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Biology and Biochemistry

D-Index
59
Citations
17606
World Ranking
12323
National Ranking
33

Overview

Mark B. Hampton is affiliated with the University of Otago in New Zealand. Their research spans multiple fields within the broader areas of Biochemistry, Genetics and Molecular Biology, and Medicine, with 53 and 30 publications respectively. The scientist's work involves several subfields including Molecular Biology, Immunology, Epidemiology, Physiology, and Neurology.

The main topics of their research cover diverse areas such as Neutrophil, Myeloperoxidase and Oxidative Mechanisms; Redox biology and oxidative stress; Epigenetics and DNA Methylation; Neuroinflammation and Neurodegeneration Mechanisms; S100 Proteins and Annexins; Genomics, phytochemicals, and oxidative stress; and Antimicrobial Resistance in Staphylococcus.

Mark B. Hampton's recent papers include:

  • Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer's disease (2022, Acta Neuropathologica Communications)
  • Faecal Myeloperoxidase as a Biomarker of Endoscopic Activity in Inflammatory Bowel Disease (2022, Journal of Crohn s and Colitis)
  • Evaluating the bactericidal action of hypochlorous acid in culture media (2020, Free Radical Biology and Medicine)
  • Genome-wide impact of hydrogen peroxide on maintenance DNA methylation in replicating cells (2021, Epigenetics & Chromatin)
  • Antimicrobial Activity of Neutrophils Against Mycobacteria (2021, Frontiers in Immunology)

They frequently publish in venues such as Free Radical Biology and Medicine, Journal of Biological Chemistry, Redox Biology, bioRxiv (Cold Spring Harbor Laboratory), and Journal of Leukocyte Biology. Their publishing record includes 8 papers in Free Radical Biology and Medicine, 4 in the Journal of Biological Chemistry, 3 in Redox Biology, 3 in bioRxiv, and 2 in Journal of Leukocyte Biology.

Collaboration is a significant aspect of their work. Frequent co-authors include Nina Dickerhof, Anthony J. Kettle, Christine C. Winterbourn, Paul Pace, and Leon Smyth.

Best Publications

  • Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing.

    Mark B. Hampton;Anthony J. Kettle;Christine C. Winterbourn

  • Thiol chemistry and specificity in redox signaling.

    Christine C. Winterbourn;Mark B. Hampton

  • Reactive Oxygen Species and Neutrophil Function

    Christine C Winterbourn;Anthony J Kettle;Mark B Hampton

  • Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis

    Mark B Hampton;Sten Orrenius

  • Modeling the Reactions of Superoxide and Myeloperoxidase in the Neutrophil Phagosome: IMPLICATIONS FOR MICROBIAL KILLING*

    Christine C. Winterbourn;Mark B. Hampton;John H Livesey;Anthony J. Kettle

  • Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling.

    Andrew G. Cox;Christine C. Winterbourn;Mark B. Hampton

  • Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

    Heather Parker;Mike Dragunow;Mark B. Hampton;Anthony J. Kettle

  • The High Reactivity of Peroxiredoxin 2 with H2O2 Is Not Reflected in Its Reaction with Other Oxidants and Thiol Reagents

    Alexander V. Peskin;Felicia M. Low;Louise N. Paton;Ghassan J. Maghzal

  • Involvement of Caspases in Neutrophil Apoptosis: Regulation by Reactive Oxygen Species

    Bengt Fadeel;Anders Åhlin;Anders Åhlin;Jan-Inge Henter;Jan-Inge Henter;Sten Orrenius;Sten Orrenius

  • Redox Regulation of the Caspases during Apoptosisa

    Mark B. Hampton;Bengt Fadeel;Sten Orrenius

  • Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte

    Felicia M. Low;Mark B. Hampton;Alexander V. Peskin;Christine C. Winterbourn

  • Cytochrome c release and caspase activation in hydrogen peroxide‐ and tributyltin‐induced apoptosis

    Hélène Stridh;Monica Kimland;Dean P. Jones;Sten Orrenius

  • Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils

    M B Hampton;A J Kettle;C C Winterbourn

  • Chlorination of Bacterial and Neutrophil Proteins during Phagocytosis and Killing of Staphylococcus aureus

    Anna L.P. Chapman;Mark B. Hampton;Revathy Senthilmohan;Christine C. Winterbourn

  • Peroxiredoxin 2 and Peroxide Metabolism in the Erythrocyte

    Felicia M. Low;Mark B. Hampton;Christine C. Winterbourn

  • Uptake of Helicobacter pylori outer membrane vesicles by gastric epithelial cells.

    Heather Parker;Kenny Chitcholtan;Mark B. Hampton;Jacqueline I. Keenan

  • Helicobacter pylori outer membrane vesicles modulate proliferation and interleukin-8 production by gastric epithelial cells.

    Salim Ismail;Mark B. Hampton;Jacqueline I. Keenan

  • Peroxiredoxins as biomarkers of oxidative stress

    Rebecca A. Poynton;Mark B. Hampton

  • The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation.

    Andrew G. Cox;Kristin K. Brown;Elias S.J. Arner;Mark B. Hampton

  • Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells.

    James W. Baty;Mark B. Hampton;Christine C. Winterbourn

Frequent Co-Authors

Christine C. Winterbourn
Christine C. Winterbourn University of Otago
Anthony J. Kettle
Anthony J. Kettle University of Otago
Sten Orrenius
Sten Orrenius Karolinska Institute
Elias S.J. Arnér
Elias S.J. Arnér Karolinska Institute
Jürgen Bernhagen
Jürgen Bernhagen Ludwig-Maximilians-Universität München
Juliet A. Gerrard
Juliet A. Gerrard University of Auckland
Mark B. Cannell
Mark B. Cannell University of Bristol
Roland Stocker
Roland Stocker The Heart Research Institute
Michael P. Murphy
Michael P. Murphy University of Cambridge
Mike Dragunow
Mike Dragunow University of Auckland

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