World's Best Scientists 2026 revealed!
Akira Ishihama

Akira Ishihama

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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Microbiology

D-Index
103
Citations
36005
World Ranking
352
National Ranking
8

Molecular Biology

D-Index
103
Citations
35857
World Ranking
479
National Ranking
33

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Akira Ishihama was affiliated with Hosei University in Japan. Their research contributions spanned the field of Biochemistry, Genetics and Molecular Biology, with a total of 39 publications. Within this main field, their work focused extensively on Molecular Biology, Genetics, Ecology, Neurology, and Environmental Chemistry.

The research topics covered by Ishihama included:

  • Bacterial Genetics and Biotechnology
  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Neurogenetic and Muscular Disorders Research
  • Bacteriophages and microbial interactions
  • Amyotrophic Lateral Sclerosis Research
  • CRISPR and Genetic Engineering

Frequent co-authors who collaborated with Ishihama were:

  • Tomohiro Shimada
  • Akira Ishiguro
  • Takumi Anzai
  • Hiroshi Ogasawara
  • Ikki Kobayashi

Common venues for Ishihama's publications included:

  • International Journal of Molecular Sciences (4 publications)
  • Microbial Genomics (3 publications)
  • FEBS Letters (2 publications)
  • Microbiology (2 publications)
  • Scientific Reports (2 publications)

Among recent publications, Ishihama contributed to several research articles notable for their focus on molecular mechanisms, transcriptional regulation, and neurological disease:

  • "Hierarchy of transcription factor network in Escherichia coli K-12: H-NS-mediated silencing and Anti-silencing by global regulators," 2021, published in FEMS Microbiology Reviews
  • "ALS-linked FUS mutations dysregulate G-quadruplex-dependent liquid-liquid phase separation and liquid-to-solid transition," 2021, Journal of Biological Chemistry (authored by Akira Ishiguro)
  • "Molecular dissection of ALS-linked TDP-43 - involvement of the Gly-rich domain in interaction with G-quadruplex mRNA," 2020, FEBS Letters (authored by Akira Ishiguro)
  • "Expanded roles of pyruvate-sensing PdhR in transcription regulation of the Escherichia coli K-12 genome: fatty acid catabolism and cell motility," 2020, Microbial Genomics (authored by Takumi Anzai)
  • "Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis," 2021, ACS Central Science (authored by Mahima Sharma)

Best Publications

  • Growth Phase-Dependent Variation in Protein Composition of the Escherichia coli Nucleoid

    Talukder Ali Azam;Akira Iwata;Akiko Nishimura;Susumu Ueda

  • A third recognition element in bacterial promoters: DNA binding by the alpha subunit of RNA polymerase

    Wilma Ross;Khoosheh K. Gosink;Julia Salomon;Kazuhiko Igarashi

  • Functional modulation of Escherichia coli RNA polymerase

    Akira Ishihama

  • Twelve Species of the Nucleoid-associated Protein from Escherichia coli SEQUENCE RECOGNITION SPECIFICITY AND DNA BINDING AFFINITY

    Talukder Ali Azam;Akira Ishihama

  • Functional characterization in vitro of all two-component signal transduction systems from Escherichia coli.

    Kaneyoshi Yamamoto;Kiyo Hirao;Taku Oshima;Hirofumi Aiba

  • Regulation of RNA polymerase sigma subunit synthesis in Escherichia coli: intracellular levels of four species of sigma subunit under various growth conditions.

    M Jishage;A Iwata;S Ueda;A Ishihama

  • Bipartite functional map of the E. coli RNA polymerase α subunit: Involvement of the C-terminal region in transcription activation by cAMP-CRP

    Kazuhiko Igarashi;Akira Ishihama

  • Competition among seven Escherichia coli σ subunits: relative binding affinities to the core RNA polymerase

    Hiroto Maeda;Nobuyuki Fujita;Akira Ishihama

  • Heterogeneity of the principal sigma factor in Escherichia coli: the rpoS gene product, sigma 38, is a second principal sigma factor of RNA polymerase in stationary-phase Escherichia coli.

    Kan Tanaka;Yuko Takayanagi;Nobuyuki Fujita;Akira Ishihama

  • Protein-protein communication within the transcription apparatus

    Unknown

  • Single-Molecule Imaging of RNA Polymerase-DNA Interactions in Real Time

    Yoshie Harada;Takashi Funatsu;Katsuhiko Murakami;Yoshikazu Nonoyama

  • Transcriptional response of Escherichia coli to external copper

    Kaneyoshi Yamamoto;Akira Ishihama;Akira Ishihama

  • Prokaryotic genome regulation: multifactor promoters, multitarget regulators and hierarchic networks.

    Akira Ishihama

  • Novel roles of cAMP receptor protein (CRP) in regulation of transport and metabolism of carbon sources.

    Tomohiro Shimada;Nobuyuki Fujita;Kaneyoshi Yamamoto;Akira Ishihama

  • Two types of localization of the DNA-binding proteins within the Escherichia coli nucleoid.

    Talukder Ali Azam;Sota Hiraga;Akira Ishihama

  • Structure and probable genetic location of a "ribosome modulation factor" associated with 100S ribosomes in stationary-phase Escherichia coli cells.

    Akira Wada;Yukiko Yamazaki;Nobuyuki Fujita;Akira Ishihama

  • Molecular assembly of influenza virus : association of the NS2 protein with virion matrix

    Jiro Yasuda;Susumu Nakada;Atsushi Kato;Tetsuya Toyoda

  • Promoter selectivity of Escherichia coli RNA polymerase E sigma 70 and E sigma 38 holoenzymes. Effect of DNA supercoiling.

    Shuichi Kusano;Quinquan Ding;Nobuyuki Fujita;Akira Ishihama

  • A stationary phase protein in Escherichia coli with binding activity to the major σ subunit of RNA polymerase

    Miki Jishage;Akira Ishihama

  • Unprecedented High-Resolution View of Bacterial Operon Architecture Revealed by RNA Sequencing

    Tyrrell Conway;James P. Creecy;Scott M. Maddox;Joe E. Grissom

  • Regulation of the phosphate regulon of Escherichia coli: Activation of pstS transcription by PhoB protein in vitro

    Kozo Makino;Hideo Shinagawa;Mitsuko Amemura;Sigenobu Kimura

  • GENETICS OF BACTERIAL RNA POLYMERASES

    Takashi Yura;Akira Ishihama

Frequent Co-Authors

Nobuyuki Fujita
Nobuyuki Fujita National Institute of Genetics
Kazuei Igarashi
Kazuei Igarashi Chiba University
Katsuhiko S. Murakami
Katsuhiko S. Murakami Pennsylvania State University
Keiko Kashiwagi
Keiko Kashiwagi Chiba Institute of Science
Kazuhiko Igarashi
Kazuhiko Igarashi Tohoku University
Atsushi Kato
Atsushi Kato Northwestern University
Stephen J. W. Busby
Stephen J. W. Busby University of Birmingham
Kan Tanaka
Kan Tanaka Tokyo Institute of Technology
Annie Kolb
Annie Kolb Institut Pasteur
Makoto Kobayashi
Makoto Kobayashi University of Tsukuba

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