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Flemming Pociot

Flemming Pociot

D-Index & Metrics

Genetics

D-Index
80
Citations
25552
World Ranking
1575
National Ranking
16

Medicine

D-Index
81
Citations
26976
World Ranking
16530
National Ranking
181

Overview

Flemming Pociot is affiliated with the Steno Diabetes Center in Denmark and has an extensive publication record primarily focused on diabetes and related metabolic disorders. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology.

The main fields of study represented in Pociot's work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields frequently addressed in their publications comprise:

  • Genetics
  • Surgery
  • Endocrinology, Diabetes and Metabolism
  • Molecular Biology
  • Immunology

The primary topics of Pociot's research focus on diabetes and associated disorders, including:

  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Diabetes Management and Research
  • MicroRNA in disease regulation
  • Extracellular vesicles in disease
  • Diet, Metabolism, and Disease
  • Inflammatory Bowel Disease

Pociot has contributed notably to scientific knowledge through recent publications such as:

  • "Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes" (2021) in Nature Genetics
  • "Anti-diabetic potential of plant alkaloids: Revisiting current findings and future perspectives" (2020) in Pharmacological Research
  • "Human pathways in animal models: possibilities and limitations" (2021) in Nucleic Acids Research
  • "Low-grade inflammation in type 2 diabetes: a cross-sectional study from a Danish diabetes outpatient clinic" (2022) in BMJ Open
  • "Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes" (2020) in bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors collaborating with Pociot include:

  • Reza Yarani
  • Simranjeet Kaur
  • Joachim Størling
  • Jesper Johannesen
  • Cristina Legido-Quigley

The scientist's work has been published in a variety of venues, with multiple papers appearing in:

  • Diabetologia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • Diabetes/Metabolism Research and Reviews
  • Pediatric Diabetes

Best Publications

  • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

    Jeffrey C Barrett;David G Clayton;Patrick Concannon;Beena Akolkar

  • A Taql polymorphism in the human interleukin-1β (IL-1β) gene correlates with IL-1β secretion in vitro

    F. Pociot;J. Mølvig;L. Wogensen;H. Worsaae

  • A human phenome-interactome network of protein complexes implicated in genetic disorders

    Kasper Lage;E Olof Karlberg;Zenia M Størling;Páll Í Ólason

  • Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

    Bennett;A M Lucassen;S C Gough;E E Powell

  • An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles.

    A. G. Wilson;N. De Vries;F. Pociot;F. S. Di Giovine

  • Cytokine gene polymorphism in human disease: on-line databases.

    J Bidwell;L Keen;G Gallagher;R Kimberly

  • Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-a and TNF-0 by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus

    Flemming Pociot;Laurence Briant;Cornelis Jongeneel;Jens Mölvig

  • CTLA-4 in autoimmune diseases--a general susceptibility gene to autoimmunity?

    OP Kristiansen;ZM Larsen;F Pociot

  • Genetic risk factors for type 1 diabetes

    Flemming Pociot;Åke Lernmark

  • Genetics of type 1 diabetes mellitus

    F Pociot;M F McDermott

  • Genetics of Type 1 Diabetes: What's Next?

    Flemming Pociot;Beena Akolkar;Patrick Concannon;Henry A. Erlich

  • Cytokine gene polymorphism in human disease: on-line databases, Supplement 1

    J Bidwell;L Keen;G Gallagher;R Kimberly

  • Circulating Levels of MicroRNA from Children with Newly Diagnosed Type 1 Diabetes and Healthy Controls: Evidence That miR-25 Associates to Residual Beta-Cell Function and Glycaemic Control during Disease Progression

    Lotte B. Nielsen;Cheng Wang;Kaspar Sorensen;Claus Heiner Bang-Berthelsen

  • Cytokine gene polymorphism in human disease: on-line databases, supplement 2.

    N Haukim;J L Bidwell;A J P Smith;L J Keen

  • Type 1 Diabetes: Evidence for Susceptibility Loci from Four Genome-Wide Linkage Scans in 1,435 Multiplex Families

    Patrick Concannon;Henry A. Erlich;Cecile Julier;Grant Morahan

  • On the pathogenesis of IDDM

    J. Nerup;T. Mandrap-Poulsen;S. Helqvist;H. U. Andersen

  • Cytokine and free radicals as effector molecules in the destruction of pancreatic beta cells.

    Mandrup-Poulsen T;Helqvist S;Wogensen Ld;Mølvig J

  • A tumour necrosis factor beta gene polymorphism in relation to monokine secretion and insulin-dependent diabetes mellitus.

    F Pociot;J. Mølvig;L. Wogensen;H. Worsaae

  • Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele

    Simon T. Bennett;Amanda J. Wilson;Laura Esposito;Nourdine Bouzekri

  • IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus.

    Simon T. Bennett;Amanda J. Wilson;Francesco Cucca;Jørn Nerup

Frequent Co-Authors

Jørn Nerup
Jørn Nerup Steno Diabetes Center
Thomas Mandrup-Poulsen
Thomas Mandrup-Poulsen University of Copenhagen
John A. Todd
John A. Todd University of Oxford
Grant Morahan
Grant Morahan Harry Perkins Institute of Medical Research
Patrick Concannon
Patrick Concannon University of Florida
Oluf Pedersen
Oluf Pedersen University of Copenhagen
Stephen S. Rich
Stephen S. Rich University of Virginia
Henry A. Erlich
Henry A. Erlich UCSF Benioff Children's Hospital
Åke Lernmark
Åke Lernmark Lund University
Søren Brunak
Søren Brunak University of Copenhagen

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