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D-Index & Metrics

Chemistry

D-Index
60
Citations
18124
World Ranking
9548
National Ranking
2683

Overview

Jack R. Lancaster is affiliated with the University of Pittsburgh in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their publications cover a range of topics including sulfur compounds in biology, inhalation and respiratory drug delivery, nitric oxide and endothelin effects, polyamine metabolism, drug transport and resistance mechanisms, ion channel regulation, and amino acid enzymes and metabolism.

Their recent papers include:

  • Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis, 2020, Nature Communications
  • Historical origins of the discovery of mammalian nitric oxide (nitrogen monoxide) production/physiology/pathophysiology, 2020, Biochemical Pharmacology
  • The Role of Host-Generated H2S in Microbial Pathogenesis: New Perspectives on Tuberculosis, 2020, Frontiers in Cellular and Infection Microbiology
  • Mycobacterium tuberculosis H2S Functions as a Sink to Modulate Central Metabolism, Bioenergetics, and Drug Susceptibility, 2021, Antioxidants
  • Quantitation of spin probe-detectable oxidants in cells using electron paramagnetic resonance spectroscopy: To probe or to trap?, 2020, Free Radical Biology and Medicine

Frequent co-authors of Lancaster include:

  • Joel N. Glasgow
  • Adrie J. C. Steyn
  • Ritesh Rajesh Sevalkar
  • Vineel P. Reddy
  • Md. Aejazur Rahman

They regularly publish in the following venues:

  • Free Radical Biology and Medicine
  • Redox Biology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Biochemical Pharmacology

In terms of research subfields, their work spans biochemistry, molecular biology, pulmonary and respiratory medicine, physiology, and oncology.

Main topics covered in their research include:

  • Sulfur Compounds in Biology
  • Inhalation and Respiratory Drug Delivery
  • Nitric Oxide and Endothelin Effects
  • Polyamine Metabolism and Applications
  • Drug Transport and Resistance Mechanisms
  • Ion channel regulation and function
  • Amino Acid Enzymes and Metabolism

Best Publications

  • The biological lifetime of nitric oxide: Implications for the perivascular dynamics of NO and O2

    Douglas D. Thomas;Xiaoping Liu;Stephen P. Kantrow;Jack R. Lancaster

  • Accelerated reaction of nitric oxide with O2 within the hydrophobic interior of biological membranes

    Xiaoping Liu;Mark J. S. Miller;Mahesh S. Joshi;Douglas D. Thomas

  • Aminoguanidine, a Novel Inhibitor of Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction

    John A. Corbett;Ronald G. Tilton;Kathy Chang;Khalid S. Hasan

  • Nitrate and nitrite in biology, nutrition and therapeutics

    Jon O Lundberg;Mark T Gladwin;Amrita Ahluwalia;Nigel Benjamin

  • The emerging biology of the nitrite anion

    Mark T Gladwin;Alan N Schechter;Daniel B Kim-Shapiro;Rakesh P Patel

  • EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.

    J R Lancaster;J B Hibbs

  • Simulation of the diffusion and reaction of endogenously produced nitric oxide.

    Unknown

  • Diffusion-limited Reaction of Free Nitric Oxide with Erythrocytes

    Xiaoping Liu;Mark J.S. Miller;Mahesh S. Joshi;Halina Sadowska-Krowicka

  • Quantitation of nitrate and nitrite in extracellular fluids

    Matthew B. Grisham;Glenda G. Johnson;Jack R. Lancaster

  • A Tutorial on the Diffusibility and Reactivity of Free Nitric Oxide

    Unknown

  • Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues.

    Jeannette E. Doeller;T. Scott Isbell;Gloria Benavides;Jeffrey Koenitzer

  • Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor.

    Ashwani Kumar;Jose C. Toledo;Rakesh P. Patel;Jack R. Lancaster

  • Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide.

    J. A. Corbett;Jin Lin Wang;M. A. Sweetland;J. R. Lancaster

  • Chemical foundations of hydrogen sulfide biology.

    Qian Li;Jack R. Lancaster

  • Nitric oxide's reactions with hemoglobin: a view through the SNO-storm

    Mark T. Gladwin;Jack R. Lancaster;Bruce A. Freeman;Alan N. Schechter

  • What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology.

    Bradford G. Hill;Brian P. Dranka;Shannon M. Bailey;Jack R. Lancaster

  • Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide

    MA Schwarz;JS Lazo;JC Yalowich;WP Allen

  • Loss and Degradation of Enzyme-bound Heme Induced by Cellular Nitric Oxide Synthesis

    Young-Myeong Kim;Hector A. Bergonia;Claudia Müller;Bruce R. Pitt

  • Nitrogen oxide-induced autoprotection in isolated rat hepatocytes

    Young-Myeong Kim;Hector Bergonia;Jack R. Lancaster

  • Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions.

    Mahesh S. Joshi;T. Bruce Ferguson;Tae H. Han;Daniel R. Hyduke

  • Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate

    Zili Zhang;Peter Oliver;Jack R. Jr. Lancaster;Paul O. Schwarzenberger

  • Steroidogenic electron transport in adrenal cortex mitochondria.

    Lambeth Jd;Seybert Dw;Lancaster;Salerno Jc

  • Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation from nitric oxide

    Charles A. Bosworth;José C. Toledo;Jaroslaw W. Zmijewski;Qian Li

  • Hydrogen sulfide mediates vasoactivity in an O2-dependent manner.

    Jeffrey R. Koenitzer;T. Scott Isbell;Hetal D. Patel;Gloria A. Benavides

Frequent Co-Authors

Bruce A. Freeman
Bruce A. Freeman University of Pittsburgh
Sadis Matalon
Sadis Matalon University of Alabama at Birmingham
John A. Corbett
John A. Corbett Medical College of Wisconsin
Jaroslaw W. Zmijewski
Jaroslaw W. Zmijewski University of Alabama at Birmingham
Ana Denicola
Ana Denicola University of the Republic
Michael L. McDaniel
Michael L. McDaniel Washington University in St. Louis
Francisco J. Schopfer
Francisco J. Schopfer University of Pittsburgh
Amit Gaggar
Amit Gaggar University of Alabama at Birmingham
Victor M. Darley-Usmar
Victor M. Darley-Usmar University of Alabama at Birmingham
Mark T. Dransfield
Mark T. Dransfield University of Alabama at Birmingham

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