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Derek van der Kooy

Derek van der Kooy

D-Index & Metrics

Neuroscience

D-Index
93
Citations
34535
World Ranking
981
National Ranking
53

Overview

Derek van der Kooy is affiliated with the University of Toronto in Canada. Their research spans several interdisciplinary fields with a focus on molecular biology and neuroscience. The main areas of study include biochemistry, genetics, and molecular biology with 26 publications, neuroscience with 22 publications, and medicine with 18 publications. Within these broader domains, subfields such as molecular biology, cellular and molecular neuroscience, radiology, nuclear medicine and imaging, clinical psychology, and aging are prominently represented.

The scientist's work addresses multiple key topics, particularly in retinal research and neurobiology. These topics include:

  • Retinal Development and Disorders
  • Neurotransmitter Receptor Influence on Behavior
  • Retinal and Macular Surgery
  • Nicotinic Acetylcholine Receptors Study
  • Single-cell and spatial transcriptomics
  • Corneal Surgery and Treatments
  • Genetics, Aging, and Longevity in Model Organisms

Frequent publication venues for Derek van der Kooy include:

  • European Journal of Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biomaterials
  • Stem Cell Research & Therapy
  • International Journal of Molecular Sciences

Their regular collaborators frequently include Brenda L.K. Coles, Taryn E. Grieder, Mandy Yee, Geith Maal-Bared, and Michael Bergamini.

Among recent scientific papers, notable publications include:

  • "The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury," 2020, Stem Cells Translational Medicine
  • "Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute," 2021, Biomaterials
  • "Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration," 2020, Biomaterials
  • "Glucocorticoid agonists enhance retinal stem cell self-renewal and proliferation," 2021, Stem Cell Research & Therapy
  • "Administration of BDNF in the ventral tegmental area produces a switch from a nicotine-non-dependent D1R-mediated motivational state to a nicotine-dependent-like D2R-mediated motivational state," 2021, European Journal of Neuroscience

Best Publications

  • Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells

    Cindi M. Morshead;Brent A. Reynolds;Constance G. Craig;Michael W. McBurney

  • Retinal Stem Cells in the Adult Mammalian Eye

    Vincent Tropepe;Brenda L. K. Coles;Bernard J. Chiasson;D. Jonathan Horsford

  • Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.

    Vincent Tropepe;Maria Sibilia;Brian G. Ciruna;Brian G. Ciruna;Janet Rossant;Janet Rossant

  • Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism.

    Vincent Tropepe;Seiji Hitoshi;Christian Sirard;Tak W Mak

  • The organization of projections from the cortex, amygdala, and hypothalamus to the nucleus of the solitary tract in rat.

    D van der Kooy;L Y Koda;J F McGinty;C R Gerfen

  • Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells.

    Seiji Hitoshi;Tania Alexson;Vincent Tropepe;Dorit Donoviel

  • Is there a neural stem cell in the mammalian forebrain

    Samuel Weiss;Brent A. Reynolds;Angelo L. Vescovi;Cindi Morshead

  • Adult Mammalian Forebrain Ependymal and Subependymal Cells Demonstrate Proliferative Potential, but only Subependymal Cells Have Neural Stem Cell Characteristics

    Bernard J. Chiasson;Vincent Tropepe;Cindi M. Morshead;Derek van der Kooy

  • Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages

    Raewyn M Seaberg;Simon R Smukler;Timothy J Kieffer;Grigori Enikolopov

  • Adult Rodent Neurogenic Regions: The Ventricular Subependyma Contains Neural Stem Cells, But the Dentate Gyrus Contains Restricted Progenitors

    Raewyn M. Seaberg;Derek van der Kooy

  • Drug reinforcement studied by the use of place conditioning in rat.

    Ronald F. Mucha;Derek Van Der Kooy;Martha O'Shaughnessy;Peter Bucenieks

  • The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour

    Steven R. Laviolette;Derek van der Kooy

  • Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma.

    Vincent Tropepe;Constance G. Craig;Cindi M. Morshead;Derek van der Kooy

  • Developmental expression of a novel murine homeobox gene (Chx10): Evidence for roles in determination of the neuroretina and inner nuclear layer

    Ivy S.C. Liu;Jia-de Chen;Lynda Ploder;Danka Vidgen

  • p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity

    Tod E. Kippin;David J. Martens;Derek van der Kooy

  • Postmitotic death is the fate of constitutively proliferating cells in the subependymal layer of the adult mouse brain

    CM Morshead;D van der Kooy

  • Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations

    Cindi M. Morshead;Patricia Benveniste;Norman N. Iscove;Derek van der Kooy

  • Facile isolation and the characterization of human retinal stem cells

    Brenda L. K. Coles;Brigitte Angénieux;Tomoyuki Inoue;Katia Del Rio-Tsonis

  • Stem and progenitor cells: the premature desertion of rigorous definitions

    Raewyn M Seaberg;Derek van der Kooy

  • Why stem cells

    Derek van der Kooy;and Samuel Weiss

  • Neuronal birthdate underlies the development of striatal compartments.

    Derek van der Kooy;Gordon Fishell

Frequent Co-Authors

Steven R. Laviolette
Steven R. Laviolette University of Western Ontario
Janet Rossant
Janet Rossant University of Toronto
Gord Fishell
Gord Fishell Harvard Medical School
Karim Nader
Karim Nader McGill University
Roderick R. McInnes
Roderick R. McInnes University of Toronto
Samuel Weiss
Samuel Weiss University of Calgary
Olivier George
Olivier George University of California, San Diego
Scott C. Steffensen
Scott C. Steffensen Brigham Young University
Gary D. Bader
Gary D. Bader University of Toronto
Bryan Kolb
Bryan Kolb University of Lethbridge

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