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Christine A. Iacobuzio-Donahue

Christine A. Iacobuzio-Donahue

D-Index & Metrics

Medicine

D-Index
131
Citations
87287
World Ranking
2352
National Ranking
1326

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Christine A. Iacobuzio-Donahue is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research spans a broad spectrum of topics within medicine and molecular biology, with a strong focus on oncology and cancer research.

The main fields of study for this scientist include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Key subfields cover:

  • Oncology
  • Cancer Research
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Immunology

Their work addresses a variety of topics, particularly:

  • Cancer Genomics and Diagnostics
  • Pancreatic and Hepatic Oncology Research
  • Single-cell and Spatial Transcriptomics
  • Cancer Immunotherapy and Biomarkers
  • Epigenetics and DNA Methylation
  • Genetic factors in colorectal cancer
  • Cancer, Hypoxia, and Metabolism

Christine A. Iacobuzio-Donahue has authored numerous research papers published in prominent journals. Recent papers include:

  • Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells (2020, Cell)
  • Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients (2022, Cell)
  • The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution (2020, Cell)
  • The mutational landscape of normal human endometrial epithelium (2020, Nature)
  • The mutational landscape of human somatic and germline cells (2021, Nature)

The venues in which this scientist frequently publishes include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • Clinical Cancer Research
  • Nature Communications

Frequent collaborators in their research are:

  • Eileen M. O'Reilly
  • Alvin P. Makohon-Moore
  • Shigeaki Umeda
  • Akimasa Hayashi
  • Rajya Kappagantula

In addition to journal articles, Christine A. Iacobuzio-Donahue has contributed to book publications. Notably, they authored a volume titled "Gastrointestinal and Liver Pathology" published by Elsevier BV in 2023.

The scientist has been recognized as a Member of the Association of American Physicians, an honor without a specific recorded year.

Best Publications

  • Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

    Siân Jones;Xiaosong Zhang;D. Williams Parsons;D. Williams Parsons;Jimmy Cheng Ho Lin

  • Genomic analyses identify molecular subtypes of pancreatic cancer

    Bailey P;Chang Dk;Nones K;Nones K;Johns Al

  • Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

    Kenneth P. Olive;Michael A. Jacobetz;Christian J. Davidson;Aarthi Gopinathan;Aarthi Gopinathan

  • Whole genomes redefine the mutational landscape of pancreatic cancer.

    Nicola Waddell;Marina Pajic;Ann Marie Patch;David K. Chang

  • Distant metastasis occurs late during the genetic evolution of pancreatic cancer

    Shinichi Yachida;Siân Jones;Ivana Bozic;Tibor Antal;Tibor Antal

  • A draft map of the human proteome

    Min Sik Kim;Sneha M. Pinto;Derese Getnet;Raja Sekhar Nirujogi

  • Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

    Philip J. Stephens;Chris D. Greenman;Beiyuan Fu;Fengtang Yang

  • Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

    Gina M. DeNicola;Florian A. Karreth;Timothy J. Humpton;Aarthi Gopinathan

  • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

    Andrew V. Biankin;Andrew V. Biankin;Andrew V. Biankin;Nicola Waddell;Karin S. Kassahn;Marie Claude Gingras

  • Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

    Andrew D. Rhim;Andrew D. Rhim;Paul E. Oberstein;Dafydd H. Thomas;Emily T. Mirek

  • Organoid Models of Human and Mouse Ductal Pancreatic Cancer

    Sylvia F. Boj;Chang Il Hwang;Chang Il Hwang;Lindsey A. Baker;Lindsey A. Baker;Iok In Christine Chio;Iok In Christine Chio

  • Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

    Richard A. Moffitt;Raoud Marayati;Elizabeth L. Flate;Keith E. Volmar

  • The patterns and dynamics of genomic instability in metastatic pancreatic cancer

    Peter J. Campbell;Peter J. Campbell;Shinichi Yachida;Laura J. Mudie;Philip J. Stephens

  • Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer.

    Vinod P. Balachandran;Marta Łuksza;Julia N. Zhao;Vladimir Makarov

  • DPC4 Gene Status of the Primary Carcinoma Correlates With Patterns of Failure in Patients With Pancreatic Cancer

    Christine A. Iacobuzio-Donahue;Baojin Fu;Shinichi Yachida;Mingde Luo

  • Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

    Siân Jones;Siân Jones;Ralph H. Hruban;Mihoko Kamiyama;Michael Borges

  • Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.

    Georg Feldmann;Surajit Dhara;Volker Fendrich;Djahida Bedja

  • The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.

    Pedram Razavi;Matthew T. Chang;Guotai Xu;Chaitanya Bandlamudi

  • Notch mediates TGFα-induced changes in epithelial differentiation during pancreatic tumorigenesis

    Yoshiharu Miyamoto;Anirban Maitra;Bidyut Ghosh;Ulrich Zechner

  • Organoid profiling identifies common responders to chemotherapy in pancreatic cancer

    Hervé Tiriac;Pascal Belleau;Dannielle D Engle;Dennis Plenker

Frequent Co-Authors

Ralph H. Hruban
Ralph H. Hruban Johns Hopkins University School of Medicine
Anirban Maitra
Anirban Maitra The University of Texas MD Anderson Cancer Center
Michael Goggins
Michael Goggins Johns Hopkins University
Charles J. Yeo
Charles J. Yeo Thomas Jefferson University
Scott E. Kern
Scott E. Kern Johns Hopkins University
John L. Cameron
John L. Cameron Johns Hopkins University
Elizabeth A. Montgomery
Elizabeth A. Montgomery University of Miami
Christopher L. Wolfgang
Christopher L. Wolfgang New York University
Pedram Argani
Pedram Argani Johns Hopkins University
Alison P. Klein
Alison P. Klein Johns Hopkins University

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