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D-Index
73
Citations
26042
World Ranking
19554
National Ranking
9735

Overview

Richard F. Loeser is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily spans the field of Medicine, with a strong focus on Rheumatology, Surgery, Pharmacology, Molecular Biology, and Cancer Research as related subfields.

They have contributed to various topics within osteoarthritis and related conditions. Key areas of their work include:

  • Osteoarthritis Treatment and Mechanisms
  • Inflammatory mediators and NSAID effects
  • Total Knee Arthroplasty Outcomes
  • Knee injuries and reconstruction techniques
  • Rheumatoid Arthritis Research and Therapies
  • Cancer-related molecular mechanisms research
  • Cytokine Signaling Pathways and Interactions

Richard F. Loeser has published research articles in several notable venues. The most frequent publication outlets are:

  • Osteoarthritis and Cartilage
  • UNC Libraries
  • Arthritis & Rheumatology
  • Osteoarthritis and Cartilage Open
  • bioRxiv (Cold Spring Harbor Laboratory)

Among their recent scholarly papers are the following:

  • "Diagnosis and Treatment of Hip and Knee Osteoarthritis," 2021, published in JAMA
  • "Mechanisms and therapeutic implications of cellular senescence in osteoarthritis," 2020, published in Nature Reviews Rheumatology
  • "Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee Osteoarthritis," 2021, published in JAMA
  • "Effect of Diet and Exercise on Knee Pain in Patients With Osteoarthritis and Overweight or Obesity," 2022, published in JAMA
  • "Association of Increased Serum Lipopolysaccharide, But Not Microbial Dysbiosis, With Obesity-Related Osteoarthritis," 2021, published in Arthritis & Rheumatology

Collaboration is an important aspect of their research activities. Frequent co-authors include:

  • Brian O. Diekman
  • Stephen P. Messier
  • Liubov Arbeeva
  • Amanda E. Nelson
  • Philip Coryell

Best Publications

  • Osteoarthritis: A Disease of the Joint as an Organ

    Richard Frank Loeser;Steven R. Goldring;Carla R. Scanzello;Mary B. Goldring

  • Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial.

    Stephen P. Messier;Richard F. Loeser;Gary D. Miller;Timothy M. Morgan

  • Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review.

    Jeffrey N. Katz;Jeffrey N. Katz;Kaetlyn R. Arant;Richard F. Loeser

  • Ageing and the pathogenesis of osteoarthritis

    Richard F. Loeser;John A. Collins;Brian O. Diekman

  • Effects of Intensive Diet and Exercise on Knee Joint Loads, Inflammation, and Clinical Outcomes Among Overweight and Obese Adults With Knee Osteoarthritis: The IDEA Randomized Clinical Trial

    Stephen P. Messier;Shannon L. Mihalko;Claudine Legault;Gary D. Miller

  • Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix

    Richard F. Loeser

  • Why is osteoarthritis an age-related disease?

    A. Shane Anderson;Richard F. Loeser

  • Aging-related inflammation in osteoarthritis.

    Meredith A. Greene;Richard F. Loeser

  • Age-related changes in the musculoskeletal system and the development of osteoarthritis.

    Richard F. Loeser

  • Reactive oxygen species, aging and articular cartilage homeostasis.

    Jesalyn A. Bolduc;John A. Collins;Richard Frank Loeser

  • Osteoarthritis of the knee: effects on gait, strength, and flexibility

    Stephen P. Messier;Richard F. Loeser;Jacqueline L. Hoover;Elliott L. Semble

  • Effects of aging on articular cartilage homeostasis

    Martin Lotz;Richard F. Loeser

  • Exercise and weight loss in obese older adults with knee osteoarthritis: a preliminary study.

    Stephen P. Messier;Richard F. Loeser;Michelle N. Mitchell;Gianfranco Valle

  • Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide.

    Richard F. Loeser

  • Aging and osteoarthritis.

    Richard F. Loeser

  • Intensive Weight Loss Program Improves Physical Function in Older Obese Adults with Knee Osteoarthritis

    Gary D. Miller;Barbara J. Nicklas;Cralen Davis;Richard F. Loeser

  • Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products.

    Raghunatha R. Yammani;Cathy S. Carlson;Anne R. Bresnick;Richard F. Loeser

  • Osteoarthritis in cynomolgus macaques. III: Effects of age, gender, and subchondral bone thickness on the severity of disease.

    Cathy S. Carlson;Richard F. Loeser;Connie B. Purser;Jean F. Gardin

  • Integrins and chondrocyte-matrix interactions in articular cartilage.

    Richard F. Loeser

  • Integrin-mediated attachment of articular chondrocytes to extracellular matrix proteins.

    Richard F. Loeser

Frequent Co-Authors

Barbara J. Nicklas
Barbara J. Nicklas Wake Forest University
David J. Hunter
David J. Hunter Harvard University
Cathy S. Carlson
Cathy S. Carlson University of Minnesota
Ali Guermazi
Ali Guermazi Boston University
Felix Eckstein
Felix Eckstein Paracelsus Medical University
Leslie B. Poole
Leslie B. Poole Wake Forest University
Sarah L. Booth
Sarah L. Booth Tufts University
Jeff D. Williamson
Jeff D. Williamson Wake Forest University
J. Jeffrey Carr
J. Jeffrey Carr Vanderbilt University Medical Center
Leigh F. Callahan
Leigh F. Callahan University of North Carolina at Chapel Hill

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