.B. Taphoorn

Martin J.B. Taphoorn

Overview

Martin J.B. Taphoorn is affiliated with Leiden University in the Netherlands. Their research focus lies predominantly within the field of medicine, with significant contributions in genetics, pulmonary and respiratory medicine, radiology, nuclear medicine and imaging, pediatrics, perinatology and child health, as well as psychiatry and mental health.

Their main research topics include glioma diagnosis and treatment, pharmacological effects and toxicity studies, epilepsy research and treatment, cancer-related cognitive impairment studies, brain metastases and treatment, cancer survivorship and care, and meningioma and schwannoma management.

Taphoorn has contributed to several frequently cited papers, notably:

  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood, 2020, Nature Reviews Clinical Oncology
  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions, 2020, Neuro-Oncology
  • Systemic anticancer therapy-induced peripheral and central neurotoxicity: ESMO-EONS-EANO Clinical Practice Guidelines for diagnosis, prevention, treatment and follow-up, 2020, Annals of Oncology
  • International standards for the analysis of quality-of-life and patient-reported outcome endpoints in cancer randomised controlled trials: recommendations of the SISAQOL Consortium, 2020, The Lancet Oncology
  • Transcriptome analysis reveals tumor microenvironment changes in glioblastoma, 2023, Cancer Cell

Taphoorn has collaborated frequently with several researchers, including Linda Dirven, Johan A F Koekkoek, Martin J. van den Bent, Jaap C. Reijneveld, and Pim B. van der Meer.

Their work appears consistently in prominent publication venues such as Neuro-Oncology, Neuro-Oncology Practice, Journal of Neuro-Oncology, Neuro-Oncology Advances, and the European Journal of Cancer.

Best Publications

  • Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

    Roger Stupp;Warren P. Mason;Martin J. van den Bent;Michael Weller

  • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

    Roger Stupp;Monika E. Hegi;Warren P. Mason;Martin J. van den Bent

  • Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951

    Martin J. van den Bent;Alba A. Brandes;Martin J.B. Taphoorn;Johan M. Kros

  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.

    Michael Weller;Martin van den Bent;Matthias Preusser;Emilie Le Rhun

  • Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

    Roger Stupp;Roger Stupp;Monika E Hegi;Thierry Gorlia;Sara C Erridge

  • Adjuvant Procarbazine, Lomustine, and Vincristine Improves Progression-Free Survival but Not Overall Survival in Newly Diagnosed Anaplastic Oligodendrogliomas and Oligoastrocytomas: A Randomized European Organisation for Research and Treatment of Cancer Phase III Trial

    Martin J. van den Bent;Antoine F. Carpentier;Alba A. Brandes;Marc Sanson

  • European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

    Michael Weller;Martin van den Bent;Jörg C Tonn;Roger Stupp

  • Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial.

    Walter Taal;Hendrika M Oosterkamp;Annemiek M E Walenkamp;Hendrikus J Dubbink

  • Lomustine and Bevacizumab in Progressive Glioblastoma

    Wolfgang Wick;Thierry Gorlia;Martin Bendszus;Martin Taphoorn

  • Cognitive deficits in adult patients with brain tumours.

    Martin J.B. Taphoorn;Martin Klein

  • Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up

    Linda Douw;Martin Klein;Selene S. A. A. Fagel;Josje van den Heuvel

  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

    Patrick Y. Wen;Michael Weller;Eudocia Quant Lee;Brian M. Alexander

  • Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034

    Martin J. van den Bent;Alba A. Brandes;Roy Rampling;Mathilde C.M. Kouwenhoven

  • Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas

    M. J. van den Bent;J. S. Wefel;D. Schiff;M. J. B. Taphoorn

  • Epilepsy in low-grade gliomas: the impact on cognitive function and quality of life.

    Martin Klein;Nadine H J Engelberts;Henk M van der Ploeg;Dorotheé G A Kasteleijn-Nolst Trenité

  • Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

    Brigitta G Baumert;Brigitta G Baumert;Monika E Hegi;Martin J van den Bent;Andreas von Deimling

  • High-Dose Methotrexate-Based Chemotherapy Followed by Consolidating Radiotherapy in Non–AIDS-Related Primary Central Nervous System Lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial 20962

    Philip M.P. Poortmans;Hanneke C. Kluin-Nelemans;Hanny Haaxma-Reiche;Mars Van’t Veer

  • Phase II Study of First-Line Chemotherapy With Temozolomide in Recurrent Oligodendroglial Tumors: The European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971

    M J van den Bent;M J B Taphoorn;A A Brandes;Johan Menten

  • Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology

    Khê Hoang-Xuan;Eric Bessell;Jacoline Bromberg;Andreas F Hottinger

  • IDH1 and IDH2 Mutations Are Prognostic but not Predictive for Outcome in Anaplastic Oligodendroglial Tumors: A Report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

    Martin J. van den Bent;Hendrikus J. Dubbink;Yannick Marie;Alba A. Brandes

Frequent Co-Authors

Martin Klein
Martin Klein Vrije Universiteit Amsterdam
Andrew Bottomley
Andrew Bottomley European Organisation for Research and Treatment of Cancer
Martin J. van den Bent
Martin J. van den Bent Erasmus University Rotterdam
Roger Stupp
Roger Stupp Northwestern University
Neil K. Aaronson
Neil K. Aaronson Antoni van Leeuwenhoek Hospital
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Luc Deliens
Luc Deliens Vrije Universiteit Brussel
Alba A. Brandes
Alba A. Brandes Institute of Neurological Sciences
Michael Weller
Michael Weller University of Zurich
Madeleine King
Madeleine King University of Sydney

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