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D-Index & Metrics

Biology and Biochemistry

D-Index
48
Citations
6362
World Ranking
18504
National Ranking
7551

Overview

Tomasz Heyduk is affiliated with Saint Louis University in the United States. Their research contributions focus primarily on biochemistry, genetics, and molecular biology, encompassing six publications in these fields. The subfields addressed in their work include molecular biology, cell biology, physiology, and biophysics.

The scientist's research topics cover multiple areas related to RNA and cellular stress mechanisms. These include:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Cancer-related gene regulation
  • Endoplasmic Reticulum Stress and Disease
  • Adenosine and Purinergic Signaling
  • Advanced Fluorescence Microscopy Techniques

Tomasz Heyduk has published in notable scientific journals such as:

  • Frontiers in Neuroscience
  • ChemBioChem

Two recent papers exemplify their research focus and outputs:

  • "TDP-43 Oligomerization and Phase Separation Properties Are Necessary for Autoregulation", 2022, published in Frontiers in Neuroscience
  • "Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase", 2020, published in ChemBioChem

Collaboration has been an aspect of their research efforts, working alongside frequent coauthors including Lydia C. Koehler, Zachary R. Grese, Alliny C.S. Bastos, Lohany D. Mamede, and Yuna M. Ayala.

Best Publications

  • Transcription Activation at Class II CAP-Dependent Promoters: Two Interactions between CAP and RNA Polymerase

    Wei Niu;Younggyu Kim;Gregory Tau;Tomasz Heyduk

  • Molecular beacons for detecting DNA binding proteins.

    Tomasz Heyduk;Ewa Heyduk

  • Measuring protein conformational changes by FRET/LRET.

    Tomasz Heyduk

  • Application of fluorescence energy transfer and polarization to monitor Escherichia coli cAMP receptor protein and lac promoter interaction

    Tomasz Heyduk;James C. Lee

  • Nucleic acid-based fluorescence sensors for detecting proteins.

    Ewa Heyduk;Tomasz Heyduk

  • Fluorescence anisotropy: Rapid, quantitative assay for protein-DNA and protein-protein interaction

    Tomasz Heyduk;Yuexing Ma;Hong Tang;Richard H. Ebright

  • A Role for Interaction of the RNA Polymerase Flap Domain with the σ Subunit in Promoter Recognition

    Konstantin Kuznedelov;Leonid Minakhin;Anita Niedziela-Majka;Simon L. Dove

  • Escherichia coli cAMP receptor protein: evidence for three protein conformational states with different promoter binding affinities.

    Tomasz Heyduk;James C. Lee

  • Mapping protein domains involved in macromolecular interactions: a novel protein footprinting approach.

    Ewa Heyduk;Tomasz Heyduk

  • Core RNA Polymerase from E. coli Induces a Major Change in the Domain Arrangement of the σ70 Subunit

    Sandhya Callaci;Ewa Heyduk;Tomasz Heyduk

  • Thiol-reactive, luminescent Europium chelates: luminescence probes for resonance energy transfer distance measurements in biomolecules.

    Ewa Heyduk;Tomasz Heyduk

  • CAP interacts with RNA polymerase in solution in the absence of promoter DNA

    Tomasz Heyduk;Tomasz Heyduk;James C. Lee;Yon W. Ebright;Erich E. Blatter

  • A Coiled-Coil from the RNA Polymerase β′ Subunit Allosterically Induces Selective Nontemplate Strand Binding by σ70

    Brian A. Young;Larry C. Anthony;Tanja M. Gruber;Terrance M. Arthur

  • Zinc inhibition of cAMP signaling.

    Claudette Klein;Roger K. Sunahara;Tracie Y. Hudson;Tomasz Heyduk

  • Determinants of RNA polymerase alpha subunit for interaction with beta, beta', and sigma subunits: hydroxyl-radical protein footprinting

    Tomasz Heyduk;Ewa Heyduk;Konstantin Severinov;Hong Tang

  • Phosphorylation Site Mutations in Heterochromatin Protein 1 (HP1) Reduce or Eliminate Silencing Activity

    Tao Zhao;Tomasz Heyduk;Joel C. Eissenberg

  • Molecular pincers: antibody-based homogeneous protein sensors.

    Ewa Heyduk;Benjamin Dummit;Yie-Hwa Chang;Tomasz Heyduk

  • A basal promoter element recognized by free RNA polymerase σ subunit determines promoter recognition by RNA polymerase holoenzyme

    Andrey Feklistov;Nataliya Barinova;Anastasiya Sevostyanova;Ewa Heyduk

  • Conformational Changes of DNA Induced by Binding ofChironomus High Mobility Group Protein 1a (cHMG1a) REGIONS FLANKING AN HMG1 BOX DOMAIN DO NOT INFLUENCE THE BEND ANGLE OF THE DNA

    Ewa Heyduk;Tomasz Heyduk;Peter Claus;Jacek R. Wiśniewski

  • Mapping Protein Domains Involved in Macromolecular Interactions: A Novel Protein Footprinting Approach. [Erratum to document cited in CA121:103552]

    Ewa Heyduk;Tomasz Heyduk

Frequent Co-Authors

Konstantin Severinov
Konstantin Severinov Rutgers, The State University of New Jersey
Richard H. Ebright
Richard H. Ebright Rutgers, The State University of New Jersey
Jacek R. Wiśniewski
Jacek R. Wiśniewski Max Planck Society
James Lee
James Lee The Francis Crick Institute
Richard R. Burgess
Richard R. Burgess University of Wisconsin–Madison
Hong Tang
Hong Tang Chinese Academy of Sciences
Jörn Bullerdiek
Jörn Bullerdiek University of Bremen
Ann Hochschild
Ann Hochschild Harvard University
Seth A. Darst
Seth A. Darst Rockefeller University
Roger K. Sunahara
Roger K. Sunahara University of California, San Diego

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