World's Best Scientists 2026 revealed!
Andrew E. H. Elia

Andrew E. H. Elia

D-Index & Metrics

Biology and Biochemistry

D-Index
41
Citations
16234
World Ranking
19522
National Ranking
7956

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His primary areas of investigation include Molecular biology, Embryonic stem cell, Cell biology, Cancer research and Apoptosis. His studies in Molecular biology integrate themes in fields like Gastrulation and Endoderm. His Embryonic stem cell research includes themes of Tumor suppressor gene and Embryo, Embryogenesis.

His Cell biology study incorporates themes from Caspase-9, Caspase, APAF1 and Cell culture. The concepts of his Cancer research study are interwoven with issues in Lymphocyte proliferation, In vitro, Tyrosine phosphorylation, CARD11 and MAPK/ERK pathway. His biological study spans a wide range of topics, including Stem cell and Antigen.

His most cited work include:

  • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells (1632 citations)
  • Differential requirement for caspase 9 in apoptotic pathways in vivo (1174 citations)
  • Differential requirement for caspase 9 in apoptotic pathways in vivo (1174 citations)

What are the main themes of his work throughout his whole career to date?

Andrew E. H. Elia focuses on Cell biology, Molecular biology, Cancer research, Apoptosis and Biochemistry. The study incorporates disciplines such as Genetics, Cell, DNA damage, Carcinogenesis and DNA repair in addition to Cell biology. The various areas that Andrew E. H. Elia examines in his Molecular biology study include Embryonic stem cell, Mesoderm, B cell and Antigen.

Andrew E. H. Elia interconnects Cell culture, Centrosome duplication and Cytochrome c in the investigation of issues within Embryonic stem cell. His Cancer research research incorporates elements of Isocitrate dehydrogenase, PTEN and MAPK/ERK pathway. His research combines Stem cell and Apoptosis.

He most often published in these fields:

  • Cell biology (81.03%)
  • Molecular biology (48.28%)
  • Cancer research (22.41%)

What were the highlights of his more recent work (between 2013-2020)?

  • Cell biology (81.03%)
  • DNA repair (22.41%)
  • DNA damage (15.52%)

In recent papers he was focusing on the following fields of study:

Cell biology, DNA repair, DNA damage, Genetics and Control of chromosome duplication are his primary areas of study. His work on Phosphorylation as part of general Cell biology research is frequently linked to Replication protein A, bridging the gap between disciplines. His Phosphorylation study combines topics in areas such as Yeast, Kinase, TOR signaling and Proteomics.

His work on DNA replication, Methyl methanesulfonate, Genome instability and Checkpoint Kinase 2 as part of general Genetics research is frequently linked to Schizosaccharomyces, thereby connecting diverse disciplines of science. His studies deal with areas such as Molecular biology and Origin recognition complex as well as Control of chromosome duplication. As a member of one scientific family, Andrew E. H. Elia mostly works in the field of Ubiquitin, focusing on Quantitative proteomics and, on occasion, Acetylation.

Between 2013 and 2020, his most popular works were:

  • Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression (446 citations)
  • Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. (179 citations)
  • RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks (59 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in DNA repair, Cell biology, Malignant transformation, Ter protein and Molecular biology. His DNA repair research incorporates themes from Quantitative proteomics, DNA damage and Proliferating cell nuclear antigen. His work carried out in the field of Cell biology brings together such families of science as Proteome, Ubiquitin and Acetylation.

His biological study deals with issues like Tumor progression, which deal with fields such as Cancer cell, Antioxidant and Cancer research. His research in Ter protein intersects with topics in Replication factor C and Origin recognition complex. His study on Molecular biology is mostly dedicated to connecting different topics, such as Minichromosome maintenance.

