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Biology and Biochemistry

D-Index
65
Citations
13040
World Ranking
9293
National Ranking
712

Overview

Godfrey L. Smith is affiliated with the University of Glasgow in the United Kingdom. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology, with a strong focus on cardiology and cardiovascular medicine.

The main fields of study for their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these fields, Smith's subfields of study cover:

  • Cardiology and Cardiovascular Medicine
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Emergency Medicine
  • Biomedical Engineering

Their research topics highlight a focus on cardiac and neurological function and regulation, including:

  • Cardiac electrophysiology and arrhythmias
  • Neuroscience and Neural Engineering
  • Ion channel regulation and function
  • Pluripotent Stem Cells Research
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Effects of Exercise
  • Cardiac pacing and defibrillation studies

Frequent co-authors who have collaborated on numerous publications with Smith include:

  • Francis L. Burton
  • Rachel C. Myles
  • Radostin D. Simitev
  • William Fuller
  • Eline Huethorst

Smith's research has been published regularly in several peer-reviewed journals and venues. Their most frequent publication venues are:

  • Cardiovascular Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Pharmacological and Toxicological Methods
  • EP Europace
  • Journal of Molecular and Cellular Cardiology

Recent notable papers by Godfrey L. Smith include:

  • Physiology of intracellular calcium buffering, 2023, Physiological Reviews
  • Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes, 2020, Toxicological Sciences
  • Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations, 2020, Regulatory Toxicology and Pharmacology
  • In vivo grafting of large engineered heart tissue patches for cardiac repair, 2021, JCI Insight
  • ESC working group on cardiac cellular electrophysiology position paper: relevance, opportunities, and limitations of experimental models for cardiac electrophysiology research, 2021, EP Europace

Best Publications

  • Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy.

    Ole Johan Kemi;Marcello Ceci;Ulrik Wisloff;Serena Grimaldi

  • International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment

    Ksenia Blinova;Qianyu Dang;Daniel Millard;Godfrey Smith

  • MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo.

    Luca Sala;Berend J. Van Meer;Leon G.J. Tertoolen;Jeroen Bakkers

  • Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation.

    Peter Kohl;Patrizia Camelliti;Francis L. Burton;Godfrey L. Smith

  • Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias.

    Ksenia Blinova;Jayna Stohlman;Jose Vicente;Jose Vicente;Jose Vicente;Dulciana Chan

  • Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca2+ Control, and SR Ca2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy

    Tomas O. Stølen;Morten Andre Høydal;Ole Johan Kemi;Daniele Catalucci

  • Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells.

    Florian Weinberger;Kaja Breckwoldt;Simon Pecha;Allen Kelly

  • QT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular Electrophysiology

    Mathias Baumert;Alberto Porta;Marc A. Vos;Marek Malik

  • Overexpression of FK506-Binding Protein FKBP12.6 in Cardiomyocytes Reduces Ryanodine Receptor–Mediated Ca2+ Leak From the Sarcoplasmic Reticulum and Increases Contractility

    Jürgen Prestle;Paul M.L. Janssen;Anita P. Janssen;Oliver Zeitz

  • cGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac Myocytes

    Alessandra Stangherlin;Frank Gesellchen;Anna Zoccarato;Anna Terrin

  • S100A1: A regulator of myocardial contractility

    Patrick Most;Juliane Bernotat;Philipp Ehlermann;Sven T. Pleger

  • Aerobic interval training enhances cardiomyocyte contractility and Ca2+ cycling by phosphorylation of CaMKII and Thr-17 of phospholamban

    Ole J. Kemi;Ole J. Kemi;Øyvind Ellingsen;Øyvind Ellingsen;Marcello Ceci;Serena Grimaldi

  • Evidence of intercellular coupling between co‐cultured adult rabbit ventricular myocytes and myofibroblasts

    Lisa Chilton;Wayne R. Giles;Godfrey L. Smith

  • Calcium/calmodulin-dependent protein kinase IIdelta associates with the ryanodine receptor complex and regulates channel function in rabbit heart.

    Susan Currie;Christopher M Loughrey;Margaret-Anne Craig;Godfrey L Smith

  • Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release.

    Xiyuan Lu;Kenneth S Ginsburg;Sarah Kettlewell;Julie B C Bossuyt

  • Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium

    Marta Lemme;Bärbel M. Ulmer;Marc D. Lemoine;Antonia T.L. Zech

  • Heterogeneous changes in action potential and intracellular Ca2+ in left ventricular myocyte sub-types from rabbits with heart failure

    M.A. McIntosh;S.M. Cobbe;G.L. Smith

  • The mechanism of early contractile failure of isolated rat ventricular myocytes subjected to complete metabolic inhibition.

    W J Lederer;C G Nichols;G L Smith

  • The relationship between intracellular calcium and contraction in calcium-overloaded ferret papillary muscles.

    D G Allen;D A Eisner;J S Pirolo;G L Smith

  • Potentiometric measurements of stoichiometric and apparent affinity constants of EGTA for protons and divalent ions including calcium

    Godfrey L. Smith;David J. Miller

Frequent Co-Authors

Ulrik Wisløff
Ulrik Wisløff Norwegian University of Science and Technology
Stuart M. Cobbe
Stuart M. Cobbe University of Glasgow
Gianluigi Condorelli
Gianluigi Condorelli Humanitas University
Jonathan M. Cooper
Jonathan M. Cooper University of Glasgow
David A. Eisner
David A. Eisner University of Manchester
Gerd Hasenfuss
Gerd Hasenfuss University of Göttingen
Thomas Eschenhagen
Thomas Eschenhagen Universität Hamburg
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Stuart A. Nicklin
Stuart A. Nicklin University of Glasgow
W. J. Lederer
W. J. Lederer University of Maryland, Baltimore

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