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Thomas M. McIntyre

Thomas M. McIntyre

D-Index & Metrics

Biology and Biochemistry

D-Index
114
Citations
44781
World Ranking
840
National Ranking
525

Overview

Thomas M. McIntyre is affiliated with the University of Utah in the United States and has contributed extensively to fields intersecting medicine, biochemistry, genetics, and molecular biology. Their research incorporates a strong focus on infectious diseases, molecular biology, neurology, surgery, and genetics.

McIntyre's work spans several key topics, which include:

  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • Glioma Diagnosis and Treatment
  • Cancer, Hypoxia, and Metabolism
  • Venous Thromboembolism Diagnosis and Management
  • Pharmacology and Obesity Treatment
  • Extracellular Vesicles in Disease

Recent significant publications authored or co-authored by McIntyre highlight their contributions across different areas of biomedical research. These include:

  • "Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling," 2023, Cancer Cell
  • "Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk," 2020, UNC Libraries
  • "Effect of aspirin on short-term outcomes in hospitalized patients with COVID-19," 2021, Vascular Medicine
  • "SARS-CoV-2 Receptors are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in COVID-19 Patients," 2020, Research Square
  • "COVID-19 plasma exosomes promote proinflammatory immune responses in peripheral blood mononuclear cells," 2022, Scientific Reports

Research published by McIntyre appears in a range of venues, with a concentration in journals and platforms such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square
  • Vascular Medicine
  • Cancer Cell
  • UNC Libraries

Their collaborations include frequent co-authorship with several researchers, reflecting a network of interdisciplinary partnerships. Notable frequent co-authors include:

  • Scott J. Cameron
  • Anu Aggarwal
  • Keith R. McCrae
  • Matthew Godwin
  • Mina K. Chung

With a specialized focus on clinical and molecular aspects of diseases, McIntyre's research covers infectious and inflammatory processes alongside cancer biology and cardiovascular risk factors. Their work on COVID-19-related clinical studies and long-term effects contributes to an evolving understanding of the pandemic's medical impacts.

Best Publications

  • Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.

    Weifei Zhu;Jill C. Gregory;Elin Org;Jennifer A. Buffa

  • Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

    Jian Guo Geng;Michael P. Bevilacqua;Kevin L. Moore;Thomas M. McIntyre

  • Endothelial cell interactions with granulocytes: tethering and signaling molecules

    Guy A Zimmerman;Stephen M Prescott;Thomas M McIntyre

  • Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines

    David A. Jones;David P. Carlton;Thomas M. McIntyre;Guy A. Zimmerman

  • Activated platelets mediate inflammatory signaling by regulated interleukin 1β synthesis

    Stephan Lindemann;Neal D. Tolley;Dan A. Dixon;Thomas M. McIntyre

  • Platelet-Activating Factor and Related Lipid Mediators

    Stephen M. Prescott;Guy A. Zimmerman;Diana M. Stafforini;Thomas M. McIntyre

  • Platelet-activating factor.

    Stephen M. Prescott;Guy A. Zimmerman;Thomas M. McIntyre

  • Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils.

    Kamala D. Patel;Guy A. Zimmerman;Stephen M. Prescott;Rodger P. McEver

  • Escaping the Nuclear Confines: Signal-Dependent Pre-mRNA Splicing in Anucleate Platelets

    Melvin M. Denis;Neal D. Tolley;Michaeline Bunting;Hansjörg Schwertz

  • Activated platelets signal chemokine synthesis by human monocytes.

    Andrew S. Weyrich;Mark R. Elstad;Mark R. Elstad;Rodger P. McEver;Rodger P. McEver;Thomas M. McIntyre

  • Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils.

    Diane E. Lorant;Kamala D. Patel;Thomas M. McIntyre;Rodger P. McEver

  • Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist

    Thomas M. McIntyre;Aaron V. Pontsler;Adriana R. Silva;Andy St. Hilaire

  • Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect

    William Kutchera;David A. Jones;Norisada Matsunami;Joanna Groden

  • Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor.

    D M Stafforini;T M McIntyre;M E Carter;S M Prescott

  • Intracellular unesterified arachidonic acid signals apoptosis.

    Yang Cao;A. Terrece Pearman;Guy A. Zimmerman;Thomas M. McIntyre

  • Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin

    Stephen M. Prescott;Guy A. Zimmerman;Thomas M. McIntyre

  • Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation.

    Andrew S. Weyrich;Thomas M. McIntyre;Thomas M. McIntyre;Thomas M. McIntyre;Rodger P. McEver;Rodger P. McEver;Stephen M. Prescott

  • Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells

    D. A. Dixon;N. D. Tolley;P. H. King;L. B. Nabors

  • Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion.

    Guy A. Zimmerman;Thomas M. McIntyre;Meena Mehra;Stephen M. Prescott

  • Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

    A D Watson;M Navab;S Y Hama;A Sevanian

Frequent Co-Authors

Guy A. Zimmerman
Guy A. Zimmerman University of Utah
Stephen M. Prescott
Stephen M. Prescott University of Utah
Diana M. Stafforini
Diana M. Stafforini Huntsman Cancer Institute
Andrew S. Weyrich
Andrew S. Weyrich University of Utah
Rodger P. McEver
Rodger P. McEver Oklahoma Medical Research Foundation
Glenn D. Prestwich
Glenn D. Prestwich University of Utah
Robert C. Murphy
Robert C. Murphy University of Colorado Denver
David A. Jones
David A. Jones Australian National University
Hugo C. Castro-Faria-Neto
Hugo C. Castro-Faria-Neto Oswaldo Cruz Foundation
Kei Satoh
Kei Satoh Hirosaki University

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