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D. Channe Gowda

D. Channe Gowda

D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
10433
World Ranking
13963
National Ranking
67

Overview

D. Channe Gowda is affiliated with the University of Mysore in India and has a focused research portfolio primarily in the fields of Medicine and Immunology and Microbiology. Their work spans several subfields including Public Health, Environmental and Occupational Health, Immunology, Molecular Biology, Epidemiology, and Neurology, reflecting a broad approach to biomedical research.

The scientist's research extensively covers topics such as Malaria Research and Control, Mosquito-borne diseases and control, the Complement system in diseases, Trypanosoma species research and implications, Glycosylation and Glycoproteins Research, interferon and immune responses, and Ubiquitin and proteasome pathways.

Their publication record includes articles in well-known scientific journals. Recent papers authored or co-authored by D. Channe Gowda include:

  • The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation, 2020, Proceedings of the National Academy of Sciences
  • IL-4 Treatment Mitigates Experimental Cerebral Malaria by Reducing Parasitemia, Dampening Inflammation, and Lessening the Cytotoxicity of T Cells, 2020, The Journal of Immunology
  • Molecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding, 2020, Journal of Biological Chemistry
  • IL-4Rα signaling by CD8α+ dendritic cells contributes to cerebral malaria by enhancing inflammatory, Th1, and cytotoxic CD8+ T cell responses, 2021, Journal of Biological Chemistry
  • Glycosylation in malaria parasites: what do we know?, 2024, Trends in Parasitology

The venues publishing their work include:

  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • Trends in Parasitology
  • The Journal of Immunology
  • Tropical Parasitology

D. Channe Gowda frequently collaborates with other researchers in the field. Common co-authors include:

  • Kiran K. Dayanand
  • Kishore Punnath
  • Maria C. Bewley
  • L. Gautam
  • Xianzhu Wu

The body of work reflects a multidisciplinary approach addressing critical aspects of infectious disease biology, immunological responses, and molecular mechanisms. Their studies particularly emphasize malaria pathogenesis, immune regulation, and molecular interactions related to parasite biology.

Best Publications

  • Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols of Plasmodium falciparum CELL SIGNALING RECEPTORS, GLYCOSYLPHOSPHATIDYLINOSITOL (GPI) STRUCTURAL REQUIREMENT, AND REGULATION OF GPI ACTIVITY

    Gowdahalli Krishnegowda;Adeline M. Hajjar;Jianzhong Zhu;Erika J. Douglass

  • Glycosylphosphatidylinositol anchors of Plasmodium falciparum: molecular characterization and naturally elicited antibody response that may provide immunity to malaria pathogenesis.

    Ramachandra S. Naik;Ora Lee H. Branch;Amina S. Woods;Matam Vijaykumar

  • Characterization of proteoglycans of human placenta and identification of unique chondroitin sulfate proteoglycans of the intervillous spaces that mediate the adherence of Plasmodium falciparum-infected erythrocytes to the placenta.

    Rajeshwara N. Achur;Manojkumar Valiyaveettil;Abdulnaser Alkhalil;Christian F. Ockenhouse

  • Induction of Proinflammatory Responses in Macrophages by the Glycosylphosphatidylinositols of Plasmodium falciparum THE REQUIREMENT OF EXTRACELLULAR SIGNAL-REGULATED KINASE, p38, c-Jun N-TERMINAL KINASE AND NF-κB PATHWAYS FOR THE EXPRESSION OF PROINFLAMMATORY CYTOKINES AND NITRIC OXIDE

    Jianzhong Zhu;Gowdahalli Krishnegowda;D. Channe Gowda

  • Gravidity-dependent production of antibodies that inhibit binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate proteoglycan during pregnancy.

    Iona O'Neil-Dunne;Iona O'Neil-Dunne;Rajeshwara N. Achur;Sean T. Agbor-Enoh;Sean T. Agbor-Enoh;Sean T. Agbor-Enoh;Manojkumar Valiyaveettil

  • TLR-mediated cell signaling by malaria GPIs.

    D. Channe Gowda

  • Glycosylphosphatidylinositol Anchors Represent the Major Carbohydrate Modification in Proteins of Intraerythrocytic Stage Plasmodium falciparum

    D. Channe Gowda;Priyadarshan Gupta;Eugene A. Davidson

  • Hemozoin Increases IFN-γ-Inducible Macrophage Nitric Oxide Generation Through Extracellular Signal-Regulated Kinase- and NF-κB-Dependent Pathways

    Maritza Jaramillo;D. Channe Gowda;Danuta Radzioch;Martin Olivier;Martin Olivier

  • Schiff's bases of quinazolinone derivatives: Synthesis and SAR studies of a novel series of potential anti-inflammatory and antioxidants.

    K.P. Rakesh;H.M. Manukumar;D. Channe Gowda

  • Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses

    Xianzhu Wu;Nagaraj M. Gowda;Sanjeev Kumar;D. Channe Gowda

  • CD36 and TLR Interactions in Inflammation and Phagocytosis: Implications for Malaria

    Laura K. Erdman;Gabriela Cosio;Andrew J. Helmers;D. Channe Gowda

  • Parasite Recognition and Signaling Mechanisms in Innate Immune Responses to Malaria.

    D. Channe Gowda;Xianzhu Wu

  • Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A.

    Kavita Singh;Apostolos G Gittis;Phuc Nguyen;D Channe Gowda

  • Structural requirements for the adherence of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate proteoglycans of human placenta.

    Abdulnaser Alkhalil;Rajeshwara N. Achur;Manojkumar Valiyaveettil;Christian F. Ockenhouse

  • C5 deficiency and C5a or C5aR blockade protects against cerebral malaria

    Samir N. Patel;Joanne Berghout;Fiona E. Lovegrove;Fiona E. Lovegrove;Kodjo Ayi;Kodjo Ayi

  • Presence of the HNK-1 epitope on poly(N-acetyllactosaminyl) oligosaccharides and identification of multiple core proteins in the chondroitin sulfate proteoglycans of brain.

    D. C. Gowda;R. U. Margolis;R. U. Margolis;R. K. Margolis;R. K. Margolis

  • Induction of nitric oxide synthase in Anopheles stephensi by Plasmodium falciparum: mechanism of signaling and the role of parasite glycosylphosphatidylinositols.

    Junghwa Lim;D. Channe Gowda;Gowdahalli Krishnegowda;Shirley Luckhart

  • Plasmodium falciparum Histones Induce Endothelial Proinflammatory Response and Barrier Dysfunction

    Mark R. Gillrie;Kristine Lee;D. Channe Gowda;Shevaun P. Davis

  • Structural studies of polysaccharides from aloe vera

    D. Channe Gowda;Belkavadi Neelisiddaiah;Yernool V. Anjaneyalu

  • Plasmodium falciparum-infected erythrocytes adhere both in the intervillous space and on the villous surface of human placenta by binding to the low-sulfated chondroitin sulfate proteoglycan receptor.

    Arivalagan Muthusamy;Rajeshwara N. Achur;Veer P. Bhavanandan;Genevieve G. Fouda

Frequent Co-Authors

Kanchugarakoppal S. Rangappa
Kanchugarakoppal S. Rangappa University of Mysore
Kevin C. Kain
Kevin C. Kain University Health Network
Christian F. Ockenhouse
Christian F. Ockenhouse Walter Reed Army Institute of Research
W. Conrad Liles
W. Conrad Liles University of Washington
Dan W. Urry
Dan W. Urry University of Alabama at Birmingham
Roland Schauer
Roland Schauer Kiel University
Liwang Cui
Liwang Cui University of South Florida
Siddaramaiah
Siddaramaiah University of Mysore
Nicholas M. Anstey
Nicholas M. Anstey Charles Darwin University
Satoshi Uematsu
Satoshi Uematsu Osaka Metropolitan University

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