Michael L. McDaniel focuses on Endocrinology, Internal medicine, Nitric oxide, Nitric oxide synthase and Biochemistry. His research in Endocrinology intersects with topics in Interleukin and Signal transduction. His study in Internal medicine is interdisciplinary in nature, drawing from both P70-S6 Kinase 1, Arachidonic acid and Intracellular.
His study in the field of Omega-N-Methylarginine is also linked to topics like Nitrite. His work carried out in the field of Nitric oxide synthase brings together such families of science as Tumor necrosis factor alpha, Cytokine, Diabetes mellitus, Molecular biology and Enzyme inhibitor. He focuses mostly in the field of Insulin, narrowing it down to topics relating to Secretion and, in certain cases, Endoplasmic reticulum.
His primary areas of study are Internal medicine, Endocrinology, Insulin, Islet and Biochemistry. His is doing research in Pancreatic islets, Secretion, Nitric oxide, Nitric oxide synthase and Cytokine, both of which are found in Internal medicine. His Nitric oxide formation study in the realm of Nitric oxide interacts with subjects such as Nitrite.
In Nitric oxide synthase, Michael L. McDaniel works on issues like Interleukin, which are connected to Insulitis. His Endocrinology study incorporates themes from Signal transduction and Intracellular. The various areas that Michael L. McDaniel examines in his Islet study include Extracellular, Cell biology, Calcium and Caffeine.
His main research concerns Endocrinology, Internal medicine, Insulin, Cell biology and Insulin resistance. In his study, which falls under the umbrella issue of Endocrinology, Pancreatic islets and Intracellular is strongly linked to Lipoprotein lipase. His Internal medicine research focuses on P70-S6 Kinase 1 and how it connects with Leucine.
His work on PI3K/AKT/mTOR pathway, Wnt signaling pathway and Protein kinase B as part of general Cell biology study is frequently linked to Cell phenotype and MSDC, bridging the gap between disciplines. In the field of Islet, his study on Insulin oscillation overlaps with subjects such as Lipid Droplet Associated Proteins. Michael L. McDaniel combines subjects such as Molecular biology, Nitric oxide synthase, Nitric oxide and Protease with his study of Phosphorylation.
The scientist’s investigation covers issues in Biochemistry, Phosphorylation, Insulin receptor, Endocrinology and Internal medicine. His research in Phosphorylation tackles topics such as Kinase which are related to areas like Adenylyl cyclase and Diazoxide. The subject of his Insulin receptor research is within the realm of Insulin.
His studies in Endocrinology integrate themes in fields like Signal transduction, Cell biology and P70-S6 Kinase 1. His studies deal with areas such as Molecular biology, Nitric oxide synthase, Nitric oxide and Protease as well as Signal transduction. Michael L. McDaniel has researched Protein phosphorylation in several fields, including Amino acid, Transamination, Beta cell and GRB10.
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Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.
Thomas P. Misko;William M. Moore;Thomas P. Kasten;G.Allen Nickols.
European Journal of Pharmacology (1993)
Aminoguanidine, a Novel Inhibitor of Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction
John A. Corbett;Ronald G. Tilton;Kathy Chang;Khalid S. Hasan.
Diabetes (1992)
Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.
John A. Corbett;Michael A. Sweetland;Jin Lin Wang;Jack R. Lancaster.
Proceedings of the National Academy of Sciences of the United States of America (1993)
Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM.
John A Corbett;Michael L McDaniel.
Diabetes (1992)
Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.
Ronald G Tilton;Katherine Chang;Khalid S Hasan;Samuel R Smith.
Diabetes (1993)
Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide.
J. A. Corbett;Jin Lin Wang;M. A. Sweetland;J. R. Lancaster.
Journal of Clinical Investigation (1992)
A metabolite-regulated potassium channel in rat pancreatic B cells.
Stanley Misler;Lee C. Falke;Kevin Gillis;Michael L. McDaniel.
Proceedings of the National Academy of Sciences of the United States of America (1986)
Intracellular Ca2+ mobilization by arachidonic acid. Comparison with myo-inositol 1,4,5-trisphosphate in isolated pancreatic islets.
B A Wolf;J Turk;W R Sherman;M L McDaniel.
Journal of Biological Chemistry (1986)
Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion.
J A Corbett;J R Lancaster;M A Sweetland;M L McDaniel.
Journal of Biological Chemistry (1991)
Cytokines and nitric oxide in islet inflammation and diabetes.
Michael L. McDaniel;Guim Kwon;Jeanette R. Hill;Connie A. Marshall.
Experimental Biology and Medicine (1996)
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