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Biology and Biochemistry

D-Index
66
Citations
16874
World Ranking
8604
National Ranking
666

Overview

Mark B. Cannell is affiliated with the University of Bristol in the United Kingdom. Their research primarily focuses on medicine, biochemistry, genetics, and molecular biology, with specialized work in cardiology and cardiovascular medicine as well as molecular biology. Their studies often address subfields including cellular and molecular neuroscience, spectroscopy, and electrical and electronic engineering.

Cannell's main topics of research cover cardiac electrophysiology and arrhythmias, ion channel regulation and function, neuroscience and neural engineering, ECG monitoring and analysis, mass spectrometry techniques and applications, cardiac arrhythmias and treatments, and electrostatic discharge in electronics.

The scientist has contributed to a number of publications, frequently collaborating with coauthors such as Ewan D. Fowler, Jules C. Hancox, Nan Wang, Ana M. Gómez, and Jolanda van der Velden.

Their notable recent papers include:

  • Arrhythmogenic late Ca 2+ sparks in failing heart cells and their control by action potential configuration, 2020, Proceedings of the National Academy of Sciences
  • Nano-scale morphology of cardiomyocyte t-tubule/sarcoplasmic reticulum junctions revealed by ultra-rapid high-pressure freezing and electron tomography, 2020, Journal of Molecular and Cellular Cardiology
  • Inducing Ito,f and phase 1 repolarization of the cardiac action potential with a Kv4.3/KChIP2.1 bicistronic transgene, 2021, Journal of Molecular and Cellular Cardiology
  • Improved Ca2+ release synchrony following selective modification of Itof and phase 1 repolarization in normal and failing ventricular myocytes, 2022, Journal of Molecular and Cellular Cardiology
  • Compromised repolarization reserve in a murine model of catecholaminergic polymorphic ventricular tachycardia caused by RyR2-R420Q mutation, 2025, Journal of Molecular and Cellular Cardiology

Cannell's publications are frequently found in venues such as the Journal of Molecular and Cellular Cardiology, Biophysical Journal, Proceedings of the National Academy of Sciences, SSRN Electronic Journal, and Cells.

Best Publications

  • Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle

    H Cheng;W J Lederer;Mark B Cannell

  • Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions

    Hong Wan;Helen L. Winton;Christian Soeller;Euan R. Tovey

  • Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.

    A. M. Gómez;H. H. Valdivia;H. Cheng;Miriam R. Lederer

  • The control of calcium release in heart muscle

    Mark B Cannell;Hongwei Cheng;W J Lederer

  • Calcium sparks and [Ca2+]i waves in cardiac myocytes

    H. Cheng;M. R. Lederer;W. J. Lederer;M. B. Cannell

  • Effect of membrane potential changes on the calcium transient in single rat cardiac muscle cells

    Mark B. Cannell;Joshua R. Berlin;William J. Lederer

  • Spatial non-uniformities in [Ca2+]i during excitation-contraction coupling in cardiac myocytes

    M.B. Cannell;H. Cheng;W.J. Lederer

  • Cellular and subcellular heterogeneity of [Ca2+]i in single heart cells revealed by fura-2

    W. G. Wier;M. B. Cannell;J. R Berlin;E. Marban

  • Examination of the Transverse Tubular System in Living Cardiac Rat Myocytes by 2-Photon Microscopy and Digital Image–Processing Techniques

    C. Soeller;M. B. Cannell

  • The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus.

    H. Wan;H. L. Winton;C. Soeller;G. W. Taylor

  • Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes.

    David Baddeley;Isuru D. Jayasinghe;Leo Lam;Sabrina Rossberger

  • Relation Between the Sarcolemmal Ca2+ Current and Ca2+ Sparks and Local Control Theories for Cardiac Excitation-Contraction Coupling

    Luis Fernando Santana;H. Cheng;A. M. Gómez;M. B. Cannell

  • Cellular origins of the transient inward current in cardiac myocytes. Role of fluctuations and waves of elevated intracellular calcium.

    Joshua Berlin;M. B. Cannell;W. J. Lederer

  • Model of calcium movements during activation in the sarcomere of frog skeletal muscle

    M.B. Cannell;D.G. Allen

  • Kinetics, stoichiometry and role of the Na–Ca exchange mechanism in isolated cardiac myocytes

    Lynn M. Crespo;Christopher J. Grantham;Mark B. Cannell

  • Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1.

    H. Wan;H.L. Winton;C. Soeller;D.C. Gruenert

  • Expression of the P2X(2) receptor subunit of the ATP-gated ion channel in the cochlea: implications for sound transduction and auditory neurotransmission.

    Gary D. Housley;Refik Kanjhan;Nicholas P. Raybould;Denise Greenwood

  • NUMERICAL SIMULATION OF LOCAL CALCIUM MOVEMENTS DURING L-TYPE CALCIUM CHANNEL GATING IN THE CARDIAC DIAD

    C. Soeller;M.B. Cannell

  • Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o-

    H. Wan;H.L. Winton;C. Soeller;Geoffrey Stewart

  • Three-Dimensional Distribution of Ryanodine Receptor Clusters in Cardiac Myocytes

    Ye Chen-Izu;Stacey L. McCulle;Chris W. Ward;Christian Soeller

Frequent Co-Authors

W. J. Lederer
W. J. Lederer University of Maryland, Baltimore
Heping Cheng
Heping Cheng Peking University
David R. Garrod
David R. Garrod University of Manchester
Philip J. Thompson
Philip J. Thompson University of Western Australia
Garth J. S. Cooper
Garth J. S. Cooper University of Auckland
David G. Allen
David G. Allen University of Sydney
Jadranka Travas-Sejdic
Jadranka Travas-Sejdic University of Auckland
Donald M. Bers
Donald M. Bers University of California, Davis
Gary D. Housley
Gary D. Housley University of New South Wales
Hui Peng
Hui Peng East China Normal University

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