Best Publications

  • Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

    Surya M. Nauli;Francis J. Alenghat;Ying Luo;Eric Williams

  • Differential requirement for caspase 9 in apoptotic pathways in vivo

    Razqallah Hakem;Razqallah Hakem;Anne Hakem;Anne Hakem;Gordon S Duncan;Gordon S Duncan;Jeffrey T Henderson

  • Proteomic Screen Finds pSer/pThr-Binding Domain Localizing Plk1 to Mitotic Substrates

    Andrew E. H. Elia;Lewis C. Cantley;Michael B. Yaffe

  • Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

    Isaac S. Harris;Aislinn E. Treloar;Satoshi Inoue;Masato Sasaki

  • The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.

    Andrew E.H. Elia;Peter Rellos;Lesley F. Haire;Jerry W. Chao

  • Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

    Jürgen Ruland;Jürgen Ruland;Gordon S Duncan;Gordon S Duncan;Andrew Elia;Andrew Elia;Ivan del Barco Barrantes;Ivan del Barco Barrantes

  • The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses

    Woong-Kyung Suh;Beata U Gajewska;Hitoshi Okada;Matthew A Gronski

  • The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

    Christian Sirard;Christian Sirard;José Luis de la Pompa;José Luis de la Pompa;Andrew Elia;Andrew Elia;Annick Itie;Annick Itie

  • Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.

    Stéphanie A. Backman;Vuk Stambolic;Akira Suzuki;Jillian Haight

  • MAPKAP Kinase-2 Is a Cell Cycle Checkpoint Kinase that Regulates the G2/M Transition and S Phase Progression in Response to UV Irradiation

    Isaac A. Manke;Anhco Nguyen;Daniel Lim;Mary Q. Stewart

  • Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

    Kathrin Zaugg;Yi Yao;Patrick T. Reilly;Karuppiah Kannan

  • Phosphoserine/threonine-binding domains.

    Michael B Yaffe;Andrew E.H Elia

  • Global identification of modular cullin-RING ligase substrates.

    Michael J. Emanuele;Andrew E.H. Elia;Qikai Xu;Qikai Xu;Qikai Xu;Claudio R. Thoma;Claudio R. Thoma;Claudio R. Thoma

  • Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis.

    Zhenyue Hao;Zhenyue Hao;Gordon S. Duncan;Gordon S. Duncan;Chia Che Chang;Chia Che Chang;Andrew Elia;Andrew Elia

  • Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

    Andrew E.H. Elia;Alexander P. Boardman;Alexander P. Boardman;David C. Wang;David C. Wang;Edward L. Huttlin

  • The C2 domain of PKCdelta is a phosphotyrosine binding domain.

    Cyril H. Benes;Ning Wu;Andrew E.H. Elia;Tejal Dharia

  • Fas Receptor Expression in Germinal-Center B Cells Is Essential for T and B Lymphocyte Homeostasis

    Zhenyue Hao;Gordon S. Duncan;Jane Seagal;Yu Wen Su

  • Generation and characterization of Smac/DIABLO-deficient mice.

    Hitoshi Okada;Woong Kyung Suh;Woong Kyung Suh;Jianping Jin;Minna Woo;Minna Woo

  • Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

    John Peter McPherson;Laura Tamblyn;Andrew Elia;Eva Migon

  • Erratum: Global identification of modular cullin-ring ligase substrates (Cell (2011) 147 (459-475))

    Michael J. Emanuele;Andrew E.H. Elia;Qikai Xu;Claudio R. Thoma

Frequent Co-Authors

Stephen J. Elledge
Stephen J. Elledge Harvard University
Andrew Wakeham
Andrew Wakeham Princess Margaret Cancer Centre
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Gordon S. Duncan
Gordon S. Duncan University Health Network
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
José Luis de la Pompa
José Luis de la Pompa Spanish National Centre for Cardiovascular Research
Razqallah Hakem
Razqallah Hakem University of Toronto
Shelley L. Berger
Shelley L. Berger University of Pennsylvania

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Andrew E. H. Elia

Trending Scientists