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Chemistry

D-Index
52
Citations
9808
World Ranking
13496
National Ranking
4

Overview

Ana Denicola is affiliated with the University of the Republic in Uruguay and has an extensive publication record in the fields of biochemistry, genetics, molecular biology, and medicine. Their research spans various subfields, including molecular biology, physiology, biochemistry, cell biology, and spectroscopy.

The main focus of Denicola's scientific contributions lies in the study of redox biology and oxidative stress, a topic reflected in many of their research outputs. Additional primary areas of work include erythrocyte function and pathophysiology, sulfur compounds in biology, lipid membrane structure and behavior, heat shock proteins research, bioluminescence and chemiluminescence research, and studies involving heme oxygenase-1 and carbon monoxide.

Denicola has authored research articles published in various peer-reviewed scientific journals. Selected recent papers include:

  • Oxidants and Antioxidants in the Redox Biochemistry of Human Red Blood Cells, 2022, ACS Omega
  • Oxidative Modification of Proteins: From Damage to Catalysis, Signaling, and Beyond, 2021, Antioxidants and Redox Signaling
  • The multifaceted nature of peroxiredoxins in chemical biology, 2023, Current Opinion in Chemical Biology
  • The permeability of human red blood cell membranes to hydrogen peroxide is independent of aquaporins, 2021, Journal of Biological Chemistry
  • Nitro-fatty acids as activators of hSIRT6 deacetylase activity, 2020, Journal of Biological Chemistry

The venues where Denicola frequently publishes include:

  • Free Radical Biology and Medicine
  • Journal of Biological Chemistry
  • Redox Biochemistry and Chemistry
  • Biophysical Reviews
  • ACS Omega

Denicola collaborates regularly with several researchers, often co-authoring publications with:

  • Matías N. Möller
  • Leonor Thomson
  • Florencia Orrico
  • Sebastián F. Villar
  • Gerardo Ferrer-Sueta

Best Publications

  • Evaluating the antioxidant capacity of natural products: a review on chemical and cellular-based assays.

    Camilo López-Alarcón;Ana Denicola

  • Peroxynitrite Reaction with Carbon Dioxide/Bicarbonate: Kinetics and Influence on Peroxynitrite-Mediated Oxidations

    Ana Denicola;Bruce A. Freeman;Madia Trujillo;Rafael Radi

  • Diffusion of peroxynitrite across erythrocyte membranes

    Ana Denicola;José M. Souza;Rafael Radi

  • Factors Affecting Protein Thiol Reactivity and Specificity in Peroxide Reduction

    Gerardo Ferrer-Sueta;Bruno Manta;Horacio Botti;Rafael Radi

  • Protein tryptophan accessibility studied by fluorescence quenching

    Matías Möller;Ana Denicola

  • Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest.

    Sebastián Carballal;Madia Trujillo;Ernesto Cuevasanta;Silvina Bartesaghi

  • The peroxidase and peroxynitrite reductase activity of human erythrocyte peroxiredoxin 2.

    Bruno Manta;Martín Hugo;Cecilia Ortiz;Gerardo Ferrer-Sueta

  • Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi.

    A. Denicola;H. Rubbo;D. Rodriguez;R. Radi

  • Nitric Oxide Diffusion in Membranes Determined by Fluorescence Quenching

    Ana Denicola;José M. Souza;Rafael Radi;Eduardo Lissi

  • Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets.

    Lucía Otero;Marisol Vieites;Lucía Boiani;Ana Denicola

  • Peroxynitrite and drug-dependent toxicity.

    Ana Denicola;Rafael Radi

  • 1,2,5-Oxadiazole N-oxide derivatives and related compounds as potential antitrypanosomal drugs: structure-activity relationships.

    H. Cerecetto;R. Di Maio;M. Gonzalez;M. Risso

  • Direct Measurement of Nitric Oxide and Oxygen Partitioning into Liposomes and Low Density Lipoprotein

    Matías Möller;Horacio Botti;Carlos Batthyany;Homero Rubbo

  • Mode of action of Nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: Is oxidative stress involved?

    Mariana Boiani;Lucia Piacenza;Paola Hernández;Lucia Boiani

  • Detection and quantification of nitric oxide-derived oxidants in biological systems.

    Matías N. Möller;Natalia Rios;Madia Trujillo;Rafael Radi

  • Reaction of Human Hemoglobin with Peroxynitrite ISOMERIZATION TO NITRATE AND SECONDARY FORMATION OF PROTEIN RADICALS

    Natalia Romero;Rafael Radi;Edlaine Linares;Ohara Augusto

  • In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones.

    Gabriela Aguirre;Lucı́a Boiani;Hugo Cerecetto;Marcelo Fernández

  • Peroxynitrite reactions with carbon dioxide-bicarbonate.

    Rafael Radi;Ana Denicola;Bruce A. Freeman

  • Peroxynitrite Inactivates Thiol-Containing Enzymes of Trypanosoma cruzi Energetic Metabolism and Inhibits Cell Respiration

    H. Rubbo;A. Denicola;R. Radi

  • Solubility and Permeation of Hydrogen Sulfide in Lipid Membranes

    Ernesto Cuevasanta;Ana Denicola;Beatriz Alvarez;Matías N. Möller

  • Diffusion of peroxynitrite in the presence of carbon dioxide.

    Natalia Romero;Ana Denicola;José M. Souza;Rafael Radi

  • The Biological Chemistry of Peroxynitrite

    Rafael Radi;Ana Denicola;Beatriz Alvarez;Gerardo Ferrer-Sueta

Frequent Co-Authors

Rafael Radi
Rafael Radi University of the Republic
Mercedes González
Mercedes González University of the Republic
Hugo Cerecetto
Hugo Cerecetto University of the Republic
Beatriz Alvarez
Beatriz Alvarez University of the Republic
Madia Trujillo
Madia Trujillo University of the Republic
Ohara Augusto
Ohara Augusto Universidade de São Paulo
Bruce A. Freeman
Bruce A. Freeman University of Pittsburgh
Jack R. Lancaster
Jack R. Lancaster University of Pittsburgh
Leslie B. Poole
Leslie B. Poole Wake Forest University
Pedro M. Alzari
Pedro M. Alzari Institut Pasteur

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