Ann Hochschild

Research.com Recognitions

• 2020 - Fellow of the American Academy of Arts and Sciences

Overview

Best Publications

• Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

  David Bikard;Wenyan Jiang;Poulami Samai;Ann Hochschild

  1545
  Citations

• Cooperative binding of λ repressors to sites separated by integral turns of the DNA helix

  A. Hochschild;M. Ptashne

  572
  Citations

• Repressor structure and the mechanism of positive control

  Ann Hochschild;Nina Irwin;Mark Ptashne

  419
  Citations

• Activation of prokaryotic transcription through arbitrary protein–protein contacts

  S L Dove;J K Joung;A Hochschild

  411
  Citations

• Interaction trap assay, reagents and uses thereof

  Simon Dove;J. Keith Joung;Ann Hochschild

  390
  Citations

• CarD Is an Essential Regulator of rRNA Transcription Required for Mycobacterium tuberculosis Persistence

  Christina L. Stallings;Nicolas C. Stephanou;Linda Chu;Ann Hochschild

  257
  Citations

• Conversion of the omega subunit of Escherichia coli RNA polymerase into a transcriptional activator or an activation target.

  Simon L. Dove;Ann Hochschild

  238
  Citations

• Structural Basis for Bacterial Transcription-Coupled DNA Repair

  Alexandra M. Deaconescu;Anna L. Chambers;Anna L. Chambers;Abigail J. Smith;Bryce E. Nickels

  234
  Citations

• Cooperativity in long-range gene regulation by the λ CI repressor

  Ian B. Dodd;Keith E. Shearwin;Alison J. Perkins;Tom Burr

  216
  Citations

• Crystal Structure of the λ Repressor C-Terminal Domain Provides a Model for Cooperative Operator Binding

  Charles E. Bell;Paolo Frescura;Ann Hochschild;Mitchell Lewis

  207
  Citations

• A Role for Interaction of the RNA Polymerase Flap Domain with the σ Subunit in Promoter Recognition

  Konstantin Kuznedelov;Leonid Minakhin;Anita Niedziela-Majka;Simon L. Dove

  205
  Citations

• DNA loops induced by cooperative binding of λ repressor

  Jack Griffith;Ann Hochschild;Mark Ptashne

  201
  Citations

• Protein–Protein Contacts that Activate and Repress Prokaryotic Transcription

  Ann Hochschild;Simon L Dove

  196
  Citations

• Escherichia coli one- and two-hybrid systems for the analysis and identification of protein-protein interactions.

  James C. Hu;Michael G. Kornacker;Ann Hochschild

  184
  Citations

• A bacterial two-hybrid system based on transcription activation.

  Simon L. Dove;Ann Hochschild

  170
  Citations

• A bacterial global regulator forms a prion

  Andy H. Yuan;Ann Hochschild

  169
  Citations

• Region 4 of σ as a target for transcription regulation

  Simon L. Dove;Seth A. Darst;Ann Hochschild

  154
  Citations

• Mutant lambda phage repressor with a specific defect in its positive control function

  Leonard Guarente;Jeffrey S. Nye;Ann Hochschild;Mark Ptashne

  137
  Citations

• Amino acid substitutions in the -35 recognition motif of sigma 70 that result in defects in phage lambda repressor-stimulated transcription.

  N Kuldell;A Hochschild

  131
  Citations

• Crystal structure of the λ repressor and a model for pairwise cooperative operator binding

  Steven Stayrook;Peera Jaru-Ampornpan;Peera Jaru-Ampornpan;Jenny Ni;Ann Hochschild

  126
  Citations