What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Cell biology, Cancer research, Immunology, Apoptosis and Molecular biology.
Tak W. Mak is interested in Signal transduction, which is a field of Cell biology.
His studies deal with areas such as Cancer, IDH2, IDH1, Regulator and PTEN as well as Cancer research.
Tak W. Mak combines subjects such as Protein kinase B and Hamartoma with his study of PTEN.
He frequently studies issues relating to Cytotoxic T cell and Immunology.
Tak W. Mak interconnects DNA damage and Antigen in the investigation of issues within Molecular biology.
His most cited work include:
- Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4 (2331 citations)
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN (2101 citations)
- Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN (2101 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Cell biology, Cancer research, Immunology, Molecular biology and T cell.
His Cell biology study integrates concerns from other disciplines, such as Apoptosis, Receptor, Embryonic stem cell and T-cell receptor.
His Cancer research study combines topics in areas such as Carcinogenesis, Cancer, Kinase, Programmed cell death and PTEN.
His biological study spans a wide range of topics, including Tumor suppressor gene and Protein kinase B.
His Immunology research is multidisciplinary, incorporating elements of Lipocalin and In vivo.
His T cell research integrates issues from B cell and Antigen.
He most often published in these fields:
- Cell biology (55.14%)
- Cancer research (37.38%)
- Immunology (32.40%)
What were the highlights of his more recent work (between 2013-2021)?
- Cancer research (37.38%)
- Cancer (8.72%)
- Cell biology (55.14%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cancer research, Cancer, Cell biology, Immunology and PI3K/AKT/mTOR pathway.
The Cancer research study combines topics in areas such as Protein kinase B, Cancer cell, Lung cancer, Kinase and PTEN.
His work on Tensin is typically connected to TRPC6 as part of general PTEN study, connecting several disciplines of science.
Tak W. Mak is interested in Wnt signaling pathway, which is a branch of Cell biology.
The various areas that he examines in his Immunology study include Receptor, Cellular differentiation and Lipocalin.
His PI3K/AKT/mTOR pathway research incorporates themes from GCLC and Glutathione.
Between 2013 and 2021, his most popular works were:
- Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression (446 citations)
- CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. (177 citations)
- Glutathione Primes T Cell Metabolism for Inflammation (154 citations)
In his most recent research, the most cited papers focused on:
Tak W. Mak spends much of his time researching Cancer research, Cancer, Mutation, Breast cancer and PI3K/AKT/mTOR pathway.
His research in Cancer research intersects with topics in Cancer cell, Abemaciclib, Lymph node, Tumor progression and PTEN.
His Cancer research includes themes of Chromatin remodeling, Biobank and Antibody, Immunology.
In his study, which falls under the umbrella issue of Immunology, Cell biology is strongly linked to Aryl hydrocarbon receptor.
In general Cell biology, his work in Wnt signaling pathway is often linked to Intestinal epithelium linking many areas of study.
His Mutation research includes elements of Histone methylation, DNA methylation, Mutant, Molecular biology and Leukemia.
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