What is he best known for?
The fields of study he is best known for:
- Gene
- Cancer
- Internal medicine
The scientist’s investigation covers issues in Comparative genomic hybridization, Molecular biology, Pathology, Genetics and Cancer research.
His study in Comparative genomic hybridization is interdisciplinary in nature, drawing from both Gene duplication and Carcinogenesis, Cancer.
His Molecular biology study integrates concerns from other disciplines, such as Human genome, Gene expression profiling, DNA, Lymphoma and Colorectal cancer.
His Pathology research includes themes of Stomach, Internal medicine, Karyotype and Cytogenetics.
Sakari Knuutila interconnects Messenger RNA, Gene expression and Gene isoform in the investigation of issues within Cancer research.
His studies in Gene integrate themes in fields like Lung cancer and Adenocarcinoma.
His most cited work include:
- Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. (548 citations)
- DNA copy number amplifications in human neoplasms : Review of comparative genomic hybridization studies (536 citations)
- Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis (428 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Molecular biology, Comparative genomic hybridization, Genetics, Pathology and Cancer research.
His Molecular biology study incorporates themes from Cell culture, Chromosomal translocation, Amplicon, Mitosis and Antibody.
Sakari Knuutila focuses mostly in the field of Comparative genomic hybridization, narrowing it down to topics relating to Cancer and, in certain cases, Oncology.
The various areas that Sakari Knuutila examines in his Pathology study include Leukemia, In situ hybridization and Cytogenetics.
His Cytogenetics research is multidisciplinary, relying on both Aneuploidy and Karyotype.
His research integrates issues of Carcinoma, Immunology, Bioinformatics and Gene expression profiling in his study of Cancer research.
He most often published in these fields:
- Molecular biology (34.46%)
- Comparative genomic hybridization (34.94%)
- Genetics (29.17%)
What were the highlights of his more recent work (between 2010-2021)?
- Cancer research (26.44%)
- microRNA (4.49%)
- Molecular biology (34.46%)
In recent papers he was focusing on the following fields of study:
Sakari Knuutila mainly investigates Cancer research, microRNA, Molecular biology, Pathology and Internal medicine.
His Cancer research study combines topics from a wide range of disciplines, such as Immunohistochemistry, Bioinformatics, KRAS, Carcinoma and Gene.
His studies deal with areas such as Gene expression profiling, Microarray analysis techniques, Myeloid leukemia, Regulation of gene expression and Bone marrow as well as microRNA.
His Molecular biology study combines topics in areas such as Comparative genomic hybridization, Real-time polymerase chain reaction and Copy-number variation.
His Comparative genomic hybridization study is concerned with the larger field of Genetics.
His studies examine the connections between Internal medicine and genetics, as well as such issues in Oncology, with regards to Targeted therapy, Young adult, Malignancy and Biomarker.
Between 2010 and 2021, his most popular works were:
- miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. (109 citations)
- Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer. (104 citations)
- Comparison of Targeted Next-Generation Sequencing (NGS) and Real-Time PCR in the Detection of EGFR, KRAS, and BRAF Mutations on Formalin-Fixed, Paraffin-Embedded Tumor Material of Non-Small Cell Lung Carcinoma-Superiority of NGS (103 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cancer
- Internal medicine
His main research concerns Cancer research, microRNA, Molecular biology, Cancer and Pathology.
The study incorporates disciplines such as Immunohistochemistry, Downregulation and upregulation, Gene and Merkel cell carcinoma, Merkel cell polyomavirus in addition to Cancer research.
His microRNA research is multidisciplinary, incorporating perspectives in Bioinformatics, Gene expression profiling, Microarray analysis techniques, Myeloid leukemia and Colorectal cancer.
His Molecular biology research is multidisciplinary, incorporating elements of Anaplastic lymphoma kinase, Comparative genomic hybridization, Fusion gene and Real-time polymerase chain reaction.
Sakari Knuutila combines subjects such as CDKN2A and DNA methylation with his study of Comparative genomic hybridization.
His research investigates the link between Cancer and topics such as Carcinoma that cross with problems in Chromosome 3, Fluorescence in situ hybridization and Adenocarcinoma.
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