World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
28542
World Ranking
15336
National Ranking
6396

Overview

Jie Fan is affiliated with the University of Pittsburgh in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, and medicine, with a notable concentration on molecular biology and immunology within the subfields of pulmonary and respiratory medicine and cancer research.

The scientist's recent publications cover various topics related to immune response, inflammation, and cellular mechanisms in disease contexts such as sepsis and organ injury. Key recent papers include:

  • "Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock" (2020, Critical Care)
  • "Exosomal mediators in sepsis and inflammatory organ injury: unraveling the role of exosomes in intercellular crosstalk and organ dysfunction" (2024, Military Medical Research)
  • "Mechanism of lactic acidemia-promoted pulmonary endothelial cells death in sepsis: role for CIRP-ZBP1-PANoptosis pathway" (2024, Military Medical Research)
  • "Neutrophil in Reverse Migration: Role in Sepsis" (2021, Frontiers in Immunology)
  • "Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated Pyroptosis" (2021, Cellular and Molecular Gastroenterology and Hepatology)

Jie Fan has collaborated frequently with several researchers, including Timothy R. Billiar, Melanie J. Scott, Yuehua Li, Patricia Loughran, and Mark A. Wilson.

Their research has appeared in a range of venues, with multiple publications in:

  • Experimental Eye Research
  • Military Medical Research
  • Communications Biology
  • Frontiers in Immunology
  • SSRN Electronic Journal

The scientist's work extends into research topics such as immune response and inflammation, neutrophil, myeloperoxidase and oxidative mechanisms, S100 proteins and annexins, protein degradation and inhibitors, animal disease management and epidemiology, RNA modifications and cancer, and sphingolipid metabolism and signaling.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Hemorrhagic Shock Induces NAD(P)H Oxidase Activation in Neutrophils: Role of HMGB1-TLR4 Signaling

    Jie Fan;Jie Fan;Yuehua Li;Ryan M. Levy;Janet J. Fan

  • Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors.

    Jie Fan;Asrar B. Malik

  • TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase

    Jie Fan;Randall S. Frey;Asrar B. Malik

  • Programmed cell death and its role in inflammation

    Yong Yang;Gening Jiang;Peng Zhang;Jie Fan

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Macrophage endocytosis of high-mobility group box 1 triggers pyroptosis

    J Xu;Y Jiang;J Wang;X Shi

  • Regulation of alveolar macrophage death in acute lung inflammation.

    Erica K Y Fan;Jie Fan;Jie Fan

  • Heatstroke induces liver injury via IL-1β and HMGB1-induced pyroptosis

    Yan Geng;Qiang Ma;Ya-Nan Liu;Na Peng

  • miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression

    Jiang Li;Mohammed Ghazwani;Yifei Zhang;Jianqin Lu

  • An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy

    Yichao Chen;Rui Xia;Yixian Huang;Wenchen Zhao

  • Inflammasome and autophagy regulation - a two-way street.

    Qian Sun;Jie Fan;Jie Fan;Timothy R. Billiar;Melanie J. Scott

  • Hemorrhagic Shock Activation of NLRP3 Inflammasome in Lung Endothelial Cells

    Meng Xiang;Xiaolian Shi;Xiaolian Shi;Yuehua Li;Yuehua Li;Jia Xu;Jia Xu

  • Role of Neutrophil NADPH Oxidase in the Mechanism of Tumor Necrosis Factor-α-induced NF-κB Activation and Intercellular Adhesion Molecule-1 Expression in Endothelial Cells

    Jie Fan;Randall S. Frey;Arshad Rahman;Asrar B. Malik

  • Neutrophil extracellular traps promote macrophage pyroptosis in sepsis

    Linsong Chen;Yanfeng Zhao;Dengming Lai;Peng Zhang

  • Regulation of Toll-Like Receptor 4 Expression in the Lung Following Hemorrhagic Shock and Lipopolysaccharide

    Jie Fan;Andras Kapus;Philip A. Marsden;Yue Hua Li

  • Location is the key to function: HMGB1 in sepsis and trauma-induced inflammation.

    Meihong Deng;Melanie J. Scott;Jie Fan;Jie Fan;Timothy R. Billiar

  • LPS activation of Toll-like receptor 4 signals CD11b/CD18 expression in neutrophils.

    Ximing Zhou;Xiao Pei Gao;Jie Fan;Qinghui Liu

Frequent Co-Authors

Timothy R. Billiar
Timothy R. Billiar University of Pittsburgh
Guozhi Xiao
Guozhi Xiao Southern University of Science and Technology
Wen Xie
Wen Xie University of Pittsburgh
Song Li
Song Li University of Pittsburgh
Yoram Vodovotz
Yoram Vodovotz University of Pittsburgh
Sergio Lavandero
Sergio Lavandero University of Chile
Evelina Gatti
Evelina Gatti Aix-Marseille University
Boris Zhivotovsky
Boris Zhivotovsky Karolinska Institute
Ping Wang
Ping Wang Feinstein Institute for Medical Research
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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