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Biology and Biochemistry

D-Index
53
Citations
10036
World Ranking
16173
National Ranking
1277

Overview

Stuart A. Nicklin is affiliated with the University of Glasgow in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable focus areas in Molecular Biology and Cardiology and Cardiovascular Medicine. Additional subfields include Infectious Diseases, Oncology, and Genetics.

Their work covers a range of main topics including:

  • Signaling Pathways in Disease
  • Cardiac Fibrosis and Remodeling
  • Virus-based gene therapy research
  • CAR-T cell therapy research
  • Viral Infections and Immunology Research
  • Protease and Inhibitor Mechanisms
  • COVID-19 Clinical Research Studies

Nicklin's recent publications demonstrate a focus on cardiovascular research and related biomedical signaling. Key papers include:

  • COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options (2020, Cardiovascular Research)
  • RUNX1: an emerging therapeutic target for cardiovascular disease (2020, Cardiovascular Research)
  • Extracellular vesicle signalling in atherosclerosis (2020, Cellular Signalling)
  • Preclinical models of myocardial infarction: from mechanism to translation (2021, British Journal of Pharmacology)
  • Adenoviral vectors for cardiovascular gene therapy applications: a clinical and industry perspective (2022, Journal of Molecular Medicine)

Frequent collaborators include:

  • Christopher M. Loughrey
  • Eilidh MacDonald
  • Colin Berry
  • Tamara P. Martin
  • Ewan R. Cameron

The most frequent venues for Nicklin's publications are:

  • Cardiovascular Research
  • Cellular Signalling
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Molecular and Cellular Cardiology
  • Preprints.org

Best Publications

  • COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options.

    Tomasz J Guzik;Tomasz J Guzik;Saidi A Mohiddin;Anthony Dimarco;Vimal Patel

  • Adenovirus serotype 5 hexon mediates liver gene transfer

    Simon N. Waddington;John H. McVey;David Bhella;Alan L. Parker

  • Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension

    Sandosh Padmanabhan;Olle Melander;Toby Johnson;Anna Maria Di Blasio

  • Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

    Alan L. Parker;Simon N. Waddington;Campbell G. Nicol;Dmitry M. Shayakhmetov

  • Efficient and Selective AAV2-Mediated Gene Transfer Directed to Human Vascular Endothelial Cells

    Stuart A. Nicklin;Hildegard Buening;Kate L. Dishart;Mahesh de Alwis

  • Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

    Paul N. Reynolds;Stuart A. Nicklin;Lioudmila Kaliberova;Brian G. Boatman

  • The Influence of Adenovirus Fiber Structure and Function on Vector Development for Gene Therapy

    Stuart A. Nicklin;Eugene Wu;Glen R. Nemerow;Andrew H. Baker

  • Targeted gene delivery to vascular tissue in vivo by tropism-modified adeno-associated virus vectors.

    Stephen J. White;Stuart A. Nicklin;Hildegard Büning;M. Julia Brosnan

  • Promoters and control elements: Designing expression cassettes for gene therapy

    E. D. Papadakis;S. A. Nicklin;A. H. Baker;S. J. White

  • Selective targeting of gene transfer to vascular endothelial cells by use of peptides isolated by phage display

    Stuart A. Nicklin;Steve J. White;Sarah J. Watkins;Robert E. Hawkins

  • Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

    Stuart A. Nicklin;Dan J. Von Seggern;Lorraine M. Work;Don C.K. Pek

  • Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

    Raul Alba;Angela C. Bradshaw;Alan L. Parker;David Bhella

  • Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses.

    Lorraine M. Work;Hildegard Büning;Ela Hunt;Stuart A. Nicklin

  • Development of Efficient Viral Vectors Selective for Vascular Smooth Muscle Cells

    Lorraine M Work;Stuart A Nicklin;Nick J.R Brain;Kate L Dishart

  • Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodelling.

    Clare A. McKinney;Caroline Fattah;Christopher M. Loughrey;Graeme Milligan

  • Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

    Lynda Coughlan;Raul Alba;Alan L. Parker;Angela C. Bradshaw

  • Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats.

    Campbell G. Nicol;Delyth Graham;William H. Miller;Stephen J. White

  • Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2.

    Anna Zoccarato;Nicoletta C Surdo;Jan M Aronsen;Laura A Fields

  • Analysis of Cell-Specific Promoters for Viral Gene Therapy Targeted at the Vascular Endothelium

    S A Nicklin;P N Reynolds;M J Brosnan;S J White

  • Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy.

    Stuart A Nicklin;Andrew H Baker

Frequent Co-Authors

Andrew H. Baker
Andrew H. Baker University of Edinburgh
Andy Baker
Andy Baker University of New South Wales
John H. McVey
John H. McVey University of Surrey
Simon N. Waddington
Simon N. Waddington University College London
Anna F. Dominiczak
Anna F. Dominiczak University of Glasgow
Graeme Milligan
Graeme Milligan University of Glasgow
Michael Hallek
Michael Hallek University of Cologne
Nico van Rooijen
Nico van Rooijen Vrije Universiteit Amsterdam
Menzo J. E. Havenga
Menzo J. E. Havenga Batavia Biosciences (Netherlands)
Godfrey L. Smith
Godfrey L. Smith University of Glasgow

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