Razqallah Hakem

Overview

Best Publications

• Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

  Nicholas Joza;Nicholas Joza;Santos A. Susin;Eric Daugas;William L. Stanford

  1919
  Citations

• Differential requirement for caspase 9 in apoptotic pathways in vivo

  Razqallah Hakem;Razqallah Hakem;Anne Hakem;Anne Hakem;Gordon S Duncan;Gordon S Duncan;Jeffrey T Henderson

  1660
  Citations

• Apaf1 is required for mitochondrial pathways of apoptosis and brain development.

  Hiroki Yoshida;Hiroki Yoshida;Young-Yun Kong;Young-Yun Kong;Ritsuko Yoshida;Ritsuko Yoshida;Andrew J Elia;Andrew J Elia

  1444
  Citations

• Catalytic activity of the caspase-8–FLIP L complex inhibits RIPK3-dependent necrosis

  Andrew Oberst;Christopher P. Dillon;Ricardo Weinlich;Laura L. McCormick

  1320
  Citations

• RIP3 mediates the embryonic lethality of caspase-8-deficient mice

  William J. Kaiser;Jason W. Upton;Alyssa B. Long;Devon Livingston-Rosanoff

  1142
  Citations

• Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

  Minna Woo;Razqallah Hakem;Maria S. Soengas;Gordon S. Duncan

  1116
  Citations

• Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

  M S Soengas;R M Alarcón;H Yoshida;A J Giaccia

  964
  Citations

• The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the Mouse

  Razqallah Hakem;Razqallah Hakem;José Luis de la Pompa;José Luis de la Pompa;Christian Sirard;Christian Sirard;Rong Mo

  839
  Citations

• Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation

  Roger P. Leng;Yunping Lin;Weili Ma;Hong Wu

  830
  Citations

• BNIP3 and Genetic Control of Necrosis-Like Cell Death through the Mitochondrial Permeability Transition Pore

  C. Vande Velde;J. Cizeau;D. Dubik;J. Alimonti

  767
  Citations

• DNA-damage repair; the good, the bad, and the ugly.

  Razqallah Hakem

  633
  Citations

• Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

  Leonardo Salmena;Benedicte Lemmers;Anne Hakem;Elzbieta Matysiak-Zablocki

  599
  Citations

• Requirement for Caspase-8 in NF-κB Activation by Antigen Receptor

  Helen Su;Nicolas Bidère;Lixin Zheng;Alan Cubre

  534
  Citations

• Dysregulation of the mevalonate pathway promotes transformation

  James W. Clendening;Aleks Pandyra;Paul C. Boutros;Samah El Ghamrasni

  436
  Citations

• Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

  Hiroshi Nishina;Klaus D. Fischer;Klaus D. Fischer;Laszlo Radvanyi;Arda Shahinian

  436
  Citations

• Brca2 is required for embryonic cellular proliferation in the mouse.

  A. Suzuki;J. L. De La Pompa;J. L. De La Pompa;R. Hakem;R. Hakem;A. Elia;A. Elia

  344
  Citations

• Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

  R Hakem;J L de la Pompa;J L de la Pompa;A Elia;A Elia;J Potter;J Potter

  320
  Citations

• Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

  John Peter McPherson;Laura Tamblyn;Andrew Elia;Eva Migon

  225
  Citations

• Involvement of mammalian Mus81 in genome integrity and tumor suppression.

  John Peter McPherson;John Peter McPherson;Bénédicte Lemmers;Bénédicte Lemmers;Richard Chahwan;Richard Chahwan;Ashwin Pamidi;Ashwin Pamidi

  223
  Citations

• The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

  Silvia Alvarez-Diaz;Christopher P. Dillon;Najoua Lalaoui;Najoua Lalaoui;Maria C. Tanzer;Maria C. Tanzer

  215
  Citations