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Biology and Biochemistry

D-Index
57
Citations
25989
World Ranking
13515
National Ranking
467

Overview

Andrew J. Elia is affiliated with the Princess Margaret Cancer Centre in Canada, contributing to research primarily in the fields of Biochemistry, Genetics, and Molecular Biology, with a focus also on Medicine. Their scholarly work encompasses a range of subfields, including Molecular Biology, Genetics, Cancer Research, Immunology, and Pathology and Forensic Medicine.

Their research covers several topics with notable frequency, including:

  • Epigenetics and DNA Methylation
  • Glioma Diagnosis and Treatment
  • DNA Repair Mechanisms
  • Genomics and Chromatin Dynamics
  • Vagus Nerve Stimulation Research
  • Microtubule and mitosis dynamics
  • Renal and related cancers

Elia has published extensively in multiple venues, with frequent contributions to:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology
  • Science
  • Cancer Cell

Among recent publications are:

  • A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation, 2022, Science
  • Therapeutic inhibition of USP9x-mediated Notch signaling in triple-negative breast cancer, 2021, Proceedings of the National Academy of Sciences
  • IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment, 2023, Cancer Cell
  • Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma, 2023, Nature Cancer
  • Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer, 2022, Cancer Discovery

Frequent co-authors collaborating with Andrew J. Elia include:

  • Tak W. Mak
  • Ricky Tsai
  • Khalid N. Al-Zahrani
  • Jérôme Fortin
  • Daniel Schramek

Best Publications

  • Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

    Nicholas Joza;Nicholas Joza;Santos A. Susin;Eric Daugas;William L. Stanford

  • Differential requirement for caspase 9 in apoptotic pathways in vivo

    Razqallah Hakem;Razqallah Hakem;Anne Hakem;Anne Hakem;Gordon S Duncan;Gordon S Duncan;Jeffrey T Henderson

  • Apaf1 is required for mitochondrial pathways of apoptosis and brain development.

    Hiroki Yoshida;Hiroki Yoshida;Young-Yun Kong;Young-Yun Kong;Ritsuko Yoshida;Ritsuko Yoshida;Andrew J Elia;Andrew J Elia

  • Retinal Stem Cells in the Adult Mammalian Eye

    Vincent Tropepe;Brenda L. K. Coles;Bernard J. Chiasson;D. Jonathan Horsford

  • FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis

    Wen-Chen Yeh;José Luis de la Pompa;Mila E. McCurrach;Hong-Bing Shu

  • Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

    Tony L. Parkes;Andrew J. Elia;Dale Dickinson;Arthur J. Hilliker

  • High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

    Akira Suzuki;José Luis de la Pompa;Vuk Stambolic;Andrew J. Elia

  • Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

    Isaac S. Harris;Aislinn E. Treloar;Satoshi Inoue;Masato Sasaki

  • Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.

    Seiji Hitoshi;Tania Alexson;Vincent Tropepe;Dorit Donoviel

  • Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice

    Dorothea Rudolph;Wen-Chen Yeh;Andrew Wakeham;Bettina Rudolph

  • Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

    José Luis de la Pompa;Luika A. Timmerman;Hiroaki Takimoto;Hiroki Yoshida

  • Bcl10 Is a Positive Regulator of Antigen Receptor–Induced Activation of NF-κ B and Neural Tube Closure

    Jürgen Ruland;Jürgen Ruland;Gordon S Duncan;Gordon S Duncan;Andrew Elia;Andrew Elia;Ivan del Barco Barrantes;Ivan del Barco Barrantes

  • The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses

    Woong-Kyung Suh;Beata U Gajewska;Hitoshi Okada;Matthew A Gronski

  • Requirement for Casper (c-FLIP) in Regulation of Death Receptor–Induced Apoptosis and Embryonic Development

    Wen-Chen Yeh;Annick Itie;Andrew J Elia;Michelle Ng

  • Genetic evidence for functional redundancy of Platelet/Endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions.

    G S Duncan;D P Andrew;H Takimoto;H Takimoto;S A Kaufman

  • Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.

    Stéphanie A. Backman;Vuk Stambolic;Akira Suzuki;Jillian Haight

  • Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury

    Thorsten Berger;Atsushi Togawa;Gordon S. Duncan;Andrew J. Elia

  • Deficiency of T2K leads to apoptotic liver degeneration and impaired NF‐κB‐dependent gene transcription

    Madeleine Bonnard;Christine Mirtsos;Shinobu Suzuki;Kevin Graham

  • Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress

    Kathrin Zaugg;Yi Yao;Patrick T. Reilly;Karuppiah Kannan

  • Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.

    Atsushi Hirao;Alison Cheung;Gordon Duncan;Pierre Marie Girard

Frequent Co-Authors

Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Andrew Wakeham
Andrew Wakeham Princess Margaret Cancer Centre
Tak W. Mak
Tak W. Mak Princess Margaret Cancer Centre
Pamela S. Ohashi
Pamela S. Ohashi Princess Margaret Cancer Centre
Gerry Melino
Gerry Melino University of Rome Tor Vergata
Razqallah Hakem
Razqallah Hakem University of Toronto
Gordon S. Duncan
Gordon S. Duncan University Health Network
José Luis de la Pompa
José Luis de la Pompa Spanish National Centre for Cardiovascular Research
Kazuo Yamamoto
Kazuo Yamamoto University of Tokyo
Scott W. Lowe
Scott W. Lowe Memorial Sloan Kettering Cancer Center

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