World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
12776
World Ranking
12508
National Ranking
5354

Overview

Hee-Jeong Im is a researcher affiliated with the University of Illinois at Chicago in the United States. Their work primarily focuses on medicine and the intersecting fields of biochemistry, genetics, and molecular biology. They have contributed extensively to the study of osteoarthritis, inflammation, pain mechanisms, and related molecular processes.

The main areas of research include:

  • Osteoarthritis Treatment and Mechanisms
  • Inflammatory mediators and NSAID effects
  • Pain Mechanisms and Treatments
  • Angiogenesis and VEGF in Cancer
  • Antimicrobial Peptides and Activities
  • Periodontal Regeneration and Treatments
  • Spondyloarthritis Studies and Treatments

Their work spans several subfields of study such as rheumatology, pharmacology, molecular biology, physiology, and cellular and molecular neuroscience. These interdisciplinary approaches facilitate deeper investigation into disease mechanisms and potential therapeutic strategies.

Im has published research articles in prominent scientific journals. Some of the recent papers include:

  • "Nanoparticle-based inhibition of vascular endothelial growth factor receptors alleviates osteoarthritis pain and cartilage damage," 2024, Science Advances
  • "Targeting Vascular Endothelial Growth Factor Receptors as a Therapeutic Strategy for Osteoarthritis and Associated Pain," 2023, International Journal of Biological Sciences
  • "Lactobacillus acidophilus Mitigates Osteoarthritis-Associated Pain, Cartilage Disintegration and Gut Microbiota Dysbiosis in an Experimental Murine OA Model," 2022, Biomedicines
  • "Gut-microbiota modulation: The impact of the gut-microbiota on osteoarthritis," 2021, Gene
  • "Sensory Neuron-Specific Deletion of Tropomyosin Receptor Kinase A (TrkA) in Mice Abolishes Osteoarthritis (OA) Pain via NGF/TrkA Intervention of Peripheral Sensitization," 2022, International Journal of Molecular Sciences

Frequent coauthors in these studies include André J. van Wijnen, InSug O-Sullivan, Kaige Ma, Benjamin Bruce, and Fackson Mwale. This collaborative work reflects a multidisciplinary team approach in tackling complex biomedical challenges.

Im's research is often published in journals where they have multiple contributions, such as Gene, Biomedicines, Biomolecules, Science Advances, and the International Journal of Biological Sciences. This highlights a consistent engagement with platforms specializing in genetic, molecular, and medical research.

Best Publications

  • Osteoarthritis: toward a comprehensive understanding of pathological mechanism.

    Di Chen;Jie Shen;Weiwei Zhao;Tingyu Wang

  • A current review of molecular mechanisms regarding osteoarthritis and pain

    Andrew S. Lee;Michael B. Ellman;Dongyao Yan;Jeffrey S. Kroin

  • MMP13 is a critical target gene during the progression of osteoarthritis

    Meina Wang;Meina Wang;Erik R Sampson;Hongting Jin;Hongting Jin;Jia Li;Jia Li

  • Repetitive mechanical stretching modulates IL-1β induced COX-2, MMP-1 expression, and PGE2 production in human patellar tendon fibroblasts

    Guoguang Yang;Hee-Jeong Im;James H.-C. Wang

  • Mechanoregulation of gene expression in fibroblasts.

    James H.-C. Wang;Bhavani P. Thampatty;Jeen-Shang Lin;Hee-Jeong Im

  • Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis

    Richard F. Loeser;Raghunatha R. Yammani;Cathy S. Carlson;Hong Chen

  • The Bone-specific Expression of Runx2 Oscillates during the Cell Cycle to Support a G1-related Antiproliferative Function in Osteoblasts

    Mario Galindo;Jitesh Pratap;Daniel W. Young;Hayk Hovhannisyan

  • MicroRNA-146a is Linked to Pain-related Pathophysiology of Osteoarthritis

    Xin Li;Gary Gibson;Jae Sung Kim;Jeffrey Kroin

  • NF-κB Mediates the Stimulation of Cytokine and Chemokine Expression by Human Articular Chondrocytes in Response to Fibronectin Fragments

    Judit I. Pulai;Hong Chen;Hee Jeong Im;Sanjay Kumar

  • Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis

    Meina Wang;Jie Shen;Hongting Jin;Hongting Jin;Hee Jeong Im

  • HGF Mediates the Anti-inflammatory Effects of PRP on Injured Tendons

    Jianying Zhang;Kellie K. Middleton;Freddie H. Fu;Hee-Jeong Im

  • MicroRNA functions in osteogenesis and dysfunctions in osteoporosis.

    Andre J. Van Wijnen;Jeroen Van De Peppel;Johannes P. Van Leeuwen;Jane B. Lian

  • Basic Fibroblast Growth Factor Stimulates Matrix Metalloproteinase-13 via the Molecular Cross-talk between the Mitogen-activated Protein Kinases and Protein Kinase Cδ Pathways in Human Adult Articular Chondrocytes

    Hee Jeong Im;Prasuna Muddasani;Viswanathan Natarajan;Thomas M. Schmid

  • Fibroblast growth factor control of cartilage homeostasis

    M.B. Ellman;D. Yan;K. Ahmadinia;D. Chen

  • Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model.

    Hee Jeong Im;Jae Sung Kim;Xin Li;Naomi Kotwal

  • Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain

    John L Hamilton;Masashi Nagao;Brett R Levine;Di Chen

  • Biological impact of the fibroblast growth factor family on articular cartilage and intervertebral disc homeostasis.

    Michael B. Ellman;Howard S. An;Prasuna Muddasani;Hee-Jeong Im

  • Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis

    Xin Li;Michael Ellman;Prasuna Muddasani;James H.C. Wang

  • Inhibitory Effects of Insulin-like Growth Factor-1 and Osteogenic Protein-1 on Fibronectin Fragment- and Interleukin-1β-stimulated Matrix Metalloproteinase-13 Expression in Human Chondrocytes

    Hee Jeong Im;Carol Pacione;Susan Chubinskaya;Andre J. Van Wijnen

  • Articular Chondrocytes Express the Receptor for Advanced Glycation End Products

    Richard F. Loeser;Raghunatha R. Yammani;Cathy S. Carlson;Hong Chen

Frequent Co-Authors

Di Chen
Di Chen Chinese Academy of Sciences
Howard S. An
Howard S. An Rush University Medical Center
Guozhi Xiao
Guozhi Xiao Southern University of Science and Technology
Andre J. Van Wijnen
Andre J. Van Wijnen University of Connecticut Health Center
Gary S. Stein
Gary S. Stein University of Vermont
Jie Fan
Jie Fan University of Pittsburgh
Ali Keshavarzian
Ali Keshavarzian Rush University Medical Center
Simon M. Cool
Simon M. Cool University of Queensland
Marcel Karperien
Marcel Karperien University of Twente
Rajiv Kumar
Rajiv Kumar Mayo Clinic

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Hee-Jeong Im

Trending Scientists