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Tadaatsu Imaizumi

Tadaatsu Imaizumi

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
16407
World Ranking
15388
National Ranking
1088

Overview

Tadaatsu Imaizumi is affiliated with Hirosaki University in Japan and has contributed extensively to research in the fields of Medicine and Immunology and Microbiology. Their work primarily centers on immune response mechanisms, interferon-related pathways, and inflammatory processes, with applications to systemic lupus erythematosus and renal diseases.

The scientist's research publications highlight an ongoing focus on endothelial cell biology and cytokine signaling. Notable recent papers include:

  • Porphyromonas gingivalis lipopolysaccharide induces interleukin-6 and c-c motif chemokine ligand 2 expression in cultured hCMEC/D3 human brain microvascular endothelial cells (2021, Gerodontology)
  • IFIT Proteins Are Involved in CXCL10 Expression in Human Glomerular Endothelial Cells Treated with a Toll-Like Receptor 3 Agonist (2020, Kidney & Blood Pressure Research)
  • Tryptanthrin suppresses double-stranded RNA-induced CXCL10 expression via inhibiting the phosphorylation of STAT1 in human umbilical vein endothelial cells (2020, Molecular Immunology)
  • Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis (2022, Renal Failure)
  • Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis (2023, Renal Failure)

The main topics covered in their work include:

  • interferon and immune responses
  • Immune Response and Inflammation
  • Systemic Lupus Erythematosus Research
  • Cardiac Valve Diseases and Treatments
  • Renal Diseases and Glomerulopathies
  • Cytokine Signaling Pathways and Interactions
  • Aortic Thrombus and Embolism

Their frequent collaborators demonstrate interdisciplinary teamwork and include:

  • Kazuhiko Seya
  • Shogo Kawaguchi
  • Tomoh Matsumiya
  • Hiroshi Tanaka
  • Jiangli Ding

Publication venues that feature their work often are:

  • Journal of Pharmacological Sciences
  • Molecular Biology Reports
  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Research Square (Research Square)
  • Kidney & Blood Pressure Research

Their scientific output spans multiple relevant subfields, including Immunology, Molecular Biology, Cardiology and Cardiovascular Medicine, Rheumatology, and Oncology. The accumulated research contributions reflect a focus on immunological processes at the cellular and molecular level, frequently linking these to clinical conditions such as lupus nephritis and cardiovascular complications.

Best Publications

  • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.

    Mitsutoshi Yoneyama;Mika Kikuchi;Takashi Natsukawa;Noriaki Shinobu

  • Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity

    Mitsutoshi Yoneyama;Mika Kikuchi;Kanae Matsumoto;Tadaatsu Imaizumi

  • Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.

    Diana M. Stafforini;Kei Satoh;Donald L. Atkinson;Larry W. Tjoelker

  • EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFN.

    Mrinal Samanta;Dai Iwakiri;Teru Kanda;Tadaatsu Imaizumi

  • Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation.

    Min-Jung Kim;Sun-Young Hwang;Tadaatsu Imaizumi;Joo-Yeon Yoo

  • Interferon-γ stimulates the expression of galectin-9 in cultured human endothelial cells

    Tadaatsu Imaizumi;Mika Kumagai;Naoko Sasaki;Hidekachi Kurotaki

  • Galectin-9 in physiological and pathological conditions.

    Mitsuomi Hirashima;Yumiko Kashio;Nozomu Nishi;Akira Yamauchi

  • Regulation of CX3CL1/fractalkine expression in endothelial cells.

    Tadaatsu Imaizumi;Hidemi Yoshida;Kei Satoh

  • Identification of Genes Differentially Expressed in Canine Vasospastic Cerebral Arteries after Subarachnoid Hemorrhage

    Hideaki Onda;Hidetoshi Kasuya;Kintomo Takakura;Tomokatsu Hori

  • Type-III interferon, not type-I, is the predominant interferon induced by respiratory viruses in nasal epithelial cells.

    Tamaki Okabayashi;Takashi Kojima;Tomoyuki Masaki;Shin-ichi Yokota

  • Selective eosinophil adhesion to fibroblast via IFN-gamma-induced galectin-9.

    Hirofumi Asakura;Yumiko Kashio;Kazuhiro Nakamura;Masako Seki

  • A Mutation in Plasma Platelet-Activating Factor Acetylhydrolase (Val279→Phe) is a Genetic Risk Factor for Stroke

    Makoto Hiramoto;Hidemi Yoshida;Tadaatsu Imaizumi;Nobuhiro Yoshimizu

  • Retinoic Acid-Inducible Gene-I Is Induced in Endothelial Cells by LPS and Regulates Expression of COX-2

    Tadaatsu Imaizumi;Satoko Aratani;Toshihiro Nakajima;Mary Carlson

  • Expression of Tumor Necrosis Factor-α in Cultured Human Endothelial Cells Stimulated With Lipopolysaccharide or Interleukin-1α

    Tadaatsu Imaizumi;Hiroyuki Itaya;Kazumi Fujita;Daisuke Kudoh

  • Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population

    Yoshiji Yamada;Hidemi Yoshida;Sahoko Ichihara;Tadaatsu Imaizumi

  • Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes.

    Hidemi Yoshida;Tadaatsu Imaizumi;Koji Fujimoto;Naomi Matsuo

  • Human Endothelial Cells Synthesize ENA-78: Relationship to IL-8 and to Signaling of PMN Adhesion

    Tada Atsu Imaizumi;Kurt H. Albertine;Douglas L. Jicha;Thomas M. McIntyre

  • Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD

    Minying Zhang;Xuefeng Wu;Andrew J. Lee;Andrew J. Lee;Wei Jin

  • Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines.

    Jukka Sirén;Tadaatsu Imaizumi;Devanand Sarkar;Taija Pietilä

  • Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.

    K. Satoh;T.-A. Imaizumi;Y. Kawamura;H. Yoshida

Frequent Co-Authors

Kei Satoh
Kei Satoh Hirosaki University
Koichi Wakabayashi
Koichi Wakabayashi Hirosaki University
Etsuro Ito
Etsuro Ito Hirosaki University
Ken Okumura
Ken Okumura Hirosaki University
Mitsuomi Hirashima
Mitsuomi Hirashima Kagawa University
Ken Itoh
Ken Itoh Hirosaki University
Junsei Mimura
Junsei Mimura Hirosaki University
Takashi Fujita
Takashi Fujita Kyoto University
Hitoshi Takahashi
Hitoshi Takahashi Niigata University
Yukio Kato
Yukio Kato Hiroshima University

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