Ralph T. Schwarz

Overview

Best Publications

• Activation of TLR2 and TLR4 by Glycosylphosphatidylinositols Derived from Toxoplasma gondii

  Françoise Debierre-Grockiego;Marco A. Campos;Nahid Azzouz;Jörg Schmidt

  380
  Citations

• Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites.

  Anthony A. Holder;Michael J. Lockyer;Karel G. Odink;Jasbir S. Sandhu

  370
  Citations

• Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway.

  S D Tachado;P Gerold;M J McConville;T Baldwin

  323
  Citations

• Glycosylphosphatidylinositol toxin of Plasmodium up-regulates intercellular adhesion molecule-1, vascular cell adhesion molecule-1, and E-selectin expression in vascular endothelial cells and increases leukocyte and parasite cytoadherence via tyrosine kinase-dependent signal transduction.

  L Schofield;S Novakovic;P Gerold;R T Schwarz

  321
  Citations

• Signal transduction in macrophages by glycosylphosphatidylinositols of Plasmodium, Trypanosoma, and Leishmania: activation of protein tyrosine kinases and protein kinase C by inositolglycan and diacylglycerol moieties.

  Souvenir D. Tachado;Peter Gerold;Ralph Schwarz;Suzanna Novakovic

  284
  Citations

• Structural analysis of the glycosyl-phosphatidylinositol membrane anchor of the merozoite surface proteins-1 and -2 of Plasmodium falciparum.

  Peter Gerold;Louis Schofield;Michael J. Blackman;Anthony A. Holder

  259
  Citations

• Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

  Kisaburo Nagamune;Tomoyoshi Nozaki;Yusuke Maeda;Kazuhito Ohishi

  245
  Citations

• Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti

  Emmanuel Cornillot;Kamel Hadj-Kaddour;Amina Dassouli;Benjamin Noel

  226
  Citations

• Glycosylphosphatidylinositols synthesized by asexual erythrocytic stages of the malarial parasite, Plasmodium falciparum. Candidates for plasmodial glycosylphosphatidylinositol membrane anchor precursors and pathogenicity factors.

  P Gerold;A Dieckmann-Schuppert;R T Schwarz

  210
  Citations

• Cell-free synthesis of glycosyl-phosphatidylinositol precursors for the glycolipid membrane anchor of Trypanosoma brucei variant surface glycoproteins. Structural characterization of putative biosynthetic intermediates.

  A. K. Menon;R. T. Schwarz;S. Mayor;G. A. M. Cross

  207
  Citations

• Apparent lack of N-glycosylation in the asexual intraerythrocytic stage of Plasmodium falciparum.

  Angela Dieckmann-Schuppert;Stephanie Bender;Maria Odenthal-Schnittler;Ernst Bause

  170
  Citations

• 1-deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes.

  V Gross;T Andus;T A Tran-Thi;R T Schwarz

  163
  Citations

• Evidence for glycosyl-phosphatidylinositol anchoring of Toxoplasma gondii major surface antigens.

  S Tomavo;R T Schwarz;J F Dubremetz

  153
  Citations

• Roles of Glycosylphosphatidylinositols of Toxoplasma gondii INDUCTION OF TUMOR NECROSIS FACTOR-α PRODUCTION IN MACROPHAGES

  Françoise Debierre-Grockiego;Nahid Azzouz;Jörg Schmidt;Jean-François Dubremetz

  138
  Citations

• Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

  Christine Sütterlin;Anton Horvath;Peter Gerold;Ralph T. Schwarz

  135
  Citations

• Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis

  C Sütterlin;M V Escribano;P Gerold;Y Maeda

  121
  Citations

• Inhibition of formation of complex oligosaccharides by the glucosidase inhibitor bromoconduritol

  R Datema;P A Romero;G Legler;R T Schwarz

  116
  Citations

• The protozoan inositol phosphorylceramide synthase: a novel drug target that defines a new class of sphingolipid synthase.

  Paul W. Denny;Hosam Shams-Eldin;Helen. P. Price;Deborah F. Smith

  114
  Citations

• Molecular structure of the “low molecular weight antigen” of Toxoplasma gondii: a glucose α1-4 N-acetylgalactosamine makes free glycosyl-phosphatidylinositols highly immunogenic

  Boris Striepen;Christina F Zinecker;Jan B.L Damm;Pedro A.T Melgers

  113
  Citations

• Strain variation in the circumsporozoite protein gene of Plasmodium falciparum.

  Michael J. Lockyer;Ralph T. Schwarz

  110
  Citations