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Genetics
Finland
2026
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Genetics and Molecular Biology
Finland
2024

D-Index & Metrics

Genetics

D-Index
98
Citations
30218
World Ranking
813
National Ranking
5

Medicine

D-Index
99
Citations
31168
World Ranking
8685
National Ranking
102

Research.com Recognitions

  • 2026 - Research.com Genetics in Finland Leader Award
  • 2025 - Research.com Genetics in Finland Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Finland Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Finland Leader Award
  • 2023 - Research.com Molecular Biology in Finland Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Finland Leader Award

Overview

Sakari Knuutila is affiliated with the University of Helsinki in Finland and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their work spans several interconnected fields, primarily focusing on molecular biology and oncology with applications in pulmonary and respiratory medicine, cancer research, and surgery.

Their research explores key topics including:

  • Gut microbiota and health
  • Pancreatic and hepatic oncology research
  • Epigenetics and DNA methylation
  • Cancer genomics and diagnostics
  • Genetic factors in colorectal cancer
  • Clostridium difficile and Clostridium perfringens research
  • Ginseng biological effects and applications

Knuutila has published in a range of scientific journals, with frequent appearances in:

  • Gut Pathogens
  • Anticancer Research
  • International Journal of Molecular Sciences
  • Biomolecules
  • Oncogene

Their publication record includes the following recent papers showcasing research linking microbiota and oncogenomic changes in gastrointestinal cancers:

  • Gut Microbiota and Host Gene Mutations in Colorectal Cancer Patients and Controls of Iranian and Finnish Origin, 2020, Anticancer Research
  • Gut microbiota of patients with different subtypes of gastric cancer and gastrointestinal stromal tumors, 2021, Gut Pathogens
  • Microbiota Alterations and Their Association with Oncogenomic Changes in Pancreatic Cancer Patients, 2021, International Journal of Molecular Sciences
  • Oncogenomic Changes in Pancreatic Cancer and Their Detection in Stool, 2022, Biomolecules
  • Fecal profiling reveals a common microbial signature for pancreatic cancer in Finnish and Iranian cohorts, 2025, Gut Pathogens

Knuutila collaborates frequently with several researchers, including:

  • Arto Kokkola
  • Pauli Puolakkainen
  • Virinder Kaur Sarhadi
  • Heidelinde Sammallahti
  • Reza Ghanbari

Their research integrates multidisciplinary approaches to uncover relationships between microbial communities, genetic mutations, and cancer progression, with particular emphasis on gastrointestinal and pancreatic oncology. The studies conducted by Knuutila and collaborators often involve comparative cohorts originating from different geographic and ethnic backgrounds, such as Finnish and Iranian populations, to better understand disease mechanisms across populations.

Best Publications

  • Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities.

    Gunnar Juliusson;David G. Oscier;Margaret Fitchett;Fiona M. Ross

  • DNA copy number amplifications in human neoplasms : Review of comparative genomic hybridization studies

    S. Knuutila;A.-M. Björkqvist;K. Autio;M. Tarkkanen

  • Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

    A Hemminki;I Tomlinson;D Markie;H Järvinen

  • DNA Copy Number Losses in Human Neoplasms

    Sakari Knuutila;Yan Aalto;Kirsi Autio;Anna Maria Björkqvist

  • A novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domains.

    J Partanen;E Armstrong;T P Mäkelä;J Korhonen

  • CDKN2A, NF2, and JUN are dysregulated among other genes by miRNAs in malignant mesothelioma -A miRNA microarray analysis.

    Mohamed Guled;Leo Lahti;Leo Lahti;Pamela M. Lindholm;Kaisa Salmenkivi

  • Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia.

    Peter J. Kourlas;Matthew P. Strout;Brian Becknell;Maria Luisa Veronese

  • RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability

    Katri Heikkinen;Katrin Rapakko;Sanna Maria Karppinen;Hannele Erkko

  • DNA sequence copy number changes in gastrointestinal stromal tumors: tumor progression and prognostic significance.

    Wa’el El-Rifai;Maarit Sarlomo-Rikala;Leif C. Andersson;Sakari Knuutila

  • Rearrangement of ALL1 (MLL) in Acute Myeloid Leukemia with Normal Cytogenetics

    Michael A. Caligiuri;Matthew P. Strout;David Lawrence;Diane C. Arthur

  • Concomitant loss of chromosome 3 and whole arm losses and gains of chromosome 1, 6, or 8 in metastasizing primary uveal melanoma.

    Yan Aalto;Lotta Eriksson;Stefan Seregard;Olle Larsson

  • BCL2 Overexpression Associated With Chromosomal Amplification in Diffuse Large B-Cell Lymphoma

    Outi Monni;Heikki Joensuu;Kaarle Franssila;Juha Klefstrom

  • Targets of Gene Amplification and Overexpression at 17q in Gastric Cancer

    Asta Varis;Maija Wolf;Maija Wolf;Outi Monni;Marja Leena Vakkari

  • Hepatocyte Growth Factor Receptor, Matrix Metalloproteinase-11, Tissue Inhibitor of Metalloproteinase-1, and Fibronectin Are Up-Regulated in Papillary Thyroid Carcinoma A cDNA and Tissue Microarray Study

    Veli-Matti Wasenius;Samuli Hemmer;Eeva Kettunen;Sakari Knuutila

  • Increased expression of high mobility group A proteins in lung cancer.

    VK Sarhadi;H Wikman;H Wikman;K Salmenkivi;E Kuosma

  • DNA copy number changes in diffuse large B-cell lymphoma--comparative genomic hybridization study.

    Outi Monni;Heikki Joensuu;Kaarle Franssila;Sakari Knuutila

  • Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array

    Harriet Wikman;Harriet Wikman;Eeva Kettunen;Jouni K Seppänen;Antti Karjalainen

  • Uniparental disomy in cancer.

    Musaffe Tuna;Sakari Knuutila;Gordon B. Mills

  • Partial Tandem Duplication of ALL1 as a Recurrent Molecular Defect in Acute Myeloid Leukemia with Trisomy 11

    Michael A. Caligiuri;Matthew P. Strout;Steven A. Schichman;Krzysztof Mrózek

  • Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization

    M Tarkkanen;R Karhu;A Kallioniemi;I Elomaa

Frequent Co-Authors

Marcelo L. Larramendy
Marcelo L. Larramendy National University of La Plata
Wael El-Rifai
Wael El-Rifai University of Miami
Tapani Ruutu
Tapani Ruutu University of Helsinki
Päivi Peltomäki
Päivi Peltomäki University of Helsinki
Outi Monni
Outi Monni University of Helsinki
Leif C. Andersson
Leif C. Andersson University of Helsinki
Piero Picci
Piero Picci University of Bologna
Heikki Joensuu
Heikki Joensuu University of Helsinki
Lauri A. Aaltonen
Lauri A. Aaltonen University of Helsinki
Juha Kere
Juha Kere Karolinska Institute

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Related Online Degrees & Career Pathways

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