His primary areas of investigation include Biochemistry, IC50, Antioxidant, Acetylcholinesterase and Pharmacology. Biochemistry is closely attributed to Selenium in his study. His work is dedicated to discovering how IC50, Aché are connected with Tacrine, Cholinesterase and Berberine and other disciplines.
His research investigates the connection between Antioxidant and topics such as Clioquinol that intersect with issues in Pharmacophore, Neuroprotection and Protein aggregation. Specifically, his work in Acetylcholinesterase is concerned with the study of Butyrylcholinesterase. His Trolox study which covers Combinatorial chemistry that intersects with Resveratrol.
Xingshu Li mostly deals with Catalysis, Biochemistry, Organic chemistry, Stereochemistry and IC50. His work deals with themes such as Medicinal chemistry, Chirality and Polymer chemistry, which intersect with Catalysis. He frequently studies issues relating to Clioquinol and Biochemistry.
His study in Stereochemistry is interdisciplinary in nature, drawing from both Design synthesis, Peroxide and Pyridine. His IC50 study integrates concerns from other disciplines, such as Acetylcholinesterase, Aché, Matrix metalloproteinase and Pharmacology. His research in Aché intersects with topics in Cholinesterase and Tacrine.
Xingshu Li spends much of his time researching Biochemistry, Apoptosis, Intracellular, IC50 and Pharmacology. His work in the fields of Biochemistry, such as In vitro, intersects with other areas such as Linker. The Apoptosis study combines topics in areas such as HeLa, Selenium and Membrane potential.
Xingshu Li has included themes like Acetylcholinesterase, Aché, Epidermal growth factor receptor, Chelation and Pyrimidine in his IC50 study. Xingshu Li combines subjects such as Design synthesis, Stereochemistry and Tacrine with his study of Aché. The Pharmacodynamics, Oral administration, Pharmacokinetics and Bioavailability research he does as part of his general Pharmacology study is frequently linked to other disciplines of science, such as Inhibitory postsynaptic potential, therefore creating a link between diverse domains of science.
Cell growth, In vitro, Biochemistry, Intracellular and Pharmacology are his primary areas of study. His In vitro study combines topics in areas such as Apoptosis, Cell, Oxygen radical absorbance capacity and Antimitotic Agent. His study deals with a combination of Biochemistry and Histone deacetylase.
His Intracellular research is multidisciplinary, relying on both Rolipram, Phosphodiesterase, Clioquinol and Antioxidant capacity. His work is connected to Oral administration, Pharmacokinetics, Bioavailability, Neuroprotection and Pharmacodynamics, as a part of Pharmacology. Many of his studies on Oral administration involve topics that are commonly interrelated, such as Antioxidant.
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Palladium-catalyzed oxidative C-H bond coupling of steered acetanilides and aldehydes: a facile access to ortho-acylacetanilides.
Yinuo Wu;Baozhu Li;Fei Mao;Xingshu Li.
Organic Letters (2011)
Design, Synthesis, and Evaluation of Multitarget-Directed Resveratrol Derivatives for the Treatment of Alzheimer’s Disease
Chuanjun Lu;Yueyan Guo;Jun Yan;Zonghua Luo.
Journal of Medicinal Chemistry (2013)
Highly enantioselective alkynylzinc addition to aromatic aldehydes catalyzed by self-assembled titanium catalysts.
Xingshu Li;Gui Lu;Wai Him Kwok;Albert S C Chan.
Journal of the American Chemical Society (2002)
Enantioselective Alkynylation of Aromatic Ketones Catalyzed by Chiral Camphorsulfonamide Ligands
Gui Lu;Xingshu Li;Xian Jia;Wing Lai Chan.
Angewandte Chemie (2003)
Multitarget-Directed Benzylideneindanone Derivatives: Anti-β-Amyloid (Aβ) Aggregation, Antioxidant, Metal Chelation, and Monoamine Oxidase B (MAO-B) Inhibition Properties against Alzheimer’s Disease
Ling Huang;Chuanjun Lu;Yang Sun;Fei Mao.
Journal of Medicinal Chemistry (2012)
Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer's Disease Based on the Fusion of Donepezil and Ebselen
Zonghua Luo;Jianfei Sheng;Yang Sun;Chuanjun Lu.
Journal of Medicinal Chemistry (2013)
Titanium-catalyzed enantioselective alkynylation of aldehydes.
Gui Lu;Xingshu Li;Wing Lai Chan;Albert S. C. Chan.
Chemical Communications (2002)
Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo.
Jun Yan;Jie Chen;Shun Zhang;Jinhui Hu.
Journal of Medicinal Chemistry (2016)
Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents
Yanqing Pang;Baijiao An;Lanlan Lou;Junsheng Zhang.
Journal of Medicinal Chemistry (2017)
Enantioselective alkynylation of aromatic aldehydes catalyzed by new chiral amino alcohol-based ligands
Gui Lu;Xingshu Li;Zhongyuan Zhou;Wing Lai Chan.
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