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Chemistry

D-Index
53
Citations
7717
World Ranking
13303
National Ranking
2078

Overview

Xingshu Li is affiliated with Sun Yat-sen University in China, focusing their research on engineering, materials science, and medicine. Their scholarly work predominantly centers on biomedical engineering, pulmonary and respiratory medicine, and materials chemistry, reflecting an interdisciplinary approach relevant to both applied and clinical sciences.

Their research topics cover a wide range of specialized areas including nanoplatforms for cancer theranostics, photodynamic therapy research studies, and porphyrin and phthalocyanine chemistry. Further topics of interest are luminescence and fluorescent materials, photoacoustic and ultrasonic imaging, nanoparticle-based drug delivery, and advanced nanomaterials in catalysis.

Frequent publication venues for Li's research include:

  • Dyes and Pigments
  • Chemical Science
  • ACS Applied Materials & Interfaces
  • Angewandte Chemie International Edition
  • Angewandte Chemie

Among their most cited papers are:

  • "Clinical development and potential of photothermal and photodynamic therapies for cancer" (2020) published in Nature Reviews Clinical Oncology
  • "Organelle-Targeted Photosensitizers for Precision Photodynamic Therapy" (2021) published in ACS Applied Materials & Interfaces
  • "Nanostructured Phthalocyanine Assemblies with Efficient Synergistic Effect of Type I Photoreaction and Photothermal Action to Overcome Tumor Hypoxia in Photodynamic Therapy" (2021) published in Journal of the American Chemical Society
  • "Phthalocyanines as contrast agents for photothermal therapy" (2020) published in Coordination Chemistry Reviews
  • "Supramolecular agents for combination of photodynamic therapy and other treatments" (2021) published in Chemical Science

Xingshu Li collaborates frequently with several researchers, including:

  • Juyoung Yoon
  • Jian-Dong Huang
  • Mei-Rong Ke
  • Biyuan Zheng
  • Zixuan Chen

The scientist's work has a strong focus on developing and improving therapeutic strategies for cancer, especially exploring photothermal and photodynamic therapies. Their contributions to nanoplatforms and photosensitizer technologies are linked closely to precision medicine and multidimensional treatment approaches. This cross-disciplinary research integrates advanced materials chemistry with medical applications.

Best Publications

  • Palladium-catalyzed oxidative C-H bond coupling of steered acetanilides and aldehydes: a facile access to ortho-acylacetanilides.

    Yinuo Wu;Baozhu Li;Fei Mao;Xingshu Li

  • Design, Synthesis, and Evaluation of Multitarget-Directed Resveratrol Derivatives for the Treatment of Alzheimer’s Disease

    Chuanjun Lu;Yueyan Guo;Jun Yan;Zonghua Luo

  • Multitarget-Directed Benzylideneindanone Derivatives: Anti-β-Amyloid (Aβ) Aggregation, Antioxidant, Metal Chelation, and Monoamine Oxidase B (MAO-B) Inhibition Properties against Alzheimer’s Disease

    Ling Huang;Chuanjun Lu;Yang Sun;Fei Mao

  • Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo.

    Jun Yan;Jie Chen;Shun Zhang;Jinhui Hu

  • Highly enantioselective alkynylzinc addition to aromatic aldehydes catalyzed by self-assembled titanium catalysts.

    Xingshu Li;Gui Lu;Wai Him Kwok;Albert S C Chan

  • Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer's Disease Based on the Fusion of Donepezil and Ebselen

    Zonghua Luo;Jianfei Sheng;Yang Sun;Chuanjun Lu

  • Synthesis and application of new chiral catalysts for asymmetric alkynylation reactions

    Gui Lu;Yue-Ming Li;Xing-Shu Li;Albert S.C. Chan

  • Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents

    Yanqing Pang;Baijiao An;Lanlan Lou;Junsheng Zhang

  • Enantioselective Alkynylation of Aromatic Ketones Catalyzed by Chiral Camphorsulfonamide Ligands

    Gui Lu;Xingshu Li;Xian Jia;Wing Lai Chan

  • Titanium-catalyzed enantioselective alkynylation of aldehydes.

    Gui Lu;Xingshu Li;Wing Lai Chan;Albert S. C. Chan

  • Design, Synthesis, and Evaluation of Orally Available Clioquinol-Moracin M Hybrids as Multitarget-Directed Ligands for Cognitive Improvement in a Rat Model of Neurodegeneration in Alzheimer’s Disease

    Zhiren Wang;Yali Wang;Bo Wang;Wenrui Li

  • Design, synthesis, and evaluation of multitarget-directed selenium-containing clioquinol derivatives for the treatment of Alzheimer's disease.

    Zhiren Wang;Yali Wang;Wenrui Li;Fei Mao

  • A novel series of tacrine-selegiline hybrids with cholinesterase and monoamine oxidase inhibition activities for the treatment of Alzheimer's disease.

    Chuanjun Lu;Qi Zhou;Jun Yan;Zhiyun Du

  • Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.

    Ling Huang;Anding Shi;Feng He;Xingshu Li

  • Enantioselective alkynylation of aromatic aldehydes catalyzed by new chiral amino alcohol-based ligands

    Gui Lu;Xingshu Li;Zhongyuan Zhou;Wing Lai Chan

  • Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents.

    Fan-Chao Meng;Fei Mao;Wen-Jun Shan;Fangfei Qin

  • New multi-target-directed small molecules against Alzheimer's disease: a combination of resveratrol and clioquinol

    Fei Mao;Jun Yan;Jianheng Li;Xian Jia

  • Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation

    Wen-Jun Shan;Ling Huang;Qi Zhou;Fan-Chao Meng

  • Design, Synthesis, and Evaluation of Orally Bioavailable Quinoline–Indole Derivatives as Innovative Multitarget-Directed Ligands: Promotion of Cell Proliferation in the Adult Murine Hippocampus for the Treatment of Alzheimer’s Disease

    Zhiren Wang;Zhiren Wang;Jinhui Hu;Xiaoping Yang;Xing Feng

  • Benzenediol-berberine hybrids: Multifunctional agents for Alzheimer’s disease

    Huailei Jiang;Xu Wang;Ling Huang;Zonghua Luo

  • Natural products as sources of new lead compounds for the treatment of Alzheimer's disease.

    Ling Huang;Tao Su;Xingshu Li

Frequent Co-Authors

Chao-Jun Li
Chao-Jun Li McGill University
Albert S. C. Chan
Albert S. C. Chan Sun Yat-sen University
Tamio Hayashi
Tamio Hayashi National Taiwan Normal University
Ruihu Wang
Ruihu Wang Chinese Academy of Sciences
Fuk Yee Kwong
Fuk Yee Kwong Chinese University of Hong Kong
Alfred King-Yin Lam
Alfred King-Yin Lam Griffith University
Rong Cao
Rong Cao Chinese Academy of Sciences
Wai-Kwok Wong
Wai-Kwok Wong Hong Kong Baptist University
Maochun Hong
Maochun Hong Chinese Academy of Sciences
Xin Cui
Xin Cui Chinese Academy of Sciences

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