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Biology and Biochemistry

D-Index
61
Citations
10739
World Ranking
11563
National Ranking
4984

Overview

Floyd H. Chilton is affiliated with the University of Arizona in the United States. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on various subfields including Nutrition and Dietetics, Biochemistry, Molecular Biology, Epidemiology, and Infectious Diseases.

The primary topics of their work include:

  • Fatty Acid Research and Health
  • Lipid metabolism and biosynthesis
  • Diet, Metabolism, and Disease
  • Nutritional Studies and Diet
  • Traumatic Brain Injury Research
  • Diet and metabolism studies
  • COVID-19 Clinical Research Studies

Chilton has published extensively in several venues. The frequent publication platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nutrients
  • The FASEB Journal
  • Frontiers in Nutrition
  • Communications Biology

Recent papers authored or co-authored by Chilton cover diverse aspects of biochemistry, nutrition, and disease mechanisms, such as:

  • Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis, 2020, Molecular Cell
  • Genomics in Personalized Nutrition: Can You "Eat for Your Genes"?, 2020, Nutrients
  • Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality, 2021, Journal of Clinical Investigation
  • FADS genetic and metabolomic analyses identify the ∆5 desaturase (FADS1) step as a critical control point in the formation of biologically important lipids, 2020, Scientific Reports
  • Interpreting Clinical Trials With Omega-3 Supplements in the Context of Ancestry and FADS Genetic Variation, 2022, Frontiers in Nutrition

Their frequent collaborators include Brian Hallmark, Susan Sergeant, Laurel Johnstone, Michael C. Seeds, and Justin M. Snider, with collaboration counts of 24, 14, 13, 13, and 9 papers respectively.

Best Publications

  • 1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine. A common source of platelet-activating factor and arachidonate in human polymorphonuclear leukocytes.

    F H Chilton;J M Ellis;S C Olson;R L Wykle

  • Effect of Dietary Fatty Acids on Inflammatory Gene Expression in Healthy Humans

    Kelly L. Weaver;Priscilla Ivester;Michael Seeds;L. Douglas Case

  • Control of arachidonate levels within inflammatory cells

    Floyd H. Chilton;Alfred N. Fonteh;Marc E. Surette;Massimo Triggiani

  • Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes

    Susan Sergeant;Elaheh Rahbar;Floyd H. Chilton

  • Remodeling of arachidonate-containing phosphoglycerides within the human neutrophil

    F H Chilton;R C Murphy

  • Lipopolysaccharide priming of alveolar macrophages for enhanced synthesis of prostanoids involves induction of a novel prostaglandin H synthase.

    M G O'Sullivan;F H Chilton;E M Huggins;C E McCall

  • Influence of J series prostaglandins on apoptosis and tumorigenesis of breast cancer cells

    Carl E. Clay;Andrew M. Namen;Gen-ichi Atsumi;Mark C. Willingham

  • Cyclooxygenase Metabolism of Endogenous Arachidonic Acid by Cultured Human Tracheal Epithelial Cells

    Laurie Churchill;Floyd H. Chilton;James H. Resau;Rebecca Bascom

  • Dietary Supplementation with γ-Linolenic Acid Alters Fatty Acid Content and Eicosanoid Production in Healthy Humans

    Margaret M. Johnson;Dennis D. Swan;Marc E. Surette;Jane Stegner

  • Platelet activating factor. Stimulation of the lipoxygenase pathway in polymorphonuclear leukocytes by 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine.

    F H Chilton;J T O'Flaherty;C E Walsh;M J Thomas

  • 1-ether-linked phosphoglycerides. Major endogenous sources of arachidonate in the human neutrophil.

    F H Chilton;T R Connell

  • Addition of Eicosapentaenoic Acid to γ-Linolenic Acid–Supplemented Diets Prevents Serum Arachidonic Acid Accumulation in Humans

    J. Brooke Barham;Michelle B. Edens;Alfred N. Fonteh;Margaret M. Johnson

  • Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.

    Susan Sergeant;Christina E. Hugenschmidt;Megan E. Rudock;Julie T. Ziegler

  • Selective acylation of lyso platelet activating factor by arachidonate in human neutrophils.

    F H Chilton;J T O'Flaherty;J M Ellis;C L Swendsen

  • Evidence that secretory phospholipase A2 plays a role in arachidonic acid release and eicosanoid biosynthesis by mast cells.

    A N Fonteh;D A Bass;L A Marshall;M Seeds

  • Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases.

    Floyd H. Chilton;Robert C. Murphy;Bryan A. Wilson;Susan Sergeant

  • The Content of Favorable and Unfavorable Polyunsaturated Fatty Acids Found in Commonly Eaten Fish

    Kelly L. Weaver;Priscilla Ivester;Joshua A. Chilton;Martha D. Wilson

  • Dietary Echium Oil Increases Plasma and Neutrophil Long-Chain (n-3) Fatty Acids and Lowers Serum Triacylglycerols in Hypertriglyceridemic Humans

    Marc E. Surette;Michelle Edens;Floyd H. Chilton;Kenneth M. Tramposch

  • Differential synthesis of 1-acyl-2-acetyl-sn-glycero-3-phosphocholine and platelet-activating factor by human inflammatory cells.

    Massimo Triggiani;Robert P. Schleimer;Jane A. Warner;Floyd H. Chilton;Floyd H. Chilton

  • Antigen-induced generation of lyso-phospholipids in human airways

    Floyd H. Chilton;Francis J. Averill;Walter C. Hubbard;Alfred N. Fonteh

Frequent Co-Authors

Rasika A. Mathias
Rasika A. Mathias Johns Hopkins University
Massimo Triggiani
Massimo Triggiani University of Salerno
Ingo Ruczinski
Ingo Ruczinski Johns Hopkins University
Timothy D. Howard
Timothy D. Howard Wake Forest University
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Robert L. Wykle
Robert L. Wykle Wake Forest University
Kathleen C. Barnes
Kathleen C. Barnes University of Colorado Denver
James M. Samet
James M. Samet Environmental Protection Agency
Joseph T. O'Flaherty
Joseph T. O'Flaherty Wake Forest University
Stephen S. Rich
Stephen S. Rich University of Virginia

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