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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
16215
World Ranking
15936
National Ranking
6618

Overview

Wolfram Goessling is affiliated with Brigham and Women's Hospital in the United States. Their research spans multiple fields with a primary focus on medicine and biochemistry, genetics, and molecular biology. Their work incorporates subfields such as surgery, epidemiology, cell biology, molecular biology, and hepatology.

Their main research topics include:

  • Liver Disease Diagnosis and Treatment
  • Zebrafish Biomedical Research Applications
  • Liver physiology and pathology
  • Hippo pathway signaling and YAP/TAZ
  • Pancreatic function and diabetes
  • Birth, Development, and Health
  • Organ Transplantation Techniques and Outcomes

Goessling's recent papers demonstrate a focus on developmental biology, liver injury, and hematopoietic stem cell formation. Notable publications include:

  • "YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow," 2020, Developmental Cell
  • "Functional compensation precedes recovery of tissue mass following acute liver injury," 2020, Nature Communications
  • "Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production," 2020, Developmental Cell
  • "Hepatic Nervous System in Development, Regeneration, and Disease," 2021, Hepatology
  • "Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy," 2021, Journal of Cell Science

Frequent co-authors in their work include:

  • Marc S. Sherman
  • Trista E. North
  • Paul J. Wrighton
  • Isaac M. Oderberg
  • George Q. Daley

Their publications are often found in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Gastroenterology
  • Developmental Cell
  • Experimental Hematology
  • Hepatology

Best Publications

  • Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis

    Richard Mark White;Anna Sessa;Christopher Burke;Teresa Bowman

  • Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

    Trista E. North;Wolfram Goessling;Wolfram Goessling;Carl R. Walkley;Claudia Lengerke

  • The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML

    Yingzi Wang;Andrei Krivtsov;Amit U. Sinha;Trista Elizabeth North;Trista Elizabeth North

  • β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

    Joseph Rosenbluh;Deepak Nijhawan;Deepak Nijhawan;Deepak Nijhawan;Andrew G. Cox;Andrew G. Cox;Xingnan Li

  • Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration.

    Wolfram Goessling;Trista E. North;Trista E. North;Sabine Loewer;Sabine Loewer;Allegra M. Lord;Allegra M. Lord

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Hematopoietic Stem Cell Development Is Dependent on Blood Flow

    Trista E. North;Wolfram Goessling;Marian Peeters;Pulin Li

  • Hypoxia as a therapy for mitochondrial disease

    Isha H. Jain;Luca Zazzeron;Rahul Goli;Rahul Goli;Kristen Alexa

  • Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.

    Joseph D Mancias;Joseph D Mancias;Laura Pontano Vaites;Sahar Nissim;Sahar Nissim;Douglas E Biancur

  • Aminotransferase Levels and 20-Year Risk of Metabolic Syndrome, Diabetes, and Cardiovascular Disease

    Wolfram Goessling;Wolfram Goessling;Joseph M. Massaro;Ramachandran S. Vasan;Ramachandran S. Vasan;Ralph B. D'Agostino

  • Mitochondrial dysfunction remodels one-carbon metabolism in human cells

    Xiaoyan Robert Bao;Xiaoyan Robert Bao;Xiaoyan Robert Bao;Shao En Ong;Olga Goldberger;Jun Peng;Jun Peng

  • Merkel Cell Carcinoma

    Wolfram Goessling;Phillip H. McKee;Robert J. Mayer

  • Effects of RAS on the genesis of embryonal rhabdomyosarcoma.

    David M. Langenau;Matthew D. Keefe;Narie Y. Storer;Jeffrey R. Guyon

  • Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation.

    Corey Cutler;Pratik Multani;David Robbins;Haesook T. Kim

  • Prostaglandin E2 Enhances Human Cord Blood Stem Cell Xenotransplants and Shows Long-Term Safety in Preclinical Nonhuman Primate Transplant Models

    Wolfram Goessling;Robyn S. Allen;Xiao Guan;Ping Jin

  • Identification of small molecules for human hepatocyte expansion and iPS differentiation

    Jing Shan;Robert E Schwartz;Robert E Schwartz;Nathan T Ross;David J Logan

  • Zebrafish: An Important Tool for Liver Disease Research

    Wolfram Goessling;Kirsten C. Sadler

  • Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

    John C. Chambers;Weihua Zhang;Joban Sehmi;Xinzhong Li

  • Erratum: β-catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis (Cell (2012) 151 (1457-1473))

    Joseph Rosenbluh;Deepak Nijhawan;Andrew G. Cox;Xingnan Li

  • Author response: Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

    Joseph D Mancias;Joseph D Mancias;Laura Pontano Vaites;Sahar Nissim;Sahar Nissim;Douglas E Biancur

Frequent Co-Authors

Trista E. North
Trista E. North Boston Children's Hospital
Leonard I. Zon
Leonard I. Zon Harvard University
Caroline S. Fox
Caroline S. Fox MSD (United States)
George Q. Daley
George Q. Daley Boston Children's Hospital
Ignaty Leshchiner
Ignaty Leshchiner Broad Institute
Anna Köttgen
Anna Köttgen University of Freiburg
J. Wade Harper
J. Wade Harper Harvard Medical School
Vamsi K. Mootha
Vamsi K. Mootha Harvard Medical School
Tamara B. Harris
Tamara B. Harris National Institutes of Health
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam

